The Structure of Mitochondria - 1st Edition - ISBN: 9780125101509, 9781483272603

The Structure of Mitochondria

1st Edition

Authors: E. A. Munn
eBook ISBN: 9781483272603
Imprint: Academic Press
Published Date: 1st January 1974
Page Count: 480
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The Structure of Mitochondria provides an extensive account of the structure of mitochondria. This book illustrates the variety of mitochondrial structure revealed by electron microscopy of intact cells.

Organized into nine chapters, this book begins with an overview of the application of electron microscopy to the study of the structure of cells and their mitochondria. This text then explains the short-term changes of the type revealed by phase contrast microscopy of living cells. Other chapters consider the rationale behind the procedures generally employed for the isolation of mitochondria and other sub-cellular components. This book discusses as well the important component of mitochondria. The final chapter describes the interesting similarities of mitochondria, chloroplasts, and bacteria and the bearing these have on the concept about the way in which the relationships between mitochondria and the rest of the eukaryotic cell have evolved.

This book is a valuable resource for biologists, physiologists, and bacteriologists.

Table of Contents

Chapter 1 Variety in the Structure of Mitochondria in Situ

Shape of Mitochondria In Situ

Shape and Organization of Cristae

Surface Area of the Mitochondrial Membranes

Arrangement of Mitochondria in The Cell

Mitochondrial Inclusions

Chapter 2 Changes in Structure of Mitochondria In Situ

Structural Changes During Development and Differentiation

Structural Changes During Gametogenesis

Structural Changes Due to Changes in Diet

Structural Changes Due to Changes in Environment and Physiological State

Structural Change in Yeast Mitochondria

Changes in Structure Associated With Clinical Disorders

Chapter 3 The Structure of Isolated Mitochondria

Isolation of Mitochondria

Structure of Intact Isolated Mitochondria

Changes in Mitochondrial Structure in Relation to Changes in Osmotic Pressure

Changes in Mitochondrial Structure Induced by "swelling Agents"

Reversal of Large Amplitude Swelling

Structures Unique to Isolated Mitochondria

Structure of Disrupted Mitochondria

Process of Fragmentation of Inner Membranes

Chapter 4 Chemical Composition, Part 1: Proteins


Nonhaem Iron Protein

NADPH-Nonhaem Iron Protein Reductase

Electron Transferring Flavoprotein

Calcium Carrier

Structural Protein(S) and Core Protein

Peptide Chain Elongation Factors

Coupling Factors


Chapter 5 Chemical Composition, Part 2: Lipids, Metal Ions, Nucleotides, etc.


Ubiquinones (Coenzymes Q)

Metal Ions



Other Anions




Chapter 6 Structure and Functional Organization of the Mitochondrial Membranes

Structure of the Mitochondrial Membranes

Role of Lipids in the Structure and Activity of the Inner Membrane

Mitochondrial Structure and the Generation of ATP

Long-Term Stability of Mitochondrial Structure

Mitochondrial Ribosomes

The Problem of the Assembly of Mitochondria

Chapter 7 Structural Aspects of Metabolic Pathways (Compartmentation)

The Enzymes of the Tricarboxylic Acid Cycle

The Enzymes Involved in Amino Acid Metabolism

The Enzymes for Metabolism of Fatty Acids

Transport Through the Inner Membrane

Chapter 8 Relationships Between Mitochondrial Structure, Metabolic Control and Ion Transport


Structure in Relation to Metabolic Steady State

Oscillatory Changes in Mitochondrial Structure

Effect of Composition of Suspending Medium on Metabolically Related Structural Changes

The Effects of ADP, DNP and Phosphate on Mitochondrial Structure

The Effects of Divalent Cations on Mitochondrial Structure

Metabolically Related Structural Changes of Mitochondria In Situ

The Significance of the Changes in the Internal Organization of Isolated Mitochondria

Chapter 9 Mitochondria, Chloroplasts and Bacteria

Mitochondria and Chloroplasts

Mitochondria and Bacteria

Evolutionary Origin of Mitochondria


Author Index

Subject Index


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© Academic Press 1974
Academic Press
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About the Author

E. A. Munn

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