Description

New developments in mass spectrometry have allowed routine identification and lowered limits of detection at levels only imagined a decade ago. Thousands of contaminants and residues in the food supply and the environment are now being reported. Between 2005 and 2010, more than 5,000 publications covering TOF-MS and environmental and food analysis were published, showing the importance of the technique in these applications.

This book covers the basic principles of method development in GC- and LC-TOF-MS as well as the main operational parameters related to TOF-MS. The second part focuses on the relevant environmental applications, including quality control aspects as well as data collection. The third part is devoted to relevant applications in food analysis, including validation procedures for screening analysis as well as relevant databases.

Key Features

  • Outlines basic concepts and principles of gas and liquid chromatography TOF-MS and its application in food analysis
  • Includes quality control and data collection techniques
  • Focuses on environmental implications and safety concerns

Readership

Analytical chemists, food chemists, environmental scientists

Table of Contents

  • Dedication
  • Series Page
  • Volume in the Series
  • Contributors to Volume 58
  • Series Editor’s Preface
  • Volume Editor’s Preface
  • Chapter 1 Application of HPLC–TOF-MS and HPLC–QTOF-MS/MS for Pesticide Residues Analysis in Fruit and Vegetable Matrices
    • 1 Introduction and Scope
    • 2 Advantages of the Accurate Mass
    • 3 Accurate Mass Databases and Automatic Searching
    • 4 Applications of HPLC–TOF-MS for Multiresidue Analysis of Pesticides in Fruits and Vegetables
    • 5 Multiresidue Methods Based on Sequential TOF-MS and QTOF-MS/MS.
    • 6 Conclusions and Future Trends
  • Chapter 2 Chemical Evaluation of Water Treatment Processes by LC–(Q)TOF-MS
    • 1 Introduction
    • 2 TPs in Wastewater Treatments
    • 3 Strategies for Identification and Structural Elucidation of TPs by LC–(Q)TOF-MS: Practical Aspects
    • 4 Selected Applications of LC–(Q)TOF-MS in Water Treatment Processes: Transformation Pathways
    • 5 Conclusions
  • Chapter 3 Selected Applications of Accurate Mass Determinations Using LC-TOF for Toxic Compounds in Products of Animal Origin
    • 1 Accurate Mass Determinations
    • 2 Case Study 1: Injectable Solution of Oxytetracycline Contaminated with a Suspect Sulfonamide
    • 3 Case Study 2: Green-Eyed Dog and Rhodamine Dye
    • 4 Case Study 3: Thirty-Six Dead Birds and Contaminated Seeds
    • 5 Overall Considerations and Conclusions
  • Chapter 4 High Mass Resolution Versus MS/MS
    • 1 Introduction
    • 2 Basic Principle of Modern HRMS Instruments
    • 3 Selectivity
    • 4 Sensitivity
    • 5 Quantitative Performance
    • 6 Confirmation
    • 7 Identification of Unknowns
    • 8 Comprehensiveness of Detection
    • 9 Conclusion
  • Chapter 5 Time-of-Flight Mass Spectrometry Versus Orbitrap-Based Mass Spe

Details

No. of pages:
460
Language:
English
Copyright:
© 2012
Published:
Imprint:
Elsevier
Electronic ISBN:
9780444538116
Print ISBN:
9780444538109

About the editor