The Liver - 1st Edition - ISBN: 9781483228242, 9781483271750

The Liver

1st Edition

Morphology, Biochemistry, Physiology

Editors: Ch. Rouiller
eBook ISBN: 9781483271750
Imprint: Academic Press
Published Date: 1st January 1963
Page Count: 696
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The Liver: Morphology, Biochemistry, Physiology, Volume I focuses on the advancement of knowledge on the liver under normal and pathological conditions, as revealed by morphological and physiological studies. The selection first offers information on the embryonic liver and anatomy of the liver, including morphology and physiology of the embryonic liver, histology of the liver, surgical segments, and vascular gross anatomy of the liver. The text then elaborates on the structure of the liver sinusoids and the sinusoidal cells and the cyto- and histochemistry of the liver. Topics include protein reactions, nucleic acids, glycogen, lipids, heavy metals, and morphological aspects of lining cells.
The publication examines electron microscopy of the liver; acinar units and the pathophysiology of the liver; and dynamics of circulation in the liver. Discussions focus on oxygen transport and consumption in the liver; experimental alterations of the hepatic circulation; hexagonal pattern and the interdigitation of the afferent and efferent vascular trees; and simple liver acinus.
The selection is a dependable source of data for morphologists, biochemists, pharmacologists, and clinicians.

Table of Contents



Contents of Volume II

1. The Embryonic Liver

I. Morphology

II. Embryonic Liver Physiology


2. Anatomy of the Liver

I. Histology of the Liver

II. Vascular Gross Anatomy of the Liver

III. Surgical Segments


3. The Structure of the Liver Sinusoids and the Sinusoidal Cells

I. Historical and Theoretical Considerations

II. Morphological Aspects of Lining Cells

III. The Basement Membrane and the "Space of Disse"

IV. Electron Microscopic Findings


4. Cyto- and Histochemistry of the Liver

I. Introduction

II. Nucleic Acids

III. Protein Reactions

IV. Glycogen

V. PAS-Positive Nonglycogenic Material

VI. Lipids

VII. Heavy Metals

VIII. Enzymatic Staining Reactions

IX. Discussion


5. Electron Microscopy of the Liver

I. Introduction

II. The Hepatic Cell

III. The Biliary Pathways

IV. The Blood Sinusoids, the Kupffer Cell, and the Perisinusoidal Space


6. Acinar Units and the Pathophysiology of the Liver

I. Historical Note on the Microlobulation of the Liver

II. Simple Liver Acinus

III. The Complex Liver Acinus and the Acinar Agglomerate

IV. Hexagonal Pattern and the Interdigitation of the Afferent and Efferent Vascular Trees

V. Pathways of Hepatic Circulation

VI. Lines and Patterns Deriving from the Acinar Units for the Orientation of Hepatic Lesions

VII. Functional Anatomical Interpretation of Classical Notions in Pathology

VIII. Common Lesions in the Structural and Functional Units of the Human Liver

IX. Summary


7. Dynamics of the Circulation in the Liver

I. Methodological Considerations

II. Results of Various Estimations of Hepatic Blood Flow

III. Oxygen Transport and Consumption in the Liver

IV. Hepatic Fractions of the Cardiac Output

V. Hepatic Circulation in Diseases of the Liver

VI. The Portal Pressure

VII. Experimental Alterations of the Hepatic Circulation

VIII. Concluding Remarks


8. The Cell Components of the Liver Isolation, Morphology, Biochemistry

I. Introduction

II. Isolation of Cell Components

III. Morphology of Isolated Fractions

IV. Biochemistry of Isolated Cell Components

V. Conclusions

VI. Appendix: Isolated Liver Cells


9. Metabolism of Amino Acids and Proteins

I. Introduction

II. General Picture of Amino Acid and Protein Metabolism

III. Free Amino Acid Levels: Concentration of Amino Acids by the Liver

IV. The Removal of Nitrogen as Ammonia from Amino Acids

V. Transamination of Amino Acids

VI. Other Mechanisms for the Removal of Nitrogen

VII. Urea Metabolism

VIII. Ammonia Metabolism

IX. Creatine-Creatinine Metabolism

X. Synthesis of Conjugates of Amino Acids

XI. Further Metabolism of Amino Acids

XII. Protein Metabolism


10. The Liver and Lipid Metabolism

I. Introduction: The General Role of the Liver

II. The Hepatic Lipids

III. Metabolism of the Fatty Acids

IV. The Synthesis and the Degradation of Phospholipids

V. The Liver and the Circulating Lipids

VI. The Liver and the Metabolism of Cholesterol


11. The Liver and Carbohydrate Metabolism

I. Introduction

II. Metabolism

III. Carbohydrate Metabolism and Hepatic Conjugation

IV. Energetics of Carbohydrate Metabolism

V. Mechanisms for the Regulation of Carbohydrate Metabolism

VI. Carbohydrate Metabolism as a Function of the Development State of the Organism

VII. Metabolic Diseases Due to Deficiencies in Enzymes of Carbohydrate Metabolism


Author Index

Subject Index


No. of pages:
© Academic Press 1963
Academic Press
eBook ISBN:

About the Editor

Ch. Rouiller

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