The Ovary

The Ovary

2nd Edition - December 18, 2003

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  • Editors: Peter Leung, Peter Leung, Eli Adashi
  • eBook ISBN: 9780080542584

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This second edition of The Ovary incorporates the dramatic research developments regarding the ovarian life cycle within the past decade. It looks at ovarian function from a detailed molecular and cellular level. The updated chapters, along with the new material, represent an unparalleled compilation of chapters relevant to contemporary ovarian physiology. The book is divided into 8 sections: The Ovarian Follicular Apparatus: Operational Characteristics; Oocyte Maturation and Ovulation; The Corpus Luteum; Putative Intraovarian Regulators; Cyclic Ovarian Cell Death; Novel Experimental Models; Human Ovarian Pathophysiology: Select Aspects; and Human Ovarian Surface Epithelium and Neoplasia.

Key Features

* Addresses all phases of the ovarian life cycle
* New information includes the latest developments
in ovarian surface epithelium
* Contains 38 in-depth chapters


Reproductive endocrinologists, physiologists, cell and molecular biologists, fertility/infertility specialists, as well as obstetriticans and gynocologists.

Table of Contents

  • Neural and Neurotrophic Control of Ovarian Development
    Dynamics of Human Follicular Growth: Morphologic, Dynamic and Functional Aspects
    Dynamics of Primate Follicular Growth: A Physiologic Perspective
    Functional Consequences of Mutations and Polymorphisms in Gonadotropin and Gonadotropin Receptor Genes
    The Regulation of Gonadotropin Receptor in the Ovary
    Prostaglandin Biosynthesis and Action in the Ovary
    Actions of Insulin IGF-I on sterol-metabolizing Gene Expression in Ovarian Cells
    Intracellular Cholesterol Dynamics in Steroidogenic Cells
    Regulation of Mammalian Oocyte Maturation
    Oocyte-Granulosa Cell Interactions
    Ovulation: An Inflammatory Cascade of Gene Expression
    The Function and Regulation of Cell Populations Composing
    The Corpus Luteum of the Ovarian Cycle
    The Corpus Luteum of Pregnancy
    Potential Role of Cytokines in Ovarian Physiology: The Case for Interleukin-1
    Activin, Inhibin and Follistatin in Ovarian Physiology
    GnRH as an Autocrine Regulator in the Human Ovary
    Ovarian Angiogenesis
    Apoptosis in Ovarian Development, Function and Failure
    Reactive Oxygen Species and Ovarian Function
    Follicle Selection in Mammalian Ovaries: Regulatory Mechanisms of Granulosa Cell Apoptosis during Follicular Atresia
    Generation and Application of Ovarian Steroidogenic Cell Lines
    The Application of Gene Ablation and Related Technologies to the Study of Ovarian Function
    Bioinformatic Analysis of Ovarian Genes Using an Ovary-Specific Database
    Human Ovarian Pathophysiology: Select Aspects
    Gonadotropin Ovulation Induction
    The Role of GnRH Antagonists in Supporting Ovarian Hyperstimulation
    The Ovarian Factor in Assisted Reproductive Technology
    Ovarian Function in Assisted Reproduction
    Polycystic Ovary Syndrome
    The Role of the Ovary in the Genesis of Hyperandrogenism
    Luteal Dysfunction
    Germ Cell Failure and Ovarian Resistance: Human Genes and Disorders
    Ovarian Function and Survival of Patients with Cervical Carcinoma Treated with Radical Hysterectomy and Ovarian Transposition
    Role of Mitochondria in the Aging Ovary
    Development & Differentiation of Ovarian Surface Epithelium: Cues for the Basis of its Malignant Potential
    Molecular Mechanisms of Ovarian Neoplastic Progression
    Ovarian Carcinogenesis
    The Role of X-Linked Inhibitor of Apoptosis Protein in Chemoresistant Ovarian Cancer

Product details

  • No. of pages: 664
  • Language: English
  • Copyright: © Academic Press 2003
  • Published: December 18, 2003
  • Imprint: Academic Press
  • eBook ISBN: 9780080542584

About the Editors

Peter Leung

Affiliations and Expertise

University of British Columbia, Vancouver, British Columbia, Canada

Peter Leung

Peter Leung
Dr. Leung is a Professor at the University of British Columbia’s Department of Obstetrics & Gynecology and former Associate Dean in the Faculty of Medicine at UBC. Dr. Leung received his PhD from Western University. After post-doctoral training at the University of California at Los Angeles and the Laval University, he joined the University of British Columbia in 1982 as a faculty member. Dr. Leung has received a number of prestigious awards, including a Scholar Award and a Scientist Award from the Medical Research Council of Canada, a Distinguished Scholar Award from the Michael Smith Foundation for Health Research and a Senior Scientist Award from the BC Children Hospital Research Institute. Dr. Leung has served on many national and international organizations, including as President of the Canadian Fertility and Andrology Society, Director of the Society for the Study of Reproduction, Director of the Ovarian Workshops in the USA, temporary advisor to the World Health Organization, Fellow of the Canadian Academy for Health Sciences, and Fellow of the Royal Society of Canada. Dr. Leung’s research focuses on hormonal determinants of women’s reproductive health. His publication record to date includes 400 papers, 350 abstracts, 22 book chapters and 7 monographs. Since his appointment at UBC, Dr. Leung has served as the research supervisor for more than 100 graduate students, postdoctoral fellows and visiting scientists.

Affiliations and Expertise

Professor, Department of Obstetrics and Gynecology, University of British Columbia, Canada

Eli Adashi

Affiliations and Expertise

University of Utah, Salt Lake City, Utah, U.S.A.

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