The Vitamins

The Vitamins

Fundamental Aspects in Nutrition and Health

6th Edition - February 24, 2022

Write a review

  • Authors: Gerald Combs, Jr., James McClung
  • Hardcover ISBN: 9780323904735
  • eBook ISBN: 9780323918268

Purchase options

Purchase options
Available
DRM-free (EPub, PDF)
Sales tax will be calculated at check-out

Institutional Subscription

Free Global Shipping
No minimum order

Description

The Vitamins: Fundamental Aspects in Nutrition and Health, Sixth Edition presents both overviews and in-depth discussions of the sources, chemistry, metabolism and functions of these essential nutrients in physiology and health. Sections cover perspectives (history of discovery, general properties and impacts), individual Vitamins (their respective chemistries, metabolism), and their dietary sources and global needs. In addition, the inclusion and interpretation of recent clinical research findings relevant to all vitamins, particularly vitamins A, D, E, K, C, thiamin, folate and vitamin B12 is included, along with an expanded discussion on single-carbon metabolism), implications to neuropathies, and more.

Key Features

  • Presents complete information about vitamins in a format useful as both a teaching text and desk reference
  • Includes coverage of vitamin-related topics not typically found in general nutrition texts (e.g., enteric microbial biosynthesis of vitamins, global prevalence of deficiencies, diagnosing ‘silent’ asymptomatic vitamin deficiencies, histories of vitamin discoveries)
  • Contains useful appendices of key reference information (e.g., vitamin requirements of humans and animals, vitamin contents of foods, sources of vitamin information)

Readership

Upper level undergraduate and graduate students studying micronutrients in nutrition programs, researchers in nutrition, food science, pharmacology, endocrinology, public health, and epidemiology; dieticians, clinicians

Table of Contents

  • Cover image
  • Title page
  • Table of Contents
  • Copyright
  • Dedication
  • Preface to the Sixth Edition
  • Part I. Perspectives on the vitamins in nutrition
  • Chapter 1. What is a vitamin?
  • Anchoring concepts
  • Learning objectives
  • Vocabulary
  • 1. Thinking about vitamins
  • 2. Vitamin: a revolutionary concept
  • 3. An operating definition
  • 4. The recognized vitamins
  • 5. Chapter quiz
  • Chapter 2. Discovery of the vitamins
  • Anchoring concepts
  • Learning objectives
  • Vocabulary
  • 1. Emergence of nutrition as a science
  • 2. Processes of discovery in nutritional science
  • 3. The empirical phase of vitamin discovery
  • 4. The experimental phase of vitamin discovery
  • 5. The vitamine theory
  • 6. Elucidation of the vitamins
  • 7. Vitamin terminology
  • 8. Other factors sometimes called vitamins
  • 9. Modern history of the vitamins
  • 10. Chapter quiz
  • Chapter 3. General properties of vitamins
  • Anchoring concepts
  • Learning objectives
  • Vocabulary
  • 1. Vitamin nomenclature
  • 2. Chemical and physical properties of the vitamins
  • 3. Physiological utilization of the vitamins
  • 4. Metabolism of the vitamins
  • 5. Metabolic functions of the vitamins
  • 6. Vitamin bioavailability
  • 7. Vitamin analysis
  • 8. Chapter quiz
  • Chapter 4. Vitamin deficiency
  • Anchoring concepts
  • Learning objectives
  • Vocabulary
  • 1. The concept of vitamin deficiency
  • 2. Clinical manifestations of vitamin deficiencies
  • 3. Biochemical lesions of vitamin deficiencies
  • 4. Diagnosing vitamin deficiencies
  • 5. Contexts of vitamin deficiencies
  • 6. Effective interventions
  • 7. Chapter quiz
  • Part II. The individual vitamins
  • Chapter 5. Vitamin A
  • Anchoring concepts
  • Learning objectives
  • Vocabulary
  • 1. Significance of vitamin A
  • 2. Properties of vitamin A
  • 3. Sources of vitamin A
  • 4. Vitamin A absorption
  • 5. Vitamin A transport
  • 6. Vitamin A metabolism
  • 7. Metabolic functions of vitamin A
  • 8. Biomarkers of vitamin A status
  • 9. Vitamin A requirements
  • 10. Vitamin A deficiency
  • 11. Other deficiency signs in humans
  • 12. Other roles of vitamin A in health and disease
  • 13. Vitamin A toxicity
  • 14. Case studies
  • 15. Chapter quiz
  • Chapter 6. Vitamin D
  • Anchoring concepts
  • Learning objectives
  • Vocabulary
  • 1. Significance of vitamin D
  • 2. Properties of vitamin D
  • 3. Sources of vitamin D
  • 4. Vitamin D absorption
  • 5. Vitamin D transport
  • 6. Vitamin D metabolism
  • 7. Metabolic functions of vitamin D
  • 8. Biomarkers of vitamin D status
  • 9. Vitamin D requirements
  • 10. Vitamin D deficiency
  • 11. Other roles of vitamin D in health and disease
  • 12. Vitamin D toxicity
  • 13. Case studies
  • 14. Chapter quiz
  • Chapter 7. Vitamin E
  • Anchoring concepts
  • Learning objectives
  • Vocabulary
  • 1. Significance of vitamin E
  • 2. Properties of vitamin E
  • 3. Sources of vitamin E
  • 4. Vitamin E absorption
  • 5. Vitamin E
  • 6. Vitamin E metabolism
  • 7. Oxidative shortening of the phytyl side chain
  • 8. Metabolic functions of vitamin E
  • 9. Biomarkers of vitamin E status
  • 10. Vitamin E requirements
  • 11. Vitamin E deficiency
  • 12. Vitamin E deficiency signs in humans
  • 13. Vitamin E deficiency signs in animals
  • 14. Other roles of vitamin E in health and disease
  • 15. Vitamin E toxicity
  • 16. Case studies
  • 17. Chapter quiz
  • Chapter 8. Vitamin K
  • Anchoring concepts
  • Learning objectives
  • Vocabulary
  • 1. Significance of vitamin K
  • 2. Properties of vitamin K
  • 3. Sources of vitamin K
  • 4. Vitamin K absorption
  • 5. Vitamin K
  • 6. Vitamin K metabolism
  • 7. Metabolic functions of vitamin K
  • 8. Biomarkers of vitamin K status
  • 9. Vitamin K requirements
  • 10. Vitamin K deficiency
  • 11. Other roles of vitamin K in health and disease
  • 12. Vitamin K toxicity
  • 13. Case studies
  • 14. Chapter quiz
  • Chapter 9. Vitamin C
  • Anchoring concepts
  • Learning objectives
  • Vocabulary
  • 1. Significance of vitamin C
  • 2. Properties of vitamin C
  • 3. Sources of vitamin C
  • 4. Vitamin C
  • 5. Vitamin C
  • 6. Vitamin C
  • 7. Metabolic functions of vitamin C
  • 8. Biomarkers of vitamin C status
  • 9. Vitamin C requirements
  • 10. Vitamin C deficiency
  • 11. Other roles of vitamin C in health and disease
  • 12. Vitamin C toxicity
  • 13. Case studies
  • 14. Chapter quiz
  • Chapter 10. Thiamin
  • Anchoring concepts
  • Learning objectives
  • Vocabulary
  • 1. Significance of thiamin
  • 2. Properties of thiamin
  • 3. Thiamin chemistry
  • 4. Sources of thiamin
  • 5. Thiamin absorption
  • 6. Thiamin transport
  • 7. Thiamin metabolism
  • 8. Metabolic functions of thiamin
  • 9. Biomarkers of thiamin status
  • 10. Thiamin requirements
  • 11. Thiamin deficiency
  • 12. Signs in humans
  • 13. Other roles of thiamin in health and disease
  • 14. Thiamin toxicity
  • 15. Case studies
  • 16. Chapter quiz
  • Chapter 11. Riboflavin
  • Anchoring concepts
  • Learning objectives
  • Vocabulary
  • 1. Significance of riboflavin
  • 2. Properties of riboflavin
  • 3. Sources of riboflavin
  • 4. Riboflavin absorption
  • 5. Riboflavin transport
  • 6. Riboflavin metabolism
  • 7. Metabolic functions of riboflavin
  • 8. Biomarkers of riboflavin status
  • 9. Riboflavin requirements
  • 10. Riboflavin deficiency
  • 11. Other roles of riboflavin in health and disease
  • 12. Riboflavin toxicity
  • 13. Case study
  • 14. Chapter quiz
  • Chapter 12. Niacin
  • Anchoring concepts
  • Learning objectives
  • Vocabulary
  • 1. Significance of niacin
  • 2. Properties of niacin
  • 3. Sources of niacin
  • 4. Niacin absorption
  • 5. Niacin transport
  • 6. Niacin metabolism
  • 7. Metabolic functions of niacin
  • 8. Biomarkers of niacin status
  • 9. Niacin requirements
  • 10. Niacin deficiency
  • 11. Other roles of niacin in health and disease
  • 12. Niacin toxicity
  • 13. Case studies
  • 14. Chapter quiz
  • Chapter 13. Vitamin B6
  • Anchoring concepts
  • Learning objectives
  • Vocabulary
  • 1. Significance of vitamin B6
  • 2. Properties of vitamin B6
  • 3. Sources of vitamin B6
  • 4. Vitamin B6 absorption
  • 5. Vitamin B6 transport
  • 6. Vitamin B6 metabolism
  • 7. Metabolic functions of vitamin B6
  • 8. Biomarkers of vitamin B6 status
  • 9. Vitamin B6 requirements
  • 10. Vitamin B6 deficiency
  • 11. Other roles of vitamin B6 in health and disease
  • 12. Vitamin B6 toxicity
  • 13. Case studies
  • 14. Chapter quiz
  • Chapter 14. Biotin
  • Anchoring concepts
  • Learning objectives
  • Vocabulary
  • 1. Significance of biotin
  • 2. Properties of biotin
  • 3. Sources of biotin
  • 4. Biotin absorption
  • 5. Biotin
  • 6. Metabolic functions of biotin
  • 7. Biomarkers of biotin status
  • 8. Biotin requirements
  • 9. Biotin deficiency
  • 10. Other roles of biotin in health and disease
  • 11. Biotin toxicity
  • 12. Case studies
  • 13. Chapter quiz
  • Chapter 15. Pantothenic acid
  • Anchoring concepts
  • Learning objectives
  • Vocabulary
  • 1. Significance of pantothenic acid
  • 2. Properties of pantothenic acid
  • 3. Sources of pantothenic acid
  • 4. Pantothenic acid absorption
  • 5. Pantothenic acid transport
  • 6. Pantothenic acid metabolism
  • 7. Metabolic functions of pantothenic acid
  • 8. Biomarkers of pantothenic acid status
  • 9. Pantothenic acid requirements
  • 10. Pantothenic acid deficiency
  • 11. Other roles of pantothenic acid in health and disease
  • 12. Pantothenic acid toxicity
  • 13. Case studies
  • 14. Chapter quiz
  • Chapter 16. Folate
  • Anchoring concepts
  • Learning objectives
  • Vocabulary
  • 1. Significance of folate
  • 2. Properties of folate
  • 3. Sources of folate
  • 4. Folate absorption
  • 5. Folate transport
  • 6. Folate metabolism
  • 7. Metabolic functions of folate
  • 8. Biomarkers of folate status
  • 9. Folate requirements
  • 10. Folate deficiency
  • 11. Other roles of folate in health and disease
  • 12. Folate toxicity
  • 13. Case studies
  • 14. Chapter quiz
  • Chapter 17. Vitamin B12
  • Anchoring concepts
  • Learning objectives
  • Vocabulary
  • 1. Significance of vitamin B12
  • 2. Properties of vitamin B12
  • 3. Sources of vitamin B12
  • 4. Vitamin B12 absorption
  • 5. Vitamin B12 transport
  • 6. Vitamin B12 metabolism
  • 7. Metabolic functions of vitamin B12
  • 8. Biomarkers of vitamin B12 status
  • 9. Vitamin B12 requirements
  • 10. Vitamin B12 deficiency
  • 11. Other roles of vitamin B12 in health and disease
  • 12. Vitamin B12 toxicity
  • 13. Case studies
  • 14. Chapter quiz
  • Chapter 18. Quasi-vitamins
  • Anchoring concepts
  • Learning objectives
  • Vocabulary
  • 1. Is the list of vitamins complete?
  • Conditionally essential nutrients
  • 3. Carnitine
  • 4. myo-Inositol
  • 5. Ubiquinones
  • 6. Lipoic acid
  • Beneficial bioactive factors
  • 8. Flavonoids
  • 9. Unidentified factors
  • 10. Case studies
  • 11. Chapter quiz
  • Part III. Using current knowledge of the vitamins
  • Chapter 19. Sources of the vitamins
  • Anchoring concepts
  • Learning objectives
  • Vocabulary
  • 1. Vitamins in foods and feedstuffs
  • 2. Vitamin bioavailability
  • 3. Vitamin losses in foods
  • 4. Adding vitamins to foods
  • 5. Biofortification
  • 6. Vitamin labeling of foods
  • 7. Vitamins in human diets
  • 8. Vitamin supplementation
  • 9. Vitamins in livestock feeding
  • 10. Case study
  • 11. Chapter quiz
  • Chapter 20. Assessing vitamin status
  • Anchoring concepts
  • Learning objectives
  • Vocabulary
  • 1. Nutritional assessment
  • 2. Biomarkers of vitamin status
  • 3. Vitamin status of human populations
  • 4. Global undernutrition
  • 5. Chapter quiz
  • Chapter 21. Vitamin needs
  • Anchoring concepts
  • Learning objectives
  • Vocabulary
  • 1. Dietary standards for vitamins
  • 2. Vitamin allowances for humans
  • 3. Vitamin allowances for animals
  • 4. Case study
  • 5. Chapter quiz
  • Chapter 22. Vitamin safety
  • Anchoring concepts
  • Learning objectives
  • Vocabulary
  • 1. Uses of vitamins above required levels
  • 2. Safe intakes of vitamins
  • 3. Hypervitaminoses
  • 4. Case studies
  • 5. Chapter quiz
  • Appendix A
  • Appendix B. Original reports used for case studies
  • Appendix C. A core of current vitamin literature
  • Appendix D. Vitamin contents of foods (units per 100 g edible portion)
  • Appendix E. Vitamin contents of feedstuffs (units per kg)
  • Appendix F. 20 Questions to examine vitamin knowledge
  • Index

Product details

  • No. of pages: 774
  • Language: English
  • Copyright: © Academic Press 2022
  • Published: February 24, 2022
  • Imprint: Academic Press
  • Hardcover ISBN: 9780323904735
  • eBook ISBN: 9780323918268

About the Authors

Gerald Combs, Jr.

Gerald F. Combs, Jr. is an internationally recognized leader in nutrition, particularly in the areas of micronutrient functions, diet and cancer prevention, and sustainable food systems. He has conducted research ranging from fundamental studies with cultured cells and animal models to human metabolic and clinical investigations, including studies in China, Bangladesh, Costa Rica and Malawi. He has lectured in some 30 countries and published more than 350 scientific papers and reviews, and 15 books, including six editions of The Vitamins: Fundamental Aspects in Nutrition and Health. He received his graduate training in nutritional biochemistry at Cornell University, where he later served on that faculty for 29 years before being named Director of the USDA Human Nutrition Research Center in Grand Forks ND from 2020-2015. He presently is a Senior Scientist at the Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University in Boston.

Affiliations and Expertise

Professor, Nutrition Emeritus, Division of Nutritional Sciences, Cornell University, Ithaca, NY, USA

James McClung

James P. McClung completed his B.S. and M.S. degrees at the University of New Hampshire, and his doctoral degree at Cornell University. He completed a National Research Council post-doctoral fellowship prior to assuming a career in Nutrition Science with the Department of Defense. Dr. McClung’s research has focused on micronutrient nutrition at both the basic and applied levels and has led to the fielding of applied solutions for the optimization of human health and performance. He is an active member of a number of professional societies, including the American Society for Nutrition. He has authored or co-authored over 100 peer reviewed manuscripts, technical reports, and book chapters, and has served on the editorial boards of a number of leading international nutrition journals. Dr. McClung has co-authored the two most recent editions of The Vitamins: Fundamental Aspects in Nutrition and Health.

Affiliations and Expertise

Nutritional biochemist, Westborough, Massachusetts, USA

Ratings and Reviews

Write a review

There are currently no reviews for "The Vitamins"