The Spleen and Some of Its Diseases

The Spleen and Some of its Diseases provides information pertinent to the fundamental aspects of the spleen. This book discusses the role that spleen plays in the etiology of diseases whose most obvious symptoms are evoked by associated or consecutive affections of other organs. Organized into 14 chapters, this book begins with an overview of the anatomy of the spleen, which is entirely covered with peritoneum and is situated behind the fundus of the stomach. This text then describes the first recorded case of splenectomy. Other chapters consider the effect of splenectomy in man and animals upon the general health, upon the blood, and upon the various tissues. This book discusses as well the biochemical investigations upon the spleen and upon the metabolic activities of the body. The final chapter deals with the determination of the functional capacity of all the various organs. This book is a valuable resource for surgeons and physicians.

I.-Anatomy of the Spleen

Relations

Peritoneal Attachments

Blood-Supply

Surface Markings

Significance of Anatomical Features

Occasional Absence

II.-The Surgery of the Spleen

History

Association of Spleen with Laughter, and with Speed in Running

Early Records of Splenectomy

Experimental Observations

Cases of Absent Spleen

Splenectomy in Modern Times

III.-On the Functions of the Spleen

Brief Consideration of the Minute Anatomy and Physiology of the Spleen and Liver

Lines of Inquiry and Research

Results of Splenectomy in Animals

Questions Suggested Thereby

Connections of the Spleen with Other Organs

The Spleen as a Member of the Hemopoietic System

Reticulo-endothelial System

Digestive System

Sympathico-endocrine System

IV.-The Pathology of Splenic Diseases

Pathological Changes Grouped according to Affinities between Causal Agents and Parts of Spleen-Liver System Affected—Varieties of Toxins Entering or Leaving Spleen, and Their Actions

V.-The Clinical and Associated Phenomena in Splenic Disease

Anemia

Jaundice

Petechial Hemorrhages

Muscular Weakness

Pyrexia

Splenomegaly

Leucocytosis

Spleen and Hncmorrhagic Diathesis

Urobilin in the Urine

VI.-Pernicious Anemia (Addison's Anemia, Idiopathic Anemia)

History

'Primary' and 'Secondary' Misleading as Applied to Anemia

The Blood in Anemia

Pathology of Pernicious Anemia

Source of Toxin

Important Signs and Symptoms

Treatment by Splenectomy

VII.-Leukemia

History

Development of Science of Hematology

Pathology

Symptoms

Acute Leukemia

Chronic Leukemia

Treatment

VIII.-Hodgkin's Disease

History

Pathology

Disorders of the Reticulo-endothelial System

Symptoms

Treatment

IX.-Splenic Anemia (Banti's Disease)

History

Clinical Features

Differential Diagnosis

Pathogenesis

Treatment

X.-Hemolytic Jaundice

History

Congenital and Acquired Types

Symptoms

Pathogenesis

Treatment

XI.-Gaucher's Disease, Von Jaksch's Disease, Polycy

XII.-Differential Diagnosis

XIII.-On the Liver in Some of Its Relations to the Spleen

Multiple Pathological Classifications of Cirrhosis a Source of Confusion

Further Consideration of Minute Anatomy and Physiology of Liver

Method of Production of Cirrhosis

Circulatory and Infective Causes

Relationship of Spleen

Conception of Liver Acinus as Divided into Solid and Tubular Portions with Different Functions

Portal and Biliary Cirrhosis as Variants of a Single Type

Surgical Treatment and Its Aims

XIV.-Conclusion

Splenic Diseases not Isolated Entities but Local Manifestations of Systemic Disorder

Search to be Made for Site of Lesion and Type of Infective Agent at Work