Thirst and Sodium Appetite  - 1st Edition - ISBN: 9780123043009, 9780323157049

Thirst and Sodium Appetite

1st Edition

Physiological Basis

Authors: Sebastian Grossman
eBook ISBN: 9780323157049
Imprint: Academic Press
Published Date: 28th June 1990
Page Count: 300
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Thirst and Sodium Appetite: Physiological Basis describes the phenomenon of thirst and the mechanisms that define the need for water. Thirst and appetite has generated much study and research about the physiological, endocrinological, and pharmacological mechanisms that influence water intake. However, in this book, other concerns have been emphasized, such as the significance of brain mechanisms in the subject matter. This book, consisting of 11 chapters, starts with a basic description of thirst then to an analysis of basic physiological mechanisms that determine water intake. Another topic also discussed in this book is various experimental paradigms that resulted to the dual-depletion theory of thirst. The neuroanatomical, neuroendocrinological, and neuropharmacological brain mechanisms are covered in three chapters of this book. These brain mechanisms respond to different peripheral signals that stimulate the thirst. The final chapters are dedicated to sodium appetite. Although it has lesser literature than thirst has, there have been significant developments in the understanding of the role of sodium appetite in extracellular thirst. The last chapter reviews the questions that has kept investigators at bay and recommends direction of where future research may go.

Table of Contents

Preface 1 The Nature of Thirst Introduction The Sensation of Thirst Oral Influences Interactions between Oral Sensations and Thirst Ad Libitum Drinking Review and Conclusions 2 The Body's Water Stores Cellular and Extracellular Compartments The Exchange of Body Fluids The Role of the Kidney Effects of Water Deprivation The Dual Depletion Theory of Thirst Review and Conclusions 3 Cellular Dehydration Thirst Introduction Water Intake after Different Hypertonic Solutions Renal Effects of Hypertonicity of Body Fluids Cellular Rehydration as a Satiety Signal Receptor Mechanisms for Cellular Thirst Review and Conclusions 4 Extracellular Thirst I: Hypovolemia, Hyponatremia, and Hypotension Hypovolemia Hemorrhage Hyponatremia Experimental Edema Caval Ligation Beta-Adrenergic Thirst Mechanical Stimulation of Atrial Receptors Atrial Natriuretic Factor Review and Conclusions 5 Extracellular Thirst II: The Renin-Angiotensin System Introduction The Role of Angiotensin in Thirst The Dipsogenic Properties of Renin and Angiotensin Extracellular Thirst after Blockade of the Renin-Angiotensin System Peptide Effects Related to A-II Review and Conclusions 6 Satiety Patterns of Drinking Preabsorptive Factors Postabsorptive Factors Relative Contribution of Cellular and Extracellular Satiety Signals Review and Conclusions 7 Brain Mechanisms of Thirst: Anatomical Considerations Historical Perspectives Hypothalamus Zona Incerta Lateral Preoptic Area Anteroventral Third Ventricle (AV3V) Medial Preoptic Area OVLT and Nucleus Medianus Subfornical Organ Septal Area Review and Conclusions 8 Brain Mechanisms II: Intracranial Angiotensin Dipsogenic Effects


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© Academic Press 1990
Academic Press
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About the Author

Sebastian Grossman

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