TRAIL, Volume 67

1st Edition

Hardcover ISBN: 9780127098678
eBook ISBN: 9780080522876
Imprint: Academic Press
Published Date: 7th May 2004
Page Count: 448
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Description

The discovery of TRAIL (TNF Related Apoptosis Inducing Ligand), also referred to as Apo-2, is in an era of intense research because TRAIL induces many cancer cells to undergo programmed cell death (apoptosis), while having no effect on normal cells. This important protein deserves extensive review at a formative time in the devlopement of our knowledge concerning its mechanism of action and the ways in which it can be used as a cancer chemotherapeutic agent. Consequently, this voume reviews the current status of research on TRAIL.

Key Features

Selected Contents:

  • Crystal Structure of RANK Ligand involved in bone metabolism
  • Promoter of TRAIL-R2 Gene
  • Monoclonal Antibodies against TRAIL
  • Modulation of TRAIL signaling complex
  • TRAIL in the airways
  • FLIP Protein and TRAIL-Induced Apoptosis
  • TRAIL and Ceramide
  • TRAIL and Viral Infection
  • TRAIL and Malignant Glioma

Readership

Molecular biologists, cellular biologists, & biochemists


Details

No. of pages:
448
Language:
English
Copyright:
© Academic Press 2004
Published:
Imprint:
Academic Press
eBook ISBN:
9780080522876
Hardcover ISBN:
9780127098678

Reviews

The discovery of TRAIL (TNF Related Apoptosis Inducing Ligand), also referred to as Apo-2, is in an era of intense research because TRAIL induces many cancer cells to undergo programmed cell death (apoptosis), while having no effect on normal cells. This important protein deserves extensive review at a formative time in the devlopement of our knowledge concerning its mechanism of action and the ways in which it can be used as a cancer chemotherapeutic agent. Consequently, this voume reviews the current status of research on TRAIL.