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Tunneling in Biological Systems - 1st Edition - ISBN: 9780121678609, 9781483271347

Tunneling in Biological Systems

1st Edition

A Colloquium of the Johnson Research Foundation

Editors: Britton Chance Don Charles Devault Hans Frauenfelder
eBook ISBN: 9781483271347
Paperback ISBN: 9781483237152
Hardcover ISBN: 9780121678609
Imprint: Academic Press
Published Date: 28th January 1979
Page Count: 776
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Tunneling in Biological Systems focuses on the low temperature electron transport that reveals a quantum-mechanical effect called “tunneling.” This book discusses the tunneling in physical systems; detection of molecular vibrations with electron tunneling; chemical-rate theory of small-polaron hopping; and experimental approaches to electronic coupling in metal ion redox systems. The Faraday rotation and photoconductivity of photosynthetic structures at microwave frequencies; dynamics of electron transport in macromolecules; and electron transfer reactions in cytochrome oxidase are also elaborated. This text likewise covers the kinetic evidence for electron tunneling in solution; specificity and control in biological systems; molecular tunneling in heme proteins; and ligand binding. This publication is valuable to students and researchers interested in the physics of biological and medical problems.

Table of Contents

List of Contributors


Tunneling in Physical Systems

My Tunneling Experiences

Introductory Comments

Tunneling in Physical Systems


Concepts in Quantum Mechanical Tunneling in Systems of Biological and Chemical Interest


Detection of Molecular Vibrations with Electron Tunneling

Tunneling in Network Models of Molecular Chains

Localized and Delocalized Tunneling States

General Discussion: Formulations of Theory

Tunneling in Chemical Systems

Electron and Nuclear Tunneling in Chemical and Biological Systems


Chemical-Rate Theory of Small-Polaron Hopping


A General Theoretical Approach to Tunneling Transfer and Dissociation

A Quantum Theory of Low-Temperature Chemical and Biological Rate Processes in Condensed Media

Experimental Approaches to Electronic Coupling in Metal Ion Redox Systems


Electron Transfer Reactions of Metal Complexes in Solution


Electron Transfer Properties of the Imidazolate Anion

Electron Transfer in (NH3)5Ru(III)-4-Alkylpyridine- Cu(I) Binuclear Ions

Electron Tunneling after Radiolysis


Tunneling Distances and Exothermic Rate Restrictions in Electron Transfer Reactions

General Discussion: Electron vs. Nuclear Tunneling

General Discussion: Adiabaticity

Tunneling in Biological Systems

Introduction to Biological Aspects

Tunneling in Photosynthetic Systems

Cytochrome-Reaction Center-Quinone Interactions: Models for Biological Electron Transfer


Electron Transfer between c-Type Cytochromes and High Potential Iron-Sulfur Proteins

An Application of Electron Transfer Theory to a Problem in Chloroplast Membrane Topography

Electron Tunneling in Photosystem-I Charge Recombination at Low Temperatures

Some Data of Possible Relevance to Tunneling and Photosynthetic Reaction Centers


The Effects of High Hydrostatic Pressure on Light-Induced Electron Transfer and Proton Binding in Chromatium


Faraday Rotation and Photoconductivity of Photosynthetic Structures at Microwave Frequencies

Nonadiabatic Electron Tunneling: Implications for Bacterial Photosynthesis and for Critical Physical Tests of the Mechanism


Dynamics of Electron Transport in Macromolecules

General Discussion: Temperature Dependence

Tunneling in the Respiratory Chain

Mitochondrial Electron Transfer at Phosphorylation Sites 2 and 3


Electron Transport in the Succinate-Ubiquinone Segment of the Respiratory Chain

Electron Transfer Reactions in Cytochrome Oxidase


Definition of the Surface of Cytochrome c Interacting with Cytochrome Oxidase

Structure/Function Relationships in Biological Electron Transport Proteins


General Discussion: Cytochrome c and Some Other Biological Redox Molecules

Tunneling in Model Biological Systems

Conformational Distribution and Vibronic Coupling in the Blue Copper-Containing Protein Azurin

Overall Charge Control of the Ionic Strength Effects upon the Redox Kinetics of Small Molecule-Protein and Protein-Protein Reactions

the Energy Transforming Function Associated with Electron Transfer Reactions in Biological Systems

Kinetic Evidence for Electron Tunneling in Solution

Fermi-Level Matching: A Possible Condition in Redox Enzyme Specificity

General Discussion: Distances

Specificity and Control in Biological Systems

General Discussion: Biological Specificity and Control

Molecular Tunneling

Molecular Tunneling in Heme Proteins


Heme Ligand Configuration in Photodissociable Ferrous Myoglobin Complexes


General Discussion: Ligand Binding

Quantum Chemical Reactivity Near Absolute Zero: Biological, Chemical, and Astrophysical Aspects


Experimental Approaches

New Methods for Exploring Tunneling Phenomena


General Discussion: Experimental Techniques

Magnetic Interactions and Electron Transfer Kinetics of the Reduced Intermediate Acceptor in Reaction Centers (RCs) of Rhodopseudomonas Sphaeroides R-26. Evidence for Thermally Induced Tunneling

Subject Index


No. of pages:
© Academic Press 1979
28th January 1979
Academic Press
eBook ISBN:
Paperback ISBN:
Hardcover ISBN:

About the Editors

Britton Chance

Britton Chance

Don Charles Devault

Don Charles Devault

Hans Frauenfelder

Hans Frauenfelder

Ratings and Reviews