Total Synthesis of Bioactive Natural Products

Total Synthesis of Bioactive Natural Products

1st Edition - April 27, 2019

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  • Author: Goutam Brahmachari
  • eBook ISBN: 9780081028230
  • Paperback ISBN: 9780081028223

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Description

Total Synthesis of Bioactive Natural Products provides step-by-step guidelines for effectively synthesizing the most promising bioactive agents from a broad range of natural products. Beginning with a concise background that outlines the benefits and challenges faced in effective synthesis, the book goes on to provide individual outlines for approximately 100 of the most promising bioactive agents. Taking a logical, user-friendly approach, the systematic name, compound class, structure, natural source, pharmaceutical potential and synthetic routes for each structure are detailed, with clear illustrations throughout, making this book an essential and practical guide for anyone working with both synthesis and natural products.

Key Features

  • Provides individual outlines for the total synthesis of approximately 100 bioactive natural molecules
  • Outlines each step of the process in detail, with full experimental information supported by extensive schemes
  • Includes retrosynthetic analyses, reaction sequences and stereochemically crucial steps for each molecule

Readership

Natural products chemists, Synthetic chemists, Phytochemists, Medicinal chemists, Combinatorial chemists, Pharmaceutical Scientists, Plant Scientists, Manufacturers of natural products, Researchers in both academia and industry

Table of Contents

  • Aeruginosins 298-A and B
    Ageladine A
    (+)-Ainsliadimer A-(+)
    ()-Aiphanol
    (+)-Amphidinolide T1
    Ancistroealaine A and Ancistrotanzanine B
    ()-Andrographolide
    Anolignan A
    Anolignan B
    Antrocamphin A
    Arenamide A
    Atroviridin
    Bauhinoxepin J
    Beta-Lapachone
    Bombykol
    Bulbophylol-B
    Caminoside A
    (+)-Chaetocin
    Ciliatamides A and B
    Cylindol A
    Daedalin A
    6-Deoxypladienolide D
    7-Desmethoxyfusarentin and its methyl ether
    Etnangien
    (+)-Gliocladin B
    (+)-Harziphilone
    Hibarimicinone
    (±)-3-Hydroxy-beta-ionone
    Hyperforin
    Integric acid
    Jineol
    Karalicin
    ()-Kunstleramide
    (±)-Limonin
    Linderaspirone A and Bi-linderone
    Lucidone
    (±)-Marinopyrrole A
    Martefragin A
    ()-Melotenine A
    Microcin SF608
    Nemorosone
    Nicotlactone A
    ()-6-O-Desmethylantofine
    Oleocanthal
    (+)-3-Oxo--ionol
    Paecilomycin B
    Paecilomycine A 
    Pochonin A
    Rhinacanthin A
    Rubriflordilactone A
    (+)-Sattazolin
    Somocystinamide A
    ()-Stagonolide A
    (±)-Steenkrotin A
    Thiaplakortone A and its semi-synthetic derivatives
    Vinigrol
    Withaferin A
    Withanolide A
    (+)-Xylarenal A
    Xyolide

Product details

  • No. of pages: 350
  • Language: English
  • Copyright: © Elsevier 2019
  • Published: April 27, 2019
  • Imprint: Elsevier
  • eBook ISBN: 9780081028230
  • Paperback ISBN: 9780081028223

About the Author

Goutam Brahmachari

Goutam Brahmachari
Goutam Brahmachari, PhD, FRSC, is a professor of organic chemistry at Visva-Bharati University, Santiniketan, India. With more than 22 years of experience in both teaching and research, he has produced over 200 scientific publications, including original research papers, review articles, books, and invited book chapters in the field of natural products and synthetic organic chemistry. He has already authored/edited 25 books from the leading scientific publishers. Prof. Brahmachari serves several scientific bodies and received several awards and accolades for his contribution in both teaching and research, namely, Dr Kalam Best Teaching Faculty Award-2017, INSA (Indian National Science Academy) Teachers Award-2019, and CRSI (Chemical Research Society of India) Bronze Medal-2021 (contributions to research in chemistry). Prof. Brahmachari has been featured in the recently published World Ranking-2020 of the Top 2% Scientists (Organic Chemistry Category).

Affiliations and Expertise

Department of Chemistry, Visva-Bharati University, Santiniketan, India

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