The Histamine H3 Receptor - 1st Edition - ISBN: 9780444829368, 9780080534008

The Histamine H3 Receptor, Volume 30

1st Edition

A Target for New Drugs

Editors: R. Leurs H. Timmerman
Hardcover ISBN: 9780444829368
eBook ISBN: 9780080534008
Imprint: Elsevier Science
Published Date: 9th December 1998
Page Count: 290
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Table of Contents

Preface. Subclassification of histamine receptors, H3-receptor subtypes? Localization of H3 receptors in the brain (J.M. Arrang et al.). Modulation of in vitro neurotransmission in the CNS and in the retina via H3 heteroreceptors (E. Schlicker, M. Kathmann). H3 receptor modulation of the release of neurotransmitters in vivo (P. Blandina et al.). H3 receptor modulation of neuroendocrine responses to histamine and stress (U. Knigge et al.). Functional role of histamine H3 receptors in peripheral tissues (G. Bertaccini et al.). Biochemical properties of the histamine H3 receptor (M. Hoffman et al.). Radioligands for the histamine H3 receptor and their use in pharmacology (F.P. Jansen et al.). Substituted imidazoles, the key to histaminergic receptors (W.M.P.B. Menge, H. Timmerman). Synthesis of radioligands for the histamine H3 receptor (A.D. Windhorst et al.). Medicinal chemistry of histamine H3 receptor antagonists (J.G. Phillips, S.M. Ali). Molecular modelling studies of histamine H3 receptor ligands (I.J.P. de Esch et al.). Brain histamine in pathophysiological conditions and brain diseases (P. Panula et al.). Histamine H3 antagonists as potential therapeutics in the CNS (K. Onodera, T. Watanabe). Clinical application of HA H3 receptor antagonists in learning and memory disorders (C.E. Tedford).


Description

Preface. Subclassification of histamine receptors, H3-receptor subtypes? Localization of H3 receptors in the brain (J.M. Arrang et al.). Modulation of in vitro neurotransmission in the CNS and in the retina via H3 heteroreceptors (E. Schlicker, M. Kathmann). H3 receptor modulation of the release of neurotransmitters in vivo (P. Blandina et al.). H3 receptor modulation of neuroendocrine responses to histamine and stress (U. Knigge et al.). Functional role of histamine H3 receptors in peripheral tissues (G. Bertaccini et al.). Biochemical properties of the histamine H3 receptor (M. Hoffman et al.). Radioligands for the histamine H3 receptor and their use in pharmacology (F.P. Jansen et al.). Substituted imidazoles, the key to histaminergic receptors (W.M.P.B. Menge, H. Timmerman). Synthesis of radioligands for the histamine H3 receptor (A.D. Windhorst et al.). Medicinal chemistry of histamine H3 receptor antagonists (J.G. Phillips, S.M. Ali). Molecular modelling studies of histamine H3 receptor ligands (I.J.P. de Esch et al.). Brain histamine in pathophysiological conditions and brain diseases (P. Panula et al.). Histamine H3 antagonists as potential therapeutics in the CNS (K. Onodera, T. Watanabe). Clinical application of HA H3 receptor antagonists in learning and memory disorders (C.E. Tedford).


Details

No. of pages:
290
Language:
English
Copyright:
© Elsevier Science 1998
Published:
Imprint:
Elsevier Science
eBook ISBN:
9780080534008
Hardcover ISBN:
9780444829368

About the Editors

R. Leurs Editor

H. Timmerman Editor