The Nervous System - 1st Edition - ISBN: 9781483227603, 9781483272948

The Nervous System

1st Edition

Autonomic Nervous System Drugs

Editors: Walter S. Root Frederick G. Hofmann
eBook ISBN: 9781483272948
Imprint: Academic Press
Published Date: 1st January 1967
Page Count: 534
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Physiological Pharmacology: A Comprehensive Treatise, Volume III: The Nervous System — Part C: Autonomic Nervous System Drugs focuses on the effects of drugs on the nervous system, including cardiovascular effects and metabolism.
The selection first offers information on the cardiovascular effects of choline esters and the effects of choline esters on smooth muscles and secretions. Topics include actions of acetylcholine, physiological role of choline esters, and actions of cholinergic drugs on smooth muscles and secretions. The book also takes a look at the pharmacologic, toxicologic, and therapeutic properties of anticholinesterase agents, including the chemistry and metabolism of anticholinesterase substances and mechanisms of action of anticholinesterase agents and role of cholinesterases.
The publication examines muscarinic blocking drugs and ganglion-blocking drugs. Discussions focus on actions on the secretory glands and cardiovascular system; distribution, metabolism, and excretion of atropine; substances that block ganglionic transmission; and cardiovascular effects. The text also elaborates on neuromuscular blocking drugs.
The selection is a dependable reference for readers interested in the effects of drugs on the nervous system.

Table of Contents

Contributors to Volume III Foreword Contents of Previous Volumes I. Cholinergic Drugs A. Cardiovascular Effects of Choline Esters I. Introduction II. Actions of Acetylcholine III. Esters Related to Acetylcholine IV. On the Physiological Role of Choline Esters References B. Effects of Choline Esters on Smooth Muscle and Secretions I. Introduction II. The Actions of Cholinergic Drugs on Smooth Muscle III. The Action of Cholinergic Drugs on Secretions References C. Pharmacologic, Toxicologic, and Therapeutic Properties of Anticholinesterase Agents I. Introduction II. Activities of Cholinesterases, Their Inhibition and Reactivation III. Distribution of Cholinesterases IV. Distribution of Choline Acetylase and of Acetylcholine V. Chemistry and Metabolism of Anticholinesterase Substances VI. Special Pharmacology of Anticholinesterases VII. Therapeutics VIII. Toxicity and its Treatment IX. Mechanisms of Action of Anticholinesterase Agents and Role of Cholinesterases References II. Cholinergic Blocking Drugs A. Muscarinic Blocking Drugs I. Introduction II. Sources III. History IV. Chemistry V. Mechanism of Action VI. Actions on the Secretory Glands VII. Actions on Smooth Muscle VIII. Actions on the Cardiovascular System IX. Actions on the Central Nervous System X. Actions on Other Nervous Tissues XI. Distribution, Metabolism, and Excretion of Atropine References B. Ganglion-Blocking Drugs I. Introduction II. Substances Which Block Ganglionic Transmission III. Effects of Ganglion Blockade IV. Mode of Action V. Cardiovascular Effects VI. Selec


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© Academic Press 1967
Academic Press
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About the Editor

Walter S. Root

Frederick G. Hofmann

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