The Laboratory Rabbit, Guinea Pig, Hamster, and Other Rodents

The Laboratory Rabbit, Guinea Pig, Hamster, and Other Rodents

1st Edition - December 14, 2011
This is the Latest Edition
  • Editors: Mark Suckow, Karla Stevens, Ronald Wilson
  • eBook ISBN: 9780123809216
  • Hardcover ISBN: 9780123809209

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Description

The Laboratory Rabbit, Guinea Pig, Hamster, and Other Rodents is a single volume, comprehensive book sanctioned by the American College of Laboratory Animal Medicine (ACLAM), covering the rabbit, guinea pig, hamster, gerbil and other rodents often used in research. This well-illustrated reference won a 2012 PROSE Award for Best Single Volume Reference in Science from the Association of American Publishers. The book includes basic biology, anatomy, physiology, behavior, infectious and noninfectious diseases, husbandry and breeding, common experimental methods, and use of the species as a research model. With many expert contributors, this will be an extremely valuable publication for biomedical researchers, laboratory animal veterinarians and other professionals engaged in laboratory animal science.

Key Features

  • 2012 PROSE Award winner for Best Single Volume Reference in Science from the Association of American Publishers
  • One-stop resource for advancements in the humane and responsible care of: rabbit, guinea pig, hamster, gerbil, chinchilla, deer mouse, kangaroo rat, cotton rat, sand rat, and degu
  • Includes up-to-date, common experimental methods
  • Organized by species for easy access during bench research

Readership

The primary audience for this work is biomedical researchers, laboratory animal veternarians, and other professionals engaged in laboratory animal science.

Table of Contents

  • Preface

    List of Contributors

    List of Reviewers

    PART I. General

    Chapter 1. Ethical Considerations and Regulatory Issues

    Introduction

    Ethical Concepts

    Ethical Challenges

    Institutional Animal Welfare Oversight

    Regulations and Non-regulatory Considerations

    Conclusion

    REFERENCES

    Chapter 2. Anesthesia and Analgesia

    Pre-anesthetic Preparation

    Controlled Substances

    Pharmacology

    Anesthesia Circuits

    Anesthesia Monitoring and Support

    Surgical Anesthesia

    Post-operative Monitoring and Pain Assessment

    REFERENCES

    Chapter 3. Clinical Biochemistry and Hematology

    Introduction

    Clinical Biochemistry

    Rabbit

    Guinea Pig

    Hamster

    Other Rodents

    Hematology

    Rabbit

    Guinea Pig

    Hamster

    Other Rodents

    REFERENCES

    Chapter 4. Euthanasia and Necropsy

    Introduction

    Euthanasia

    Necropsy

    Pathology Considerations

    Acknowledgments

    REFERENCES

    Chapter 5. Zoonoses and Occupational Health

    Introduction

    Viral Diseases

    Rickettsial Diseases

    Chlamydial Diseases

    Bacterial Diseases

    Fungal Diseases

    Cestode Infections

    Arthropod Infections

    Allergies

    Prevention of Allergy and Zoonotic Disease

    REFERENCES

    PART II. Rabbits

    Chapter 6. The Domestic Rabbit,

    Introduction and Background

    Phylogeny and Taxonomy

    Geographic Origins and Diversity

    Domestication and Breed Development

    Ecology and Conservation

    REFERENCES

    Chapter 7. Rabbit Genetics and Transgenic Models

    Rabbit Genetics

    Transgenic Rabbits

    Conclusions

    REFERENCES

    Chapter 8. Anatomy, Physiology, and Behavior

    Introduction

    External Features

    Osteology

    Oral Cavity

    Abdominal Viscera

    Urogenital System

    Thoracic Viscera

    Brain and Spinal Cord

    Metabolism

    Behavior

    Acknowledgments

    REFERENCES

    Chapter 9. Rabbit Colony Management and Related Health Concerns

    Introduction

    Laboratory Management

    Breeding

    Nutrition

    Nutritionally Related Diseases

    REFERENCES

    Chapter 10. Basic Experimental Methods in the Rabbit

    Introduction

    Handling and Restraint

    Sampling Techniques

    Compound Administration

    Specialized Research Techniques

    REFERENCES

    Chapter 11. Polyclonal Antibody Production

    Introduction

    The Immunogen

    Immunogen Dose

    Route of Immunization

    Immunization Schedule

    Adjuvants

    Summary

    REFERENCES

    Chapter 12. Toxicity and Safety Testing

    Introduction

    Toxicity Testing

    Safety Testing

    Metabolism and Toxicokinetics

    Acknowledgments

    REFERENCES

    Chapter 13. Bacterial Diseases

    Introduction

    Pasteurellosis

    Enterotoxemia

    Tyzzer’s Disease

    Colibacillosis

    Salmonellosis

    Staphylococcosis

    Treponematosis

    Necrobacillosis

    Listeriosis

    Tuberculosis

    Tularemia

    Proliferative Enteropathy

    Miscellaneous Bacterial Diseases

    REFERENCES

    Chapter 14. Viral Diseases

    Introduction

    DNA Virus Infections

    RNA Virus infections

    REFERENCES

    Chapter 15. Parasitic Diseases

    Introduction

    Protozoa

    Arthropods

    Helminths

    REFERENCES

    Chapter 16. Rabbit Neoplasia

    Introduction

    Neoplasms of Oryctolagus cuniculus

    Neoplasms of Sylvilagus

    Neoplasms of Lepus

    REFERENCES

    Chapter 17. Mycoses and Non-Infectious Diseases

    Introduction

    Mycotic Diseases

    Non-Infectious Diseases

    REFERENCES

    Chapter 18. The Rabbit as an Experimental Model

    Introduction

    Cardiovascular Diseases

    Ophthalmic Diseases

    Central Nervous System Diseases

    Respiratory Diseases

    Urogenital Diseases

    Gastrointestinal Diseases

    Musculoskeletal Diseases

    Multisystemic Diseases

    Acknowledgments

    REFERENCES

    PART III. Guinea Pigs

    Chapter 19. Taxonomy and History

    Introduction

    Taxonomy and Geographical Distribution

    Origin and Domestication

    Genetics

    REFERENCES

    Chapter 20. Anatomy, Physiology, and Behavior

    Introduction

    External Anatomy

    Musculoskeletal System

    Digestive System

    Cardiovascular System

    Pulmonary System

    Genitourinary System

    Nervous System

    Special Senses

    Behavior

    REFERENCES

    Chapter 21. Management, Husbandry, and Colony Health

    Introduction

    Handling

    Housing

    Reproduction and Breeding

    Nutrition

    Colony Health

    Record Keeping

    REFERENCES

    Chapter 22. Basic Experimental Methods

    Introduction

    Handling and Restraint

    Sampling Techniques

    Compound Administration

    Specialized Research Techniques

    REFERENCES

    Chapter 23. Infectious Diseases

    Introduction

    Viral infections

    Bacterial infections

    Fungal infections

    Protozoa infections

    Parasitic infections

    REFERENCES

    Chapter 24. Non-Infectious Diseases

    Introduction

    Cardiovascular System

    Respiratory System

    Gastrointestinal System

    Urinary System

    Endocrine System

    Reproductive System

    Musculoskeletal System

    Integumentary System

    Special Senses

    Hematolymphatic System

    Multisystemic Conditions

    REFERENCES

    Chapter 25. Guinea Pigs as Experimental Models

    Introduction

    Models of Disease

    REFERENCES

    PART IV. Hamsters

    Chapter 26. Taxonomy and History

    Taxonomy

    Geographical Distribution

    Origin and Domestication

    Genetics

    Acknowledgments

    REFERENCES

    Chapter 27. Anatomy, Physiology, and Behavior

    Introduction

    External Features

    Musculoskeletal System

    Digestive System

    Circulatory System

    Pulmonary System

    Genitourinary System

    Nervous System

    Special Senses

    Behavior

    REFERENCES

    Chapter 28. Management, Husbandry, and Colony Health

    Introduction

    Housing

    Environmental Conditions

    Nutrition

    Breeding

    Colony Health

    Record Keeping

    REFERENCES

    Chapter 29. Biomedical Research Techniques

    Introduction

    General Non-Surgical Procedures

    Injections and Intubations

    Biological Specimen Collections

    Other Surgical Procedures

    REFERENCES

    Chapter 30. Bacterial and Fungal Diseases

    Introduction

    Bacterial Diseases

    Fungal Diseases

    REFERENCES

    Chapter 31. Viral Diseases

    Introduction

    DNA Viruses

    RNA Viruses

    Miscellaneous Viruses

    REFERENCES

    Chapter 32. Parasitic Diseases

    Introduction

    Protozoa

    Nematodes

    Arthropods

    REFERENCES

    Chapter 33. Non-Infectious Diseases

    Introduction

    Diseases Associated with Aging

    Nutritional Disorders

    Genetic, Traumatic, Environmental and Other Non-Infectious Diseases

    Neoplasms

    REFERENCES

    Chapter 34. The Experimental Use of Syrian Hamsters

    Introduction

    Cancer Research

    Metabolic Diseases

    Non-Cancerous Respiratory Diseases

    Cardiovascular

    Infectious Disease Research

    Other Models

    REFERENCES

    Chapter 35. The Chinese or Striped-Back Hamster

    Introduction

    Biology

    Care and Husbandry

    Cytogenetics and Fetal Development

    Diseases

    Research Uses

    Summary

    REFERENCES

    Chapter 36. The European Hamster

    Taxonomy

    History

    Biology

    Behavior

    Diseases

    Management, Husbandry, and Colony Health

    Experimental Methodology

    Use in Biomedical Research

    REFERENCES

    Chapter 37. Other Hamsters

    Introduction

    Phodopus sungorus (Djungarian Hamster)

    Mesocricetus brandti (Turkish Hamster)

    Cricetulus migratorius (Armenian Hamster)

    Mesocricetus newtoni (Romanian Hamster)

    REFERENCES

    PART V. Chinchillas

    Chapter 38. Taxonomy and History

    Introduction

    Taxonomy

    History

    REFERENCES

    Chapter 39. Anatomy, Physiology, and Behavior

    Introduction

    External Features

    Unique Biological Characteristics

    Behavior

    REFERENCES

    Chapter 40. Management, Husbandry, and Colony Health

    Introduction

    Housing Systems

    Environmental Conditions

    Nutrition

    Breeding

    Colony Health

    Record Keeping

    REFERENCES

    Chapter 41. Basic Experimental Methods

    Introduction

    Handling and Restraint

    Mechanical Methods

    Sampling Techniques

    Compound Administration

    Specialized Research Techniques

    REFERENCES

    Chapter 42. Diseases and Veterinary Care

    Introduction

    Gastrointestinal and Metabolic Diseases

    Traumatic Lesions

    Management-Related Disorders

    Neoplastic Diseases

    Miscellaneous Conditions

    REFERENCES

    Chapter 43. Chinchillas as Experimental Models

    Introduction

    Models Related to Aural Disease

    Models Related to Hearing Loss

    Future of Chinchilla Models

    REFERENCES

    PART VI. Other Rodents

    Chapter 44. Degu

    Introduction

    History and Taxonomy

    Anatomy, Physiology, and Behavior

    Management, Husbandry, and Colony Health

    Handling and Restraint

    Sampling Techniques

    Compound Administration

    Anesthesia and Analgesia

    Euthanasia and Necropsy

    Diseases

    The Degu as an Experimental Model

    REFERENCES

    Chapter 45. Naked Mole Rat

    History

    Taxonomy

    General Description

    Natural Habitat

    Behavior

    Reproductive Behavior

    General Physiology

    Anatomy and Physiology of Organ Systems

    Aging

    Husbandry

    Colony Health

    Use in Research

    REFERENCES

    Chapter 46. Deer Mice, White-Footed Mice, and their Relatives

    Introduction

    Biology

    Husbandry

    Captive Breeding

    Diseases

    Anesthesia/Analgesia

    REFERENCES

    Chapter 47. Dormouse

    Introduction

    Taxonomy and History (Table 47.1)

    Anatomic Characteristics

    Husbandry

    Nutrition

    Housing

    Environmental Conditions

    Handling

    Breeding

    Diseases and Zoonoses

    Colony Health Monitoring

    Experimental Applications

    Biomethodology

    REFERENCES

    Chapter 48. Kangaroo Rat

    Introduction

    Biology

    Diseases

    Use in Research

    Laboratory Care

    REFERENCES

    Chapter 49. Cotton Rat

    Introduction

    Biology

    Husbandry

    Diseases

    Experimental Methods

    Use in Research

    Acknowledgments

    REFERENCES

    Chapter 50. Pocket Gopher

    Introduction

    Biology

    Diseases

    REFERENCES

    Chapter 51. White-Tailed Rat

    Introduction

    Taxonomy, History, and Genetics

    Anatomy, Physiology, and Behavior

    Management, Husbandry, and Colony Health

    Basic Experimental Methods

    Diseases and Veterinary Care

    Experimental Models

    REFERENCES

    Chapter 52. Gerbils

    Introduction

    Taxonomy and History

    Anatomy, Physiology, and Behavior

    Management, Husbandry, and Colony Health

    Basic Experimental Methods

    Veterinary Care and Diseases

    Gerbils as Experimental Models

    REFERENCES

    Chapter 53. Egyptian Fat-Tailed Jird

    Introduction

    Anatomy, Physiology, and Behavior

    Management, Husbandry, and Colony Health

    Diseases

    Anesthesia/Analgesia, Euthanasia, and Necropsy

    Use in Research

    Basic Experimental Methods

    REFERENCES

    Chapter 54. Sand Rat

    Introduction

    Selection of Reliable Diets and Psammomys Lines for Diabetes Research

    Metabolic Efficiency

    Morphology, Physiology, Breeding Performance, and Husbandry

    The Basis of Diabetes in Psammomys

    The Relevance of Psammomys to Diabetes Research

    The Genetic Basis of Psammomys Diabetes

    Worldwide Research Using Psammomys

    Complications of Diabetes in Psammomys

    Concluding Remarks

    REFERENCES

    PART VII. Formulary and Normative Values

    Chapter 55. Formulary

    Introduction

    Rabbit (Oryctolagus cuniculus)

    Guinea Pig (Cavia porcellus)

    Hamster (Mesocricetus auratus)

    Degu (Octodon degus)

    Other Species

    REFERENCES

    Chapter 56. Normative Values

    Rabbits (Oryctolagus cuniculus)

    Guinea pigs (Cavia porcellus)

    Hamsters

    Gerbils (Meriones unguiculatus)

    Chinchillas (Chinchilla laniger)

    Other rodents

    REFERENCES

    Index

Product details

  • No. of pages: 1288
  • Language: English
  • Copyright: © Academic Press 2012
  • Published: December 14, 2011
  • Imprint: Academic Press
  • eBook ISBN: 9780123809216
  • Hardcover ISBN: 9780123809209
  • About the Editors

    Mark Suckow

    Mark A. Suckow, DVM, DACLAM, is the Associate Vice President for Research, Attending Veterinarian, and Professor of Biomedical Engineering at the University of Kentucky. He is on the council on Accreditation at the Association for Assessment and Accreditation of Laboratory Animal Care International. Dr. Suckow has 25 years of experience with IACUC organization and regulatory compliance, laboratory animal medicine, research with a variety of animal models, and animal facility design and management. He is the previous editor of laboratory animal publications with CRC Press and AP/Elsevier, including Principles of Animal Research, Research Regulatory Compliance and The Laboratory Rabbit, Guinea Pig, Hamster and Other Rodents

    Affiliations and Expertise

    Associate Vice President for Research, Attending Veterinarian, Professor, Biomedical Engineering, University of Kentucky, Lexington, KY.

    Karla Stevens

    Affiliations and Expertise

    Ethicon Endo-Surgery, Inc., Sommerville, NJ, U.S.A.

    Ronald Wilson

    Ronald P. Wilson, VMA, MS, DACLAM, is the Professor and Chair of Comparative Medicine at Pennsylvania State University. Research interests are related to experimental surgery, pain, analgesia and anesthesia of laboratory animals.

    Affiliations and Expertise

    Professor and Chair, Department of Comparative Medicine, Penn State University College of Medicine, Hershey, PA, USA

    Latest reviews

    (Total rating for all reviews)

    • Dr. B. Fri Apr 12 2019

      The Laboratory Rabbit, Guinea Pig, Hamster, and Other Rodents

      Great book for research. And you can find a thousands of authors and publications. Is the money worth.