The Joints and Synovial Fluid

The Joints and Synovial Fluid

Volume II

1st Edition - January 1, 1980

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  • Editor: Leon Sokoloff
  • eBook ISBN: 9781483259628

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The Joints and Synovial Fluid II is a collection of papers that deals with the basic aspects of the articular apparatus, including the general pathology of the appendicular and axial structures, the disease processes, and comparative anthology. Some papers discuss in vitro culture of joints and articular tissues, the chemistry of the ground substance of joint cartilage, and the structure of the intervertebral disc in relation to its function and to the aging process. As a humans being ages, the whole nucleus found in the disc will behave more like a sponge than a shock absorber as regards its ability to distribute stress and pressure from the end plates of the disc. Another paper describes load distribution of the knee, ankle joint, the spine, the arms, elbows, fingers. One paper deals with the pathology of the spine covering infectious diseases, metabolic and developmental disease of cartilage and bones, traumatic and degenerative diseases, autoimmune connective tissue diseases (such as ankylosing spondylitis), and miscellaneous diseases (such as tumors). The collection is suitable for researchers, scientists, medical practitioners, and academicians in the fields of biochemistry, bioengineering, anatomical sciences, immunology, organ physiology, cell biology, orthopedics, rheumatology, or rehabilitation medicine.

Table of Contents

  • List of Contributors


    Contents of Volume I

    1 In Vitro Culture of Joints and Articular Tissues

    I. Organ Culture

    II. Cell Culture

    III. Concluding Remarks


    2 The Chemistry of the Ground Substance of Joint Cartilage

    I. Introduction

    II. General Composition of Cartilage

    III. The Proteoglycans

    IV. Metabolic Control Mechanisms

    V. Degradative Processes

    VI. Glycosaminoglycans of Meniscus and Periarticular Tissues

    VII. Unsolved Problems


    3 Studies of the Structure of the Human Intervertebral Disc in Relation to Its Functional and Aging Processes

    I. Introduction

    II. Protein Structure and Stability

    III. Collagen

    IV. The Protein-Polysaccharide Complexes in Collagen

    V. The Proteoglycans

    VI. The Human Intervertebral Disc—General Configuration

    VII. The Collagen of the Human Intervertebral Disc

    VIII. The Anulus Fibrosus

    IX. The Idealized Disc Mechanism

    X. The Structure of the Nucleus Pulposus

    XI. The Proteins in the Nucleus

    XII. Electron Microscope Studies of the Disc

    XIII. Hydrothermal Stability of Collagen on Aging in the Human Intervertebral Disc

    XIV. General Discussion on Disc Properties and Their Changes with Age


    Supplementary References

    4 Joint Kinetics

    I. Joint Movements

    II. Mechanisms of the Leg and Hip Joint Loading

    III. Knee and Ankle Joint Loading

    IV. Loading of Joints of the Upper Extremity

    V. The Spine

    VI. Joint Pressures

    VII. Experimental Methods


    5 Th4e Mechanical Properties of Articular Cartilage

    I. Introduction

    II. Engineering Terminology

    III. The Mechanical Functions of Cartilage


    6 Physical Chemistry of Articular Cartilage and the Intervertebral Disc

    I. Matrix Characteristics

    II. Solute Transport

    III. Turnover Studies

    IV. Fluid Transport


    7 The Physiology of the Normal Synovium

    I. Intraarticular Pressure

    II. Synovial Fluid Po2, PCO2, pH, Lactic Acid, and Glucose Content

    III. Synovial Blood Flow

    IV. Transynovial Exchange of Small Molecules

    V. Conclusions


    8 General Pathology of the Peripheral Joints

    I. Introduction

    II. Heritable Disease

    III. Acquired Disease


    9 The Pathology of the Spine

    I. Introduction

    II. Vascular Supply

    III. Growth and Development of the Spine

    IV. Infectious Spondylitis

    V. Metabolic and Developmental Disease

    VI. Structural Diseases of the Spine

    VII. Aging and Degenerative Disease in the Spine

    VIII. Bursae of the Spine and Their Relationship to Movement and Inflammatory Disease

    IX. Psoriasis and Spondylitis

    X. Ulcerative Colitis and Crohn's Disease with Spondylitis

    XI. Spinal Involvement in Juvenile Chronic Polyarthritis

    ΧII. Spinal Changes in Rheumatoid Arthritis

    ΧIII. The Spinal Changes in Ankylosing Spondylitis (AS)

    XIV. Tumors of the Spine

    XV. Conclusions



Product details

  • No. of pages: 578
  • Language: English
  • Copyright: © Academic Press 1980
  • Published: January 1, 1980
  • Imprint: Academic Press
  • eBook ISBN: 9781483259628

About the Editor

Leon Sokoloff

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