Transport Proteins

Transport Proteins

1st Edition - January 21, 2021

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  • Editor: Rossen Donev
  • eBook ISBN: 9780128220887
  • Hardcover ISBN: 9780128220870

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Transport Proteins, Volume 123, provides the latest information on the two major groups of transport proteins, those that carry molecules to different locations within a cell or organism and those that carry molecules across otherwise impermeable membranes. Chapters in the updated release include Biology of Iron Transport: Ferroportin, Transport of transition metals across biological membranes, The effect of sport and physical activity on transport proteins: implications for cancer prevention and control, Structural rearrangement in polyketide synthase for improvement its bio-physicochemical properties, Autophagy Proteins and its Homeostasis in Cellular Environment, and much more.

Key Features

  • Integrates experimental and computational methods for studying the structure and function of transport proteins and their implication in drug design
  • Contains timely chapters written by well-renowned authorities in their field
  • Includes a high number of top quality illustrations, figures and tables, and targets a very wide audience of specialists, researchers and students


Protein chemists, molecular cell biologists, immunologists, structural biologists, computational biochemists, medical doctors, pharmacologists and other researchers working in the field of transport proteins and drug design. Articles published here would also be of a considerable benefit to medical, biology and pharmacology students specializing in this field

Table of Contents

  • 1. Biology of the iron efflux transporter, ferroportin
    Gautam Rishi and V. Nathan Subramaniam
    2. The effect of sport and physical activity on transport proteins: implications for cancer prevention and control
    Maha Sellami and Nicola Luigi Bragazzi
    3. Cancer bioenergetics as emerging holistic cancer theory: the role of metabolic fluxes and transport proteins involved in metabolic pathways in the pathogenesis of malignancies. State-of-the-art and future prospects
    Nicola Luigi Bragazzi and Maha Sellami
    4. Investigating mutations at the hotspot position of the ERBB2 and screening for the novel lead compound to treat breast cancer – a computational approach
    D. Thirumal Kumar, S. Udhaya Kumar, R. Magesh and C. George Priya Doss
    5. Autophagy proteins and its homeostasis in cellular environment
    Vrushali Guhe, Bhavnita Soni, Prajakta Ingale and Shailza Singh
    6. Expression of placental glucose transporter proteins in pregnancies complicated by fetal growth disorders
    Pawel Jan Stanirowski, Michal Lipa, Dorota Bomba-Opo and Miroslaw Wielgos
    7. The role of transferrins and iron-related proteins in brain iron transport: applications to neurological diseases
    Camila Campos-Escamilla
    8. ABCG: a new fold of ABC exporters and a whole new bag of riddles!
    Atanu Banerjee, Alexis Moreno, Jorgaq Pata, Pierre Falson and Rajendra Prasad
    9. Serum albumin: clinical significance of drug binding and development as drug delivery vehicle
    Saad Tayyab and Shevin Rizal Feroz
    10. PTR2/POT/NPF transporters: what makes them tick?
    Bala K. Prabhala, Moazur Rahman, Hussam H. Nour-eldin and Flemming Steen Jørgensen and Osman Mirza
    11. Network analysis of transcriptomics data for the prediction and prioritization of membrane-associated biomarkers for idiopathic pulmonary fibrosis (IPF) by bioinformatics approach
    Smriti Mishra, Mohammad Imran Shah, S. Udhaya Kumar, D. Thirumal Kumar, Chandrasekhar Gopalakrishnan, Abeer Mohammed Al-Subaie, R. Magesh, C. George Priya Doss and Balu Kamaraj

Product details

  • No. of pages: 286
  • Language: English
  • Copyright: © Academic Press 2021
  • Published: January 21, 2021
  • Imprint: Academic Press
  • eBook ISBN: 9780128220887
  • Hardcover ISBN: 9780128220870

About the Serial Editor

Rossen Donev

Rossen Donev
Rossen Donev received his PhD degree in 1999 from the Institute of Molecular Biology, Bulgarian Academy of Sciences. He did postdoctoral training at Imperial Cancer Research Fund, UK (renamed after the merger with Cancer Research Campaign to Cancer Research UK, London Research Institute) and Cardiff University. In 2007 he was awarded a New Investigator Grant Award from the Medical Research Council (UK) to establish himself as an independent Principle Investigator. In 2010 Dr. Donev was appointed Senior Lecturer at Swansea University. In 2016 Dr. Donev joined MicroPharm Ltd (UK) where currently he is Head of Research. He has published more than 60 research papers, chaired scientific meetings and given invited plenary talks. Rossen Donev has consulted on projects related to development of treatments for neurodevelopmental disorders and cancer therapies. He serves as Editor-in-Chief of the Advances in Protein Chemistry and Structural Biology and on editorial board of several other journals. His research interests include signaling pathways involved in neuropsychiatric disorders and tumor escape from the immune system, and development of therapeutic strategies for their treatment. More recently he has focused on development of immunotherapeutics for non-systemic applications.

Affiliations and Expertise

Head of Research, MicroPharm Limited, UK

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