The third edition of this bestselling text will again provide the latest coverage of the biochemistry and physiology of vitamins and vitamin-like substances. Extensively revised and expanded on the basis of recent research findings with enlarged coverage of health effects of vitamin-like factors, it is ideally suited for students and an important reference for anyone interested in nutrition, food science, animal science or endocrinology. It contains a cohesive and well-organized presentation of each of the vitamins, as well as the history of their discoveries and current information about their roles in nutrition and health.

Key Features

NEW TO THIS EDITION: *Includes approximately 30% new material *Substantial updates have been made to chapters on vitamins A, C, E, K, folate, and the quasi-vitamins *Provides checklists of systems affected by vitamin deficiencies and food sources of vitamins *Key concepts, learning objectives, vocabulary,case studies, study questions and additional reading lists are included making this ideally suited for students * Thoroughly updated with important recent research results, including citations to key reports, many added tables and several new figures. *Addition of Health and Nutrition Examination Survey (HANES III) data *Updated Dietary Reference Values


Students and health professionals, also researchers in food science, veterinary and animal sciences

Table of Contents

Part I. Perspectives on the Vitamins in Nutrition 1. What is a Vitamin? a. Thinking about Vitamins b. Vitamin: a Revolutionary Concept c. A Operating Definition of a Vitamin d. The Recognized Vitamins e. Study Questions and Exercises 2. Discovery of the Vitamins a. The Emergence of Nutrition as a Science b. The Process of Discovery in Nutritional Science c. The Empirical Phase of Vitamin Discovery d. The Experimental Phase of Vitamin Discovery e. The Vitamine Theory f. Elucidation of the Vitamins g. Vitamin Terminology h. Other factors Sometimes Called Vitamins i. The Modern History of the Vitamins j. The Impact of the “Omics” Revolution in Biology k. Study questions and Exercises l. Recommended Reading 3. Chemical and Physiological Properties of Vitamins a. Chemical and Physical Properties of Vitamins b. Vitamin A c. Vitamin D d. Vitamin E e. Vitamin K f. Vitamin C g. Thiamin h. Riboflavin i. Niacin j. Vitamin B6 k. Biotin l. Pantothenic Acid m. Folate n. Vitamin B12 o. General Properties of Vitamins p. Physiological Properties of Vitamins q. Metabolism of Vitamins r. Study Questions and Exercises s. Recommended Reading 4. Vitamin Deficiency a. The Concept of Vitamin Deficiency b. The Many Causes of Vitamin Deficiency c. Clinical Manifestations of Vitamin Deficiencies d. Vitamin Deficiency Diseases: Manifestations of Biochemical Lesions


No. of pages:
© 2007
Academic Press
Print ISBN:
Electronic ISBN:

About the editor

Gerald Combs, Jr.

Gerald F. Combs, Jr., Ph.D., is a Emeritus Professor of Nutrition at Cornell University. His specialties are the nutritional biochemistry of trace elements and vitamins, clinical intervention studies, and the linkages of agriculture and human health in national development. He has authored or co-authored 279 publications, including two major reference books.

Affiliations and Expertise

Professor Emeritus, Division of Nutritional Sciences, Cornell University, Ithaca, New York, U.S.A.


PRAISE FOR THE FIRST EDITION: "It was a pleasure to read this magnificent book that can be used for teaching and as a desk reference. In short, this is the premier textbook in vitamins and may be used at both the graduate and undergraduate levels." -JOURNAL OF OPTIMAL NUTRITION "This text would be useful for anyone teaching a course about vitamins." -FOOD TECHNOLOGY "The organization of the book is a unique and useful approach to presenting material. Students will find the formatting of individual chapters extremely useful. This is an excellent learning textbook for an undergraduate or early graduate course on the vitamins." -JOURNAL OF NUTRITION EDUCATION "The book is obviously valuable to those teaching or using information associated with vitamins. I also recommend the book to other teachers as a way of presenting material to students to learn rather than memorize." -JOURNAL OF VETERINARY MEDICAL EDUCATION "The strength of this book is the clear description of the chemistry of each vitamin and related compounds and of the biochemistry and metabolic functions in the body. For those who want to build their knowledge of the vitamins on a chemical and biochemical base, this book will prove excellent." -AUSTRALIAN VETERINARY JOURNAL