The Molecular Biology of Ciliated Protozoa

The Molecular Biology of Ciliated Protozoa

1st Edition - December 22, 1986

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  • Editor: Joseph Gall
  • eBook ISBN: 9780323154185

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The Molecular Biology of Ciliated Protozoa covers topics that are unique to ciliates, including major molecular progress, genetics, life history, and development of ciliates. Organized into 11 chapters, it focuses on the importance of ciliated protozoa as experimental organisms. The introductory chapter traces the ups and downs of ciliate biology, emphasizing the prominent role of the ciliates in early studies of cell structure, reproduction, and heredity. The book goes on to discuss ciliate genetics and conjugation, providing the basic biological framework for molecular studies of ciliate. Chapters 4 and 5 cover the nuclear DNA content, sequence, and arrangement of holotrichous and hypotrich ciliates. Chapters 6 to 9 examine the characterization of chromosomal telomeres, ribosomal gene amplification, and chromatin and histone structure using ciliated protozoa as experimental organisms. The final two chapters describe the mating mechanism of two ciliates, Blepharisma japonicum and Euplotes raikovi, and the function of surface antigens of Paramecium ciliate. The book is intended for students and investigators who want to learn more about the ciliated protozoa, particularly, in areas that cover fundamental features of eukaryotic biology.

Table of Contents

  • Preface

    1 Introduction

    I. Ciliates as Experimental Organisms

    II. Nuclear Dimorphism

    III. The Compound Ciliate Cortex

    IV. Behavioral Analysis and the Excitable Membrane

    V. Clonal Aging and the Ciliate Life Cycle

    VI. Mating Types and Cryptic Species

    VII. Social Life and Cellular Interactions

    VIII. Ciliate Origins and Ciliate Affinities

    IX. Breeding Studies and Cytoplasmic Heredity

    X. The New Experimental Ciliatology

    XI. Germplasm Resources

    XII. The Ciliate Literature


    2 Genetic Organization of Tetrahymena

    I. Introduction

    II. Conjugation

    III. Nullisomics and Genetic Maps

    IV. Macronuclear Linkage

    V. Mutagenesis

    VI. Conclusions


    3 Ciliate Conjugation

    I. Conjugation Viewed as a Developmental Program

    II. Nuclear Events of Conjugation

    III. Prezygotic Nuclear Deployments

    IV. Controlled Cell Fusion

    V. Nuclear Fate Determination during Early Postzygotic Development

    VI. Onset of Gene Expression in the Developing Macronucleus

    VII. Evolutionary Aspects of Conjugation and Nuclear Dualism


    4 The Nuclear DNAs of Holotrichous Ciliates

    I. Introduction

    II. Karyotype

    III. DNA Content and Copy Number of DNA Sequences in Micro- and Macronuclei

    IV. Mechanism of DNA Sequence Rearrangements

    V. Function of Micronucleus-Specific DNA Sequences

    VI. Conclusions


    5 The Special Case of the Hypotrichs

    I. Introduction

    II. Organization of the Micronuclear and Macronuclear Genomes

    III. Cytological and Cytochemical Studies of Macronuclear Development

    IV. Organization and Reorganization of the Micronuclear Genome

    V. Structure and Function of Micronuclear and Macronuclear Genomes during Vegetative Growth

    VI. Summary


    6 Telomeres

    I. Introduction

    II. Ciliate Systems for Studying Telomere Structure

    III. Relationship of Ciliate Telomeres to Telomeres of Other Eukaryotes

    IV. Replication of Telomeres in Ciliates and Other Lower Eukaryotes

    V. Formation of New Telomeres in Macronuclear Development

    VI. Unsolved Problems


    7 Amplification of Ribosomal RNA Genes

    I. Introduction

    II. Macronuclear rDNA

    III. Micronuclear rDNA

    IV. Formation of the Extrachromosomal Palindromic rDNA

    V. rDNA of Developing Macronuclei

    VI. Genetic Analysis of rDNA Amplification

    VII. rDNA Amplification in Other Ciliates

    VIII. Summary and Remarks


    8 Ribosomal RNA Gene Expression in Tetrahymena: Transcription and RNA Splicing

    I. Introduction

    II. Transcription and Processing of rDNA in Vivo

    III. Transcription in Vitro

    IV. RNA Splicing in Vitro

    V. Prospectus


    9 Ciliate Chromatin and Histones

    I. Introduction

    II. Chromatin

    III. Histones

    IV. Epilogue


    10 Mating Pheromones

    I. Fore ward

    II. Introduction

    III. Blepharisma japonicum

    IV. Euplotes raikovi

    V. Conclusions and Perspectives


    11 Surface Antigens of Paramecium

    I. Introduction

    II. Background

    III. Serotypes

    IV. Serotype Switching

    V. Cell Biology

    VI. The Proteins, the mRNAs, and the Genes

    VII. The Control of i-Antigen Expression

    VIII. i-Antigen-Associated Systems

    IX. Macronuclear Processing

    X. Coding Problems 7

    XI. i-Antigens in Tetrahymena

    XII. Conclusions



Product details

  • No. of pages: 362
  • Language: English
  • Copyright: © Academic Press 1986
  • Published: December 22, 1986
  • Imprint: Academic Press
  • eBook ISBN: 9780323154185

About the Editor

Joseph Gall

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