The Pituitary

3rd Edition

Editors: Shlomo Melmed
Hardcover ISBN: 9780123809261
eBook ISBN: 9780123809278
Imprint: Academic Press
Published Date: 3rd December 2010
Page Count: 744
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Description

The pituitary, albeit a small gland, is known as the "master gland" of the endocrine system and contributes to a wide spectrum of disorders, diseases, and syndromes. Since the publication of the second edition of The Pituitary, in 2002, there have been major advances in the molecular biology research of pituitary hormone production and action and there is now a better understanding of the pathogenesis of pituitary tumors and clinical syndromes resulting in perturbation of pituitary function. There have also been major advances in the clinical management of pituitary disorders. Medical researchers and practitioners now better understand the morbidity and mortality associated with pituitary hormone hyposecretion and hypersecretion. Newly developed drugs, and improved methods of delivering established drugs, are allowing better medical management of acromegaly and prolactinoma. These developments have improved the worldwide consensus around the definition of a "cure" for pituitary disease, especially hormone hypersecretion, and hence will improve the success or lack of success of various forms of therapy. It is therefore time for a new edition of The Pituitary.

The third edition will continue to be divided into sections that summarize normal hypothalamic-pituitary development and function, hypothalamic-pituitary failure, and pituitary tumors; additional sections will describe pituitary disease in systemic disorders and diagnostic procedures, including imaging, assessment of the eyes, and biochemical testing.

The first chapter will be completely new – placing a much greater emphasis on physiology and pathogenesis. Two new chapters will be added on the Radiation and Non-surgical Management of the Pituitary and Other Pituitary Lesions. Other chapters will be completely updated and many new author teams will be invited. The second edition published in 2002 and there have been incredible changes in both the research and clinical aspects

Key Features

  • Presents a comprehensive, translational source of information about the pituitary in one reference work
  • Pituitary experts (from all areas of research and practice) take readers from the bench research (cellular and molecular mechanism), through genomic and proteomic analysis, all the way to clinical analysis (histopathology and imaging) and new therapeutic approaches
  • Clear presentation by endocrine researchers of the cellular and molecular mechanisms underlying pituitary hormones and growth factors as well as new techniques used in detecting lesions (within the organ) and other systemic disorders
  • Clear presentation by endocrinologists and neuroendocrine surgeons of how imaging, assessment of the eyes, and biochemical testing can lead to new therapeutic approaches

Readership

Endocrinologists and researchers of endocrine diseases across biomedical disciplines, as well as those working with endocrinologists such as neurosurgeons and OB/GYNs

Table of Contents

Section 1 Hypothalamic-Pituitary Function

1. Functional Anatomy of the Hypothalamic Pituitary Axis

Shlomo Melmed, Cedars-Sinai Medical Center, Los Angeles

2. Adrenocorticotropin

Mark A. Herman, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas

Joseph A. Majzoub, Children’s Hospital, Harvard Medical School, Division of Endocrinology, Boston

3. Growth Hormone

Vivien S. Herman-Bonert, UCLA School of Medicine, Division of Endocrinology, Los Angeles

Shlomo Melmed, Cedars-Sinai Medical Center, Los Angeles

4. Prolactin

Mark E. Molitch, Northwestern University Medical School, Center for Endocrinology, Metabolism, and Molecular Medicine

5. Thyroid-stimulating Hormone

Chester E. Ridgway, University of Colorado Health Sciences Center, Division of Endocrinology

6. Follicle-stimulating Hormone and Leutinizing Hormone

Ronald S. Swerdloff, Harbor/UCLA Medical Center, UCLA School of Medicine, Division of Endocrinology

Shalender Bhasin, Drew University School of Medicine, Division of Endocrinology, Metabolism, and Molecular Medicine

7. The Posterior Pituitary

Daniel G. Bichet, University of Montreal, Department of Medicine, Montreal

Section 2 Hypothalamic-Pituitary Dysfunction

8. The Hypothalamus

Glenn D. Braunstein, Cedars-Sinai Medical Center/UCLA School of Medicine, Los Angeles

9. Anterior Pituitary Failure

Charles F. Abboud, Mayo Clinic, Mayo Medical School, Rochester

Sect. 3 Pituitary Tumors

10. Pituitary Surgery

Rudolf Fahlbusch, Professor of Neurosurgery, University of Erlangen-Nurnberg, Germany

11. Radiation and Non-surgical Management of the Pituitary

Laurence Katznelson, Stanford University School of Med

Details

No. of pages:
744
Language:
English
Copyright:
© Academic Press 2011
Published:
Imprint:
Academic Press
eBook ISBN:
9780123809278
Hardcover ISBN:
9780123809261

About the Editor

Shlomo Melmed

Dr. Melmed co-edits Endocrinology: Basic and Clinical Principles, is the Neuroendocrine Section Editor for DeGroot and Jameson's Textbook of Endocrinology, and Williams Textbook of Endocrinology; and is pituitary section author for Harrison's Textbook of Medicine. In addition to being the Editor-in-Chief of Pituitary, he is on the editorial board of Journal of Clinical Investigation and past Editor-in-Chief of Endocrinology.

Affiliations and Expertise

Professor of Medicine, Senior Vice President and Dean of the Medical Faculty, Cedars Sinai Health System, Los Angeles, CA, USA

Reviews

"…the book is not only a must for scientists and clinicians usually involved in the management of neuroendocrine dysfunctions but also a great opportunity for other specialists (internists, pediatricians, gynecologists, neurosurgeons) as well as for medical students to familiarize at best with the pituitary and its disorders. In all, this book is a traditional masterpiece dedicated to the ‘‘master gland’’ by one of the most important opinion leaders in the field."--Endocrine 2012

"[T]he book provides the reader a unique opportunity to understand in depth the mechanisms subserving both normal and disordered pituitary hormone secretion and action. Thus, the book is not only a must for scientists and clinicians usually involved in the management of neuroendocrine dysfunctions but also a great opportunity for other specialists (internists, pediatricians, gynecologists, neurosurgeons) as well as for medical students to familiarize at best with the pituitary and its disorders. In all, this book is a traditional masterpiece dedicated to the ‘‘master gland’’ by one of the most important opinion leaders in the field." --Endocrine

SECOND EDITION:
"This excellent second edition is an update of the highly successful first edition of The Pituitary, published in 1995…All the chapters were written by leading experts in the field; a particularly welcome addition is a chapter dedicated to pituitary surgery, by Fahlbusch and colleagues. All the chapters have been successfully updated, and all are comprehensively referenced. The new edition describes recent developments in medical therapies for acromegaly (and thyrotropin-producing adenomas), especially the role of long-acting forms of somatostatin analogues and new growth hormone-receptor antagonists, as well as newer and more effective dopamine agonists for patients with prolactinoma. Inevitably, availability and licensing are subject to worldwide variations and differences in