The Structure of Mitochondria

The Structure of Mitochondria

1st Edition - January 1, 1974

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  • Author: E. A. Munn
  • eBook ISBN: 9781483272603

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The Structure of Mitochondria provides an extensive account of the structure of mitochondria. This book illustrates the variety of mitochondrial structure revealed by electron microscopy of intact cells. Organized into nine chapters, this book begins with an overview of the application of electron microscopy to the study of the structure of cells and their mitochondria. This text then explains the short-term changes of the type revealed by phase contrast microscopy of living cells. Other chapters consider the rationale behind the procedures generally employed for the isolation of mitochondria and other sub-cellular components. This book discusses as well the important component of mitochondria. The final chapter describes the interesting similarities of mitochondria, chloroplasts, and bacteria and the bearing these have on the concept about the way in which the relationships between mitochondria and the rest of the eukaryotic cell have evolved. This book is a valuable resource for biologists, physiologists, and bacteriologists.

Table of Contents

  • Chapter 1 Variety in the Structure of Mitochondria in Situ

    Shape of Mitochondria In Situ

    Shape and Organization of Cristae

    Surface Area of the Mitochondrial Membranes

    Arrangement of Mitochondria in The Cell

    Mitochondrial Inclusions

    Chapter 2 Changes in Structure of Mitochondria In Situ

    Structural Changes During Development and Differentiation

    Structural Changes During Gametogenesis

    Structural Changes Due to Changes in Diet

    Structural Changes Due to Changes in Environment and Physiological State

    Structural Change in Yeast Mitochondria

    Changes in Structure Associated With Clinical Disorders

    Chapter 3 The Structure of Isolated Mitochondria

    Isolation of Mitochondria

    Structure of Intact Isolated Mitochondria

    Changes in Mitochondrial Structure in Relation to Changes in Osmotic Pressure

    Changes in Mitochondrial Structure Induced by "swelling Agents"

    Reversal of Large Amplitude Swelling

    Structures Unique to Isolated Mitochondria

    Structure of Disrupted Mitochondria

    Process of Fragmentation of Inner Membranes

    Chapter 4 Chemical Composition, Part 1: Proteins


    Nonhaem Iron Protein

    NADPH-Nonhaem Iron Protein Reductase

    Electron Transferring Flavoprotein

    Calcium Carrier

    Structural Protein(S) and Core Protein

    Peptide Chain Elongation Factors

    Coupling Factors


    Chapter 5 Chemical Composition, Part 2: Lipids, Metal Ions, Nucleotides, etc.


    Ubiquinones (Coenzymes Q)

    Metal Ions



    Other Anions




    Chapter 6 Structure and Functional Organization of the Mitochondrial Membranes

    Structure of the Mitochondrial Membranes

    Role of Lipids in the Structure and Activity of the Inner Membrane

    Mitochondrial Structure and the Generation of ATP

    Long-Term Stability of Mitochondrial Structure

    Mitochondrial Ribosomes

    The Problem of the Assembly of Mitochondria

    Chapter 7 Structural Aspects of Metabolic Pathways (Compartmentation)

    The Enzymes of the Tricarboxylic Acid Cycle

    The Enzymes Involved in Amino Acid Metabolism

    The Enzymes for Metabolism of Fatty Acids

    Transport Through the Inner Membrane

    Chapter 8 Relationships Between Mitochondrial Structure, Metabolic Control and Ion Transport


    Structure in Relation to Metabolic Steady State

    Oscillatory Changes in Mitochondrial Structure

    Effect of Composition of Suspending Medium on Metabolically Related Structural Changes

    The Effects of ADP, DNP and Phosphate on Mitochondrial Structure

    The Effects of Divalent Cations on Mitochondrial Structure

    Metabolically Related Structural Changes of Mitochondria In Situ

    The Significance of the Changes in the Internal Organization of Isolated Mitochondria

    Chapter 9 Mitochondria, Chloroplasts and Bacteria

    Mitochondria and Chloroplasts

    Mitochondria and Bacteria

    Evolutionary Origin of Mitochondria


    Author Index

    Subject Index

Product details

  • No. of pages: 480
  • Language: English
  • Copyright: © Academic Press 1974
  • Published: January 1, 1974
  • Imprint: Academic Press
  • eBook ISBN: 9781483272603

About the Author

E. A. Munn

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