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The Nervous System
Systems of the Body Series
- 3rd Edition - June 11, 2022
- Authors: Adina T. Michael-Titus, Peter Shortland
- Editor: Stephen H. Hughes
- Language: English
- Paperback ISBN:9 7 8 - 0 - 7 0 2 0 - 8 3 4 0 - 2
- eBook ISBN:9 7 8 - 0 - 7 0 2 0 - 8 3 4 1 - 9
The Systems of the Body series has established itself as a highly valuable resource for medical and other health science students following today’s systems-based courses. Now thoro… Read more
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Request a sales quoteThe Systems of the Body series has established itself as a highly valuable resource for medical and other health science students following today’s systems-based courses. Now thoroughly revised and updated in this third edition, each volume presents the core knowledge of basic science and clinical conditions that medical students need, providing a concise, fully integrated view of each major body system that can be hard to find in more traditionally arranged textbooks or other resources. Multiple case studies help relate key principles to current practice, with links to clinical skills, clinical investigation and therapeutics made clear throughout.
Each (print) volume also now comes with access to the complete, enhanced eBook version, offering easy anytime, anywhere access - as well as self-assessment material to check your understanding and aid exam preparation.
The Nervous System
provides highly accessible coverage of the core basic science principles in the context of clinical case histories, giving the reader a fully integrated understanding of the system and its major diseases.
Organization of the Nervous System
Elements of Cellular and Molecular Neuroscience
Clinical Assessment
The Spinal Cord
Pain and Analgesia
Cranial Nerves and the Brainstem
The Visual System
Hearing and Balance: The Auditory and Vestibular Systems
Motor Systems I: Descending Pathways and Cerebellum
Motor Systems II: The Basal Ganglia
Stroke and Head Injury
Infection in the Central Nervous System
Epilepsy
Dementia
Schizophrenia and Neurodevelopmental Disorders
Depression and Anxiety
Addiction
Systems of the Body
Series:
The Renal System
The Musculoskeletal System
The Nervous System
The Digestive System
The Endocrine System
The Respiratory System
The Cardiovascular System
- Cover image
- Title page
- Table of Contents
- Copyright
- Acknowledgements
- Series Editor Foreword
- Preface
- 1. Organization of the Nervous System
- Introduction
- Overview of brain anatomy
- Internal anatomy of the brain
- Forebrain
- Hemisphere specialization
- Limbic system
- Orbitofrontal cortex
- Basal ganglia
- Diencephalon
- Thalamus
- Hypothalamus
- Peripheral nervous system
- Putting it all together: from anatomy to behaviour
- 2. Elements of Cellular And Molecular Neuroscience
- Introduction
- Neurons
- Glial cells
- Neuron excitability
- Postsynaptic events and postsynaptic receptors
- Neurotransmitter synthesis
- Neurotransmitter inactivation
- Summation and neuronal integration
- 3. Clinical Assessment
- Introduction
- Component parts of the clinical examination
- Other investigations
- General comments
- 4. The Spinal Cord
- Introduction
- Gross anatomy of the spinal cord and vertebral column
- Functional organization of the spinal cord
- Spinal cord cell types
- Receptive fields
- Somatosensory pathways
- Blood supply to the spinal cord
- Damage to the spinal cord
- Comments on the case history
- Self-assessment case study
- 5. Pain and Analgesia
- Introduction
- Nociceptors
- Pain pathways
- Visceral and muscular pain pathways
- How does the central nervous system interpret a stimulus as painful?
- Physiology of pain modulation
- Counter-stimulation analgesia
- Supraspinal (descending) analgesia
- Acupuncture analgesia
- Arousal analgesia
- Psychology of pain
- Measuring pain
- Pain mechanisms after tissue damage: peripheral and central sensitization
- Neuropathic pain mechanisms
- Glial cells and neuropathic pain
- Pharmacology of pain
- Opioid receptors and ligands
- Opioid analgesic drugs
- Opioid antagonists
- Pain sensitivity to opioids
- Non-opioid analgesics
- Other approaches to pain management
- Neuropathic pain
- Migraine
- Treatment of migraine attacks
- Preventive treatment of migraine
- Trigeminal neuralgia
- Pain in children and in the elderly
- General comments on pain management
- Self-assessment case study
- 6. Cranial Nerves and the Brainstem
- Introduction
- Anatomical organization of cranial nerves and their nuclei
- Internal organization of the brainstem
- Reticular formation
- Blood supply to the brainstem
- Brainstem reflexes
- Brainstem lesions
- Comments on the case history
- Self-assessment case study
- 7. The Visual System
- Introduction
- Structure of the eye
- Visual pathways
- Visual field defects
- Pupillary light reflexes
- Focusing of light on the retina
- Control of eye movements
- Structure and function of the retina
- Processing of visual information
- Summary
- Self-assessment case study
- 8. Hearing and Balance: The Auditory and Vestibular Systems
- Introduction
- Auditory system
- Vestibular system
- Comments on the case history
- 9. Motor Systems I: Descending Pathways and Cerebellum
- Introduction
- Skeletal muscle contraction
- Reflexes
- Descending pathways
- Clinical importance of reflexes
- The cerebellum
- Self-assessment case study
- 10. Motor Systems II: The Basal Ganglia
- Introduction
- Basal ganglia: structure and organization
- Parkinson’s disease
- Huntington’s disease
- Self-assessment case study
- 11. Stroke and Head Injury
- Introduction
- Physiological control of cerebral blood flow
- Blood supply to the brain
- Stroke
- Head injury
- Focal pathology in relation to vascular injury
- Treatment of head injury
- Comments on the case history
- Self-assessment case study
- 12. Infection in the Central Nervous System
- Introduction
- Types of infection of the central nervous system
- The meninges
- Cerebrospinal fluid production and circulation
- Meningitis
- Encephalitis
- Cerebral abscesses
- Brain infections in the immunocompromised patient
- Self-assessment case study
- 13. Epilepsy
- Introduction
- General description of epilepsy
- Epidemiology and causes of epilepsy
- Diagnostic investigations of epilepsy
- Examples of types of seizure
- Pharmacological treatment of epilepsy
- Other treatments for epilepsy
- Treatment of status epilepticus
- Social consequences of epilepsy
- Self-assessment case study
- 14. Dementia
- Introduction
- Causes and diagnosis of dementia
- Neurobiology of learning and memory
- Alzheimer’s disease
- Treatment of Alzheimer’s disease
- Other types of dementia
- General considerations in the management of Alzheimer’s disease and other types of dementia
- Self-assessment case study
- 15. Schizophrenia and Neurodevelopmental Disorders
- Introduction
- Schizophrenia: the clinical diagnosis
- Aetiology of schizophrenia
- Neurobiology of schizophrenia
- Treatment of schizophrenia
- Comments on the management of schizophrenia and the long-term prognosis
- Other psychoses and neurodevelopmental disorders
- Self-assessment case study
- 16. Depression and Anxiety
- Introduction
- Classification of mood disorders
- Clinical features of mood disorders
- Epidemiology of depressive and bipolar disorders and their natural evolution
- Genetics of mood disorders
- Neurobiology of depression
- Treatment of depression
- Bipolar disorder and its treatment
- General comments on mood disorders
- Need for new therapeutic targets
- Comments on case history
- Anxiety disorders
- Treatment of anxiety disorders
- Insomnia
- Self-assessment case study
- 17. Addiction
- Introduction
- Addiction and drug misuse: general comments
- Neurobiology of addiction
- Addiction and rehabilitation: general comments
- Index
- No. of pages: 344
- Language: English
- Edition: 3
- Published: June 11, 2022
- Imprint: Elsevier
- Paperback ISBN: 9780702083402
- eBook ISBN: 9780702083419
AM
Adina T. Michael-Titus
Affiliations and expertise
Senior Lecturer in Neuroscience and Pharmacology, St Bartholomew's and the Royal London School of Medicine and Dentistry, London, UKPS
Peter Shortland
Affiliations and expertise
Lecturer in Anatomy, Neuroscience Section, Queen Mary and Westfield College, London, UK