The Role of 5-HT Systems on Memory and Dysfunctional Memory

The Role of 5-HT Systems on Memory and Dysfunctional Memory

Emergent Targets for Memory Formation and Memory Alterations

1st Edition - March 11, 2014

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  • Author: Alfredo Meneses
  • eBook ISBN: 9780128010839

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Description

Drugs acting through 5-HT (5-hydroxytryptamine, or serotonin) systems modulate memory and its alterations, but the mechanisms by which they do so are poorly understood. Agonists and antagonists for 5-HT receptors, as well as serotonin uptake inhibitors, present promnesic (memory-promoting) and/or anti-amnesic effects under different conditions, and 5-HT receptors are also associated with neural changes. The Role of 5-HT Systems on Memory and Dysfunctional Memory: Emergent Targets for Memory Formation and Memory Alterations reviews and summarizes the most recent research related to 5-HT drugs and the mechanisms by which they effect alterations in memory. This latest evidence is reviewed in the context of memory deficits related to brain disorders, such as post-traumatic stress disorder, schizophrenia, post-stroke cognitive dysfunctions, Parkinson’s disease, and infection-induced memory impairments. Written by an expert in the field of memory, The Role of 5-HT Systems on Memory and Dysfunctional Memory provides an introduction to the latest research on 5-HT receptors and their contributions to the physiological and pharmacological basis of memory.

Key Features

  • Examines and summarizes the recent advances in drugs that act through the 5-HT systems
  • Reviews findings in the context of brain disorders that involve memory deficits
  • Covers emergent targets for memory formation and memory alterations

Readership

Academics and students studying memory, neuroscience, pharmacology

Table of Contents

    • Dedication
    • Acknowledgments
    • Chapter 1. Introduction
    • Chapter 2. 5-HT Systems and Neurobiological Markers Related to Memory Systems
    • Chapter 3. 5-HT Pathways, Receptors and Transporter: Memory Functions and Dysfunctions
      • 3.1 Protocols of Training/Testing, Memory Tasks, and Drugs
      • 3.2 Evidence Relating 5-HT Receptors and SERT to Memory
    • Chapter 4. 5-HT1A Receptor
    • Chapter 5. 5-HT1B Receptor
    • Chapter 6. 5-HT1E/1F Receptor
    • Chapter 7. 5-HT2A/2B/2C Receptor
    • Chapter 8. 5-HT3 Receptor
    • Chapter 9. 5-HT4 Receptor
    • Chapter 10. 5-HT5 Receptor
    • Chapter 11. 5-HT6 Receptor
      • 11.1 Neural Markers and Memory Tasks
    • Chapter 12. 5-HT7 Receptor
      • 12.1 SERT
    • Conclusions
    • References

Product details

  • No. of pages: 92
  • Language: English
  • Copyright: © Academic Press 2014
  • Published: March 11, 2014
  • Imprint: Academic Press
  • eBook ISBN: 9780128010839

About the Author

Alfredo Meneses

Affiliations and Expertise

Department of Pharmacobiology, CINVESTAV (Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional), Mexico

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