The Mouse Nervous System

The Mouse Nervous System

1st Edition - September 22, 2011

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  • Editors: Charles Watson, George Paxinos, Luis Puelles
  • eBook ISBN: 9780080919188
  • Hardcover ISBN: 9780123694973

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The Mouse Nervous System provides a comprehensive account of the central nervous system of the mouse. The book is aimed at molecular biologists who need a book that introduces them to the anatomy of the mouse brain and spinal cord, but also takes them into the relevant details of development and organization of the area they have chosen to study. The Mouse Nervous System offers a wealth of new information for experienced anatomists who work on mice. The book serves as a valuable resource for researchers and graduate students in neuroscience.

Key Features

  • Systematic consideration of the anatomy and connections of all regions of the brain and spinal cord by the authors of the most cited rodent brain atlases
  • A major section (12 chapters) on functional systems related to motor control, sensation, and behavioral and emotional states
  • A detailed analysis of gene expression during development of the forebrain by Luis Puelles, the leading researcher in this area
  • Full coverage of the role of gene expression during development and the new field of genetic neuroanatomy using site-specific recombinases
  • Examples of the use of mouse models in the study of neurological illness


Neuroscientists, neuropathologists, neurologists, graduate students in neuroscience, and medical students.

Table of Contents

  • Dedication

    List of Contributors



    Chapter 1. Molecular Regionalization of the Developing Neural Tube

    Chapter 2. Gene Targeting

    Chapter 3. Genetic Neuroanatomy

    Chapter 4. Neocortex

    Chapter 5. Hippocampus

    Chapter 6. Piriform Cortex and Amygdala

    Chapter 7. Subpallial Structures

    Chapter 8. Hypothalamus

    Chapter 9. Diencephalon

    Chapter 10. Midbrain

    Chapter 11. Cerebellum

    Chapter 12. Hindbrain

    Chapter 13. Spinal Cord

    Chapter 14. Vascular Supply

    Chapter 15. Magnetic Resonance Imaging of the Mouse Brain

    Chapter 16. Motor Nuclei of the Cranial Nerves

    Chapter 17. Visceral Motoneurons

    Chapter 18. Neurosecretory Nuclei of the Hypothalamus and Preoptic Area

    Chapter 19. Motor Cortex

    Chapter 20. Hypothalamic Goal-directed Behavior – Ingestive, Reproductive and Defensive

    Chapter 21. The Somatosensory System

    Chapter 22. Gustatory

    Chapter 23. Pain

    Chapter 24. Auditory System

    Chapter 25. Visual System

    Chapter 26. The Olfactory System

    Chapter 27. Vestibular System

    Chapter 28. The Basal Forebrain Cholinergic Projection System in Mice

    Chapter 29. An Introduction to the Neurobiology of Emotions and Social Behavior

    Chapter 30. Prefrontal Cortex

    Chapter 31. Overview of Mouse Models for Psychiatric and Neurologic Disorders

    Chapter 32. Mouse Models of Mental Illness and Neurological Disease

    Chapter 33. The Neuroanatomy of Addictive Processes


Product details

  • No. of pages: 814
  • Language: English
  • Copyright: © Academic Press 2011
  • Published: September 22, 2011
  • Imprint: Academic Press
  • eBook ISBN: 9780080919188
  • Hardcover ISBN: 9780123694973

About the Editors

Charles Watson

Charles Watson is a neuroscientist and public health physician. His qualifications included a medical degree (MBBS) and two research doctorates (MD and DSc). He is Professor Emeritus at Curtin University, and holds adjunct professorial research positions at the University of New South Wales, the University of Queensland, and the University of Western Australia. He has published over 100 refereed journal articles and 40 book chapters, and has co-authored over 25 books on brain and spinal cord anatomy. The Paxinos Watson rat brain atlas has been cited over 80,000 times. His current research is focused on the comparative anatomy of the hippocampus and the claustrum. He was awarded the degree of Doctor of Science by the University of Sydney in 2012 and received the Distinguished Achievement Award of the Australasian Society for Neuroscience in 2018.

Affiliations and Expertise

John Curtin Distinguished Professor of Health Science, Curtin University of Technology, Perth, Australia and Neuroscience Research Australia, NSW Sydney, Australia

George Paxinos

George Paxinos
Professor George Paxinos, AO (BA, MA, PhD, DSc) completed his BA at The University of California at Berkeley, his PhD at McGill University, and spent a postdoctoral year at Yale University. He is the author of almost 50 books on the structure of the brain of humans and experimental animals, including The Rat Brain in Stereotaxic Coordinates, now in its 7th Edition, which is ranked by Thomson ISI as one of the 50 most cited items in the Web of Science. Dr. Paxinos paved the way for future neuroscience research by being the first to produce a three-dimensional (stereotaxic) framework for placement of electrodes and injections in the brain of experimental animals, which is now used as an international standard. He was a member of the first International Consortium for Brain Mapping, a UCLA based consortium that received the top ranking and was funded by the NIMH led Human Brain Project. Dr. Paxinos has been honored with more than nine distinguished awards throughout his years of research, including: The Warner Brown Memorial Prize (University of California at Berkeley, 1968), The Walter Burfitt Prize (1992), The Award for Excellence in Publishing in Medical Science (Assoc Amer Publishers, 1999), The Ramaciotti Medal for Excellence in Biomedical Research (2001), The Alexander von Humbolt Foundation Prize (Germany 2004), and more.

Affiliations and Expertise

Neuroscience Research Australia and The University of New South Wales, Sydney, Australia

Luis Puelles

Dr. Puelles has held various positions teaching human anatomy and conducting research in neuroembryology and comparative neuroanatomy at the Universities of Granada, Sevilla, Badajoz, Cadiz and Murcia in Spain. Since 1983 he has been Full professor of Neuroanatomy at the University of Murcia. He is author of ~230 works, notably the first edition of Chick Brain in Stereotaxic Coordinates, and co-editor of Elsevier’s The Mouse Nervous System.

Affiliations and Expertise

Instituto de Neurociencias, UMH-CSIC, San Juan, Alicante, Spain

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