The HDL Handbook
Biological Functions and Clinical Implications
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The HDL Handbook: Biological Functions to Clinical Implications brings laboratory research in HDL from bench to bedside in this needed resource for researchers and clinicians studying cholesterol, lipids, epidemiology, biochemistry, molecular medicine, and pathophysiology of cardiovascular diseases. In addition, researchers and clinicians working with an aging population, corporate researchers, post-doctorates; medical students and graduate students will find this publication useful because the scope of coverage includes basic science, genetics, epidemiology, and treatment of HDL cholesterol as well as potential targets to modify HDL cholesterol.
Key Features
- Comprehensive coverage of basic science, genetics, epidemiology and treatment
- Reputable content on latest advances in HDL cholesterol research
- Inclusive, worldwide content with country specific information
- In depth discussion of potential targets to modify HDL
Readership
The primary audience for this work is researchers and clinicians studying cholesterol, lipids, epidemiology, biochemistry, molecular biology, molecular medicine, and pathophysiology of cardiovascular diseases; researchers and clinicians working with an aging population; corporate researchers; postdocs; medical students and graduate students.
The secondary audience is allied health professionals, nurses, and researchers and clinicians studying nutrition.
Table of Contents
Introduction
- Role of phospholipid transfer protein (PLTP) in HDL remodelling and Atherosclerosis
- The role of CETP in HDL metabolism
- The physiological role of CETP in HDL molecule metabolism
- HDL and reverse cholesterol transport: Physiological modulation
- Serum Paraoxonase PON1 and its interactions with HDL: Relationship between PON1 and oxidative stress
- Paraoxonase PON1 and its interaction with HDL: Molecular structures of PON1 and HDL
- Apoliopoprotein A-I mutations
- The Scavenger Receptor Class B Type I: An HDL Receptor Involved in Lipid Transport and HDL Dependent Signaling
- HDL and its mimetic peptides: Novel therapeutic strategies for the treatment of inflammatory vascular disease
- Sterol efflux by ABCA1 and ABCG1
- Possible roles of oxidized HDL: Structural change of HDL particle by oxidative modification and its contribution to vascular diseases
- Pre¿1-HDL: Conversion to and from spherical ¿-migrating HDL in human plasma
- Determination of circulating native and denaturated HDL concentrations and its clinical implications
Product details
- No. of pages: 296
- Language: English
- Copyright: © Academic Press 2010
- Published: August 12, 2010
- Imprint: Academic Press
- eBook ISBN: 9780123821720
About the Editor
Tsugikazu Komoda
Dr. Komoda is a visiting professor at Toho University School of Medicine in Japan. He has extensive expertise with research in alkaline phosphatase, amylase, and oxidized HDL. He co-operated the intestinal alkaline phosphatase at Washington University School of Medicine in St. Louis, Missouri. He is the recipient of the Kodama Memorial Award from Japanese Society of Electrophoresis.
Affiliations and Expertise
Visiting Professor, Toho University School of Medicine, Japan