The Nervous System

The Nervous System

Central Nervous System Drugs

1st Edition - January 1, 1965

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  • Editors: Walter S. Root, Frederick G. Hofmann
  • eBook ISBN: 9781483275833

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Physiological Pharmacology: A Comprehensive Treatise, Volume II: The Nervous System — Part B, Central Nervous System Drugs focuses on the effects of drugs on the functions of the central nervous system. The selection first offers information on depressant and anticonvulsant drugs. Topics include neurophysiological substrate of drug action; pharmacological properties of selected muscle relaxants; anticonvulsants and their mechanisms; and definitive seizure mechanisms. The book also takes a look at antitussive drugs and psychic energizers and antidepressant drugs. The publication examines emetic and antiemetic drugs, as well as neural mechanisms of emesis, emetic syndromes and agents, and antiemetic agents. The text also reviews the effects of drugs on the eyes and synoptic transmission in the central nervous system. Discussions focus on the effect of drugs used in the therapy of ocular disease; undesirable eye effects of ophthalmic and other drugs; and chemical transmitters in the central nervous system. The selection is a dependable reference for readers interested in the effects of drugs on the central nervous system.

Table of Contents

  • Contributors

    Foreword to Volume I


    Contents Of Volume III

    I. Depressant Drugs (Continued)

    G. Relaxants of Skeletal Muscle

    I. Introduction

    II. Neurophysiological Substrate of Drug Action

    III. Pharmacological Properties of Selected Muscle Relaxants

    IV. Comments on Therapeutic Usefulness


    H. Anticonvulsant Drugs

    I. Introduction

    II. Clinical and Experimental Seizures

    III. Anticonvulsants and Their Mechanisms

    IV. Definitive Seizure Mechanisms


    I. Antitussive Drugs

    I. General Considerations

    II. The Pathophysiology of Cough

    III. Pharmacodynamic Characteristics of Antitussives

    IV. Concluding Remarks

    Appendix: Method of Searching for Agents Having Selective Effects on Active Expiratory Processes


    II. Psychic Energizers and Antîdepressant Drugs

    I. Introduction

    II. Monoamine Oxidase Inhibitors

    III. Iminodibenzyl Derivatives

    IV. The Physiological and Pharmacological Basis of the Clinical Treatment of Depressions


    III. Emetic and Antiemetic Drugs

    I. Introduction

    II. Neural Mechanism of Emesis

    III. Emetic Agents

    IV. Emetic Syndromes

    V. Antiemetic Agents


    IV. The Effects of Drugs upon the Eye

    I. Unique Ophthalmic Factors

    II. The Effect of Drugs Used in the Therapy of Ocular Disease

    III. Undesirable Eye Effects of Ophthalmic and Other Drugs

    IV. Undesirable Systemic Effects of Ophthalmic Drugs


    V. Synoptic Transmission in the Central Nervous System

    I. Introduction

    II. The Structure of Central Synapses

    III. The Electrophysiology of Synapses

    IV. Chemical Transmitters in the Central Nervous System

    V. Transmitter Release


    Author Index

    Subject Index

Product details

  • No. of pages: 502
  • Language: English
  • Copyright: © Academic Press 1965
  • Published: January 1, 1965
  • Imprint: Academic Press
  • eBook ISBN: 9781483275833

About the Editors

Walter S. Root

Frederick G. Hofmann

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