This second edition of The Ovary incorporates the dramatic research developments regarding the ovarian life cycle within the past decade. It looks at ovarian function from a detailed molecular and cellular level. The updated chapters, along with the new material, represent an unparalleled compilation of chapters relevant to contemporary ovarian physiology. The book is divided into 8 sections: The Ovarian Follicular Apparatus: Operational Characteristics; Oocyte Maturation and Ovulation; The Corpus Luteum; Putative Intraovarian Regulators; Cyclic Ovarian Cell Death; Novel Experimental Models; Human Ovarian Pathophysiology: Select Aspects; and Human Ovarian Surface Epithelium and Neoplasia.

Key Features

* Addresses all phases of the ovarian life cycle * New information includes the latest developments in ovarian surface epithelium * Contains 38 in-depth chapters


Reproductive endocrinologists, physiologists, cell and molecular biologists, fertility/infertility specialists, as well as obstetriticans and gynocologists.

Table of Contents

Neural and Neurotrophic Control of Ovarian Development Dynamics of Human Follicular Growth: Morphologic, Dynamic and Functional Aspects Dynamics of Primate Follicular Growth: A Physiologic Perspective Functional Consequences of Mutations and Polymorphisms in Gonadotropin and Gonadotropin Receptor Genes The Regulation of Gonadotropin Receptor in the Ovary Prostaglandin Biosynthesis and Action in the Ovary Actions of Insulin IGF-I on sterol-metabolizing Gene Expression in Ovarian Cells Intracellular Cholesterol Dynamics in Steroidogenic Cells Regulation of Mammalian Oocyte Maturation Oocyte-Granulosa Cell Interactions Ovulation: An Inflammatory Cascade of Gene Expression The Function and Regulation of Cell Populations Composing The Corpus Luteum of the Ovarian Cycle Luteinization The Corpus Luteum of Pregnancy Potential Role of Cytokines in Ovarian Physiology: The Case for Interleukin-1 Activin, Inhibin and Follistatin in Ovarian Physiology GnRH as an Autocrine Regulator in the Human Ovary Ovarian Angiogenesis Apoptosis in Ovarian Development, Function and Failure Reactive Oxygen Species and Ovarian Function Follicle Selection in Mammalian Ovaries: Regulatory Mechanisms of Granulosa Cell Apoptosis during Follicular Atresia Generation and Application of Ovarian Steroidogenic Cell Lines The Application of Gene Ablation and Related Technologies to the Study of Ovarian Function Bioinformatic Analysis of Ovarian Genes Using an Ovary-Specific Database Human Ovarian Pathophysiology: Select Aspects Gonadotropin Ovulation Induction The Role of GnRH Antagonists in Supporting Ovarian Hyperstimulation The Ovarian Factor in


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© 2003
Academic Press
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About the authors

Peter Leung

Affiliations and Expertise

University of British Columbia, Vancouver, British Columbia, Canada

Eli Adashi

Affiliations and Expertise

University of Utah, Salt Lake City, Utah, U.S.A.


"The chapters are well written...The Ovary should be of great value to established scholars in the field because it conveniently reviews the developments of the past decade and will quickly bring them up to date. This handsome volume can be highly recommended. Each chapter is amply referenced, making this book a great resource for anyone with a detailed interest in the ovary." -TRENDS IN ENDOCRINOLOGY AND METABOLISM, SEPTEMBER 2004 "...a comprehensive reference and value for the money...more for those who are curious to enquire into the scientific basis of clinical medicine." --David T. Baird, MB BChr, DSc, Professor Emeritus, University Department of Obstetrics and Gynaecology and Director ofo Contraceptive Development Network, Edinburgh, UK for Journal of Family Planning and Reproductive Health Care, Vol. 31, No. 1 June 20052004