Two-Component Signaling Systems, Part A, Volume 422

1st Edition

Serial Volume Editors: Melvin Simon Brian Crane Alexandrine Crane
Hardcover ISBN: 9780123738516
eBook ISBN: 9780080548715
Imprint: Academic Press
Published Date: 3rd July 2007
Page Count: 592
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Table of Contents

Section I. Computational Analyses of Sequences and Sequence Alignments

CHAPTER 1: Comparative genomic and protein sequence analyses of a complex system controlling bacterial chemotaxis. CHAPTER 2: Two component systems in microbial communities: Approaches and resources for analyzing metagenomic data sets. CHAPTER 3: Identification of sensory and signal-transducing domains in two-component signaling systems. CHAPTER 4: Features of protein-protein interactions in two-component signaling deduced from genomic libraries. CHAPTER 5: Sporulation phosphorelay proteins and their complexes: Crystallographic characterization. CHAPTER 6: Control Analysis of Bacterial Chemotaxis Signaling. CHAPTER 7: Classification of Response Regulators based on their Surface Properties

Section II. Biochemical and Genetic Assays of Individual Components of the Signaling Systems

CHAPTER 8: Purification and Assays of Rhodobacter capsulatus RegB-RegA Two Component Signal Transduction System. CHAPTER 9: Purification and reconstitution of PYP-phytochrome (Ppr) with biliverdin and 4-hydroxycinnamic acid. CHAPTER 10: Oxygen and Redox-Sensing by Two-Component Systems That Regulate Behavioral Responses. Behavioral Assays and Structural Studies of Aer using in vivo Disulfide Crosslinking. CHAPTER 11: Two-Component Signaling in the Virulence of S. aureus: A Silkworm Larvae-Pathogenic Agent Infection Model of Virulence. CHAPTER 12: TonB System, In vivo Assays and Characterization CHAPTER 13: Biochemical Characterization of Plant Ethylene Receptors following Transgenic Expression in Yeast. CHAPTER 14: Structure of SixA, a histidine protein phosphatase of the ArcB HPt domain in E. coli. CHAPTER 15: Triggering and monitoring light-sensing reactions in protein cr


Multicellular organisms must be able to adapt to cellular events to accommodate prevailing conditions. Sensory-response circuits operate by making use of a phosphorylation control mechanism known as the "two-component system."

Sections include: Computational Analyses of Sequences and Sequence Alignments Biochemical and Genetic Assays of Individual Components of Signaling Systems Physiological Assays and Readouts

Key Features

  • Presents detailed protocols
  • Includes troubleshooting tips


Biochemists and researchers in related life science fields.


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© Academic Press 2007
Academic Press
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About the Serial Volume Editors

Melvin Simon Serial Volume Editor

Affiliations and Expertise

The Salk Institute, La Jolla, CA, USA

Brian Crane Serial Volume Editor

Affiliations and Expertise

Cornell University, Ithaca, NY, USA

Alexandrine Crane Serial Volume Editor

Affiliations and Expertise

Cornell University, Ithaca, NY, USA