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The Renal System
Systems of the Body Series
- 3rd Edition - June 9, 2022
- Authors: Vincent Lee, Amanda Mather
- Editor: Stephen H. Hughes
- Language: English
- Paperback ISBN:9 7 8 - 0 - 7 0 2 0 - 8 2 9 2 - 4
- eBook ISBN:9 7 8 - 0 - 7 0 2 0 - 8 2 9 3 - 1
The Systems of the Body series has established itself as a highly valuable resource for medical and other health science students following today’s systems-based courses. Now thoro… Read more
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Request a sales quoteThe Systems of the Body series has established itself as a highly valuable resource for medical and other health science students following today’s systems-based courses. Now thoroughly revised and updated in this third edition, each volume presents the core knowledge of basic science and clinical conditions that medical students need, providing a concise, fully integrated view of each major body system that can be hard to find in more traditionally arranged textbooks or other resources. Multiple case studies help relate key principles to current practice, with links to clinical skills, clinical investigation and therapeutics made clear throughout.
Each (print) volume also now comes with access to the complete, enhanced eBook version, offering easy anytime, anywhere access - as well as self-assessment material to check your understanding and aid exam preparation.
The Renal System
provides highly accessible coverage of the core basic science principles in the context of clinical case histories, giving the reader a fully integrated understanding of the system and its major diseases.
Introduction to the Renal System
Body Fluids, Nephron Function and Diuretics
Water Balance and Regulation of Osmolality
Acid–Base Balance and Regulation of pH
Glomerular Filtration and Acute Kidney Injury
Proteinuria and the Nephrotic Syndrome
Glomerulonephritis and the Acute Nephritic Syndrome
Diabetic Nephropathy and Chronic Kidney Disease
Kidney Failure and Replacement of Renal Function
Hypertension and the Kidney
Pregnancy and the Kidney
Urinary Tract Obstruction and Stones
Renal Masses, Cysts and Urinary Tract Tumours
Drugs and the Kidney
Systems of the Body
Series:
The Renal System
The Musculoskeletal System
The Nervous System
The Digestive System
The Endocrine System
The Respiratory System
The Cardiovascular System
- Cover image
- Title page
- Table of Contents
- Copyright
- Series Editor Foreword
- Preface
- Acknowledgements
- 1. Introduction to the Renal System
- Introduction
- Normal anatomy of the urinary tract
- Structure of the kidney
- Innervation of the urinary tract
- Embryology of the kidney and urinary tract
- Infection of the urinary tract
- Aetiology and pathogenesis of urinary tract infection
- Investigation of urinary tract infection
- Imaging of the urinary tract
- Vesicoureteric reflux
- Overview: treatment of urinary tract infections
- History and examination of the renal system
- Summary
- 2. Body fluids, nephron function, and diuretics
- Introduction
- Body fluid and electrolyte distribution
- Functional anatomy of the nephron
- Tubular modification of ultrafiltrate
- Sodium transport
- Regulation of sodium transport
- Potassium transport
- Pharmacology of diuretic agents
- Principles of fluid and electrolyte replacement therapy
- Summary
- 3. Water Balance And Regulation Of Osmolality
- Introduction
- Causes and assessment of polyuria
- Renal mechanisms for urine concentration
- Feedback control of plasma osmolality
- Failure to concentrate the urine
- Failure to dilute the urine
- Summary
- 4. Acid–Base Balance and Regulation of pH
- Introduction
- Role of the kidney in H+ balance
- Disturbances of acid–base balancedosis
- Disturbances of acid–base balance: alkalosis
- Summary of findings in principal acid–base disturbances
- Summary
- 5. Glomerular Filtration and Acute Kidney Injury
- Introduction
- Renal blood flow
- Glomerular filtration
- Autoregulation of renal blood flow and GFR
- Renal excretion and the clearance formula
- Measuring the GFR
- Pathophysiology of oliguria
- Causes of acute kidney injury
- Acute tubular necrosis
- Overview: assessment and management of a patient with AKI
- Biochemical changes in AKI
- Complications of AKI
- Management of AKI
- Summary
- Chapter 6. Proteinuria and the Nephrotic Syndrome
- Introduction
- Pathophysiology of oedema formation
- Glomerular anatomy and the filtration barrier
- Normal and abnormal proteinuria
- Nephrotic syndrome
- Natural history and response to treatment
- Summary
- 7. Glomerulonephritis and the Acute Nephritic Syndrome
- Introduction
- Urinary sediment examination
- Presentation and consequences of glomerular disease
- Investigation of glomerulonephritis
- Differential diagnosis of acute glomerulonephritis
- Pathogenesis of acute glomerulonephritis
- Outcome of glomerulonephritis
- Clinicopathological correlations in glomerulonephritis
- Summary
- 8. Diabetic Nephropathy and Chronic Kidney Disease
- Introduction
- Presentation of CKD
- Stages of CKD
- Causes of CKD
- Pathologic conditions of diabetic nephropathy and CKD
- Anaemia
- Cardiovascular disease
- Principles of treatment
- Management of consequences of CKD
- Summary
- 9. Kidney Failure and Replacement of Renal Function
- Introduction
- Replacement of kidney function
- Principles and modes of dialysis
- Supportive therapy for advanced CKD
- Summary
- Chapter 10. Hypertension and the kidney
- Introduction
- Determinants of normal blood pressure and role of the kidney
- Pathogenesis of essential hypertension
- The pathologic conditions of hypertension
- Principles in the management of hypertension
- Secondary hypertension
- Summary
- Chapter 11. Pregnancy and the Kidney
- Introduction
- Structural changes in the urinary tract during pregnancy
- Urinary tract infection in pregnancy
- Renal physiology changes in pregnancy
- Blood pressure and pregnancy
- Hypertension in pregnancy
- Management of hypertension in pregnancy
- Follow-up of patients with hypertension in pregnancy
- Pregnancy in patients with pre-existing kidney disease
- Summary
- 12. Urinary tract obstruction and stones
- Introduction
- Differential diagnosis of loin pain and haematuria
- Imaging of the urinary tract
- Pathophysiology of urinary tract obstruction
- Renal calculi
- Principles of treatment
- Summary
- 13. Renal masses, cysts, and urinary tract tumours
- Introduction
- Differential diagnosis of a renal mass
- Simple cysts
- Renal cell carcinoma
- Polycystic kidney disease
- Differential diagnosis of microscopic haematuria
- Urothelial cell carcinoma of the bladder
- Other urinary tract tumours
- Summary
- 14. Drugs and the Kidney
- Introduction
- Part A
- Altered pharmacokinetics in renal disease
- Drug dosing in kidney impairment
- Part B
- Mechanisms of nephrotoxicity
- Important causes of nephrotoxicity
- Summary
- Appendix: normal ranges
- Index
- No. of pages: 180
- Language: English
- Edition: 3
- Published: June 9, 2022
- Imprint: Elsevier
- Paperback ISBN: 9780702082924
- eBook ISBN: 9780702082931
VL
Vincent Lee
Affiliations and expertise
Renal Physician, Westmead & Blacktown Hospitals, Norwest Private Hospital
Clinical Associate Professor and Academic Lead (Medicine), Sydney Medical School – Westmead, University of SydneyAM
Amanda Mather
Affiliations and expertise
Renal Physician,
Royal North Shore Hospital
Sydney, Australia