Translational Autoimmunity

Translational Autoimmunity

Challenges for Autoimmune Diseases

1st Edition - September 23, 2022

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  • Editor: Nima Rezaei
  • Paperback ISBN: 9780323853897

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Translational Autoimmunity: Challenges for Autoimmune Diseases, Fifth Edition addresses diagnostic approaches, therapeutic opportunities, and prognostic markers of different autoimmune diseases. This updated volume discusses autotoxicity, systems immunology, the prognostic significance of disease-specific autoantibodies, along with translational research to novel therapeutic policy in autoimmune diseases. From an introduction, to challenges and  insights on the systems immunology of infectious and autoimmune diseases, new targets of treatments, and the role of autoantibodies in diagnosis and evolution, this book provides insights on many challenges researchers and clinicians are facing.

Key Features

  • Describes challenges in the diagnosis, management and treatment of autoimmune diseases
  • Highlights major difficulties in the diagnosis and management of autoimmune diseases
  • Reflects important remediable deficiencies in current management
  • Meets the needs of basic scientists, clinicians and translational scientists and industry partners


Immunologists, Clinical immunologists, Endocrinologists, Microbiologists, Neurologists, Oncologists, Rheumatologists, Clinicians, research scientists, and industry partners

Table of Contents

  • 1. Introduction on Challenges for Autoimmune Diseases

    2. From horror autotoxicus to autoimmunity

    3. Flow cytometry in the diagnosis of autoimmune related lymphoproliferative disorder

    4. Autoantigens in atopic dermatitis: the characterization of autoantigens and their diagnostic value

    5. Current paradigms and challenges in vitiligo translational research

    6. The role of the kynurenine-pathway aryl hydrocarbon receptor axis in autoimmune diseases of the skin

    7. COVID-19 in Childhood and Phenotypes of Pediatric Inflammatory Multisystem Syndrome

    8. Challenges for epigenetics of periodontitis

    9. Neutrophil extracellular traps in autoimmunity, renal diseases, and transplantation

    10. Membranous nephropathy and the role of autoantibodies in its diagnosis and evolution

    11. Testicular immune tolerance and viral infections

    12. Ophthalmologic manifestations and management of systemic autoimmune diseases

    13. Challenges for diagnosis and treatment of primary biliary cholangitis

    14. Modelling autoimmune cholangiopathies as infectious disease

    15. Bullous skin diseases and epitope-spreading

    16. Dermatologic autoimmunity associated with immune checkpoints inhibitors

    17. Insights and strategies to promote immune tolerance in allogenic hematopoietic stem cell transplantation recipients

    18. The potential of cellular transplantation to harness autoimmunity and reverse clinical diabetes

Product details

  • No. of pages: 316
  • Language: English
  • Copyright: © Academic Press 2022
  • Published: September 23, 2022
  • Imprint: Academic Press
  • Paperback ISBN: 9780323853897

About the Editor

Nima Rezaei

Nima Rezaei is professor of immunology at Tehran University of Medical Sciences. He is a well-known scientists and researcher with over 1000 academic publications including papers and books. He is an expert researcher who has trained many students over the past decade.

Affiliations and Expertise

Professor of Clinical Immunology, Research Center for Immunodeficiencies, Children's Medical Center and Department of Immunology, School of Medicine, Tehran University of Medical Sciences; Network of Immunity in Infection, Malignancy and Autoimmunity (NIIMA), Universal Scientific Education and Research Network (USERN), Tehran, Iran

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