The Molecular Pathology of Neurodegenerative Disease - 1st Edition - ISBN: 9780128110690

The Molecular Pathology of Neurodegenerative Disease

1st Edition

Authors: Patrick A. Lewis Jennifer E. Spillane
Paperback ISBN: 9780128110690
Imprint: Academic Press
Published Date: 1st October 2018
Page Count: 272
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The Molecular Pathology of Neurodegenerative Disease brings together the current understanding of the molecular basis of neurodegeneration in humans in a form that is targeted not only for neuroscientists, but also for graduate students in neuroscience and the biomedical and biological sciences. There are a large number of existing books covering this subject that are aimed at a clinical audience (both at undergraduate and higher level), however the increasing interest in neurodegeneration for more basic science courses – neuroscientists, biologists, pharmacists and so forth - highlight the need for a book tailored for this audience.

Key Features

  • Presents an up-to-date summary on our current understanding of neurodegeneration at a molecular, cellular and tissue level
  • Includes clinical vignettes so that basic science students can relate underlying molecular processes to clinical symptoms
  • Provides background on the history of neurodegeneration
  • Highlights the state-of-the-art treatment options for each disorder


Neuroscientists, graduate and undergraduate students in biological and biomedical sciences, post-doctoral fellows, researchers

Table of Contents

1. An Introduction to Neurodegeneration

2. Alzheimer’s Disease and Dementia

3. Parkinson’s Disease

4. The Prion Diseases

5. The Motor Neuron Diseases and Amyotrophic Lateral Sclerosis

6. Huntington’s Chorea

7. Multiple Sclerosis


No. of pages:
© Academic Press 2019
Academic Press
Paperback ISBN:

About the Author

Patrick A. Lewis

Dr. Lewis has been involved in research into neurodegeneration for over 15 years, investigating dementia, the prion diseases and, for the last 10 years, Parkinson’s disease. He has published over 50 peer-reviewed publications in the field of neurodegeneration, and organized a number of international conferences on Parkinson’s disease, with a particular focus on Leucine Rich Repeat Kinase 2 (LRRK2). With over a decade of teaching experience, he instructs on a wide range of neuroscience-related topics to both undergraduate and postgraduate students at the University of Reading and University College London.

Affiliations and Expertise

University of Reading, and UCL Institute of Neurology, UK

Jennifer E. Spillane

Dr. Jennifer Spillane is a neurology specialist registrar at the National Hospital for Neurology and Neurosurgery. She completed her PhD at the Institute of Neurology and has published peer-reviewed articles over a wide range of neurological topics. She has experience teaching both undergraduate and post graduate medical students.

Affiliations and Expertise

National Hospital for Neurology and Neurosurgery, UK

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