The Evaluation of Toxicological Data for the Protection of Public Health - 1st Edition - ISBN: 9780080219981, 9781483140087

The Evaluation of Toxicological Data for the Protection of Public Health

1st Edition

Proceedings of the International Colloquium, Luxembourg, December 1976

Editors: W. J. Hunter J. G. P. M. Smeets
eBook ISBN: 9781483140087
Imprint: Pergamon
Published Date: 1st January 1977
Page Count: 428
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The Evaluation of Toxicological Data for the Protection of Public Health: Proceedings of the International Colloquium, Luxembourg, December 1976 focuses on the review of toxicological tests and methods used in toxicological evaluation of chemicals and reconsideration of these procedures in identifying decision-making processes involved in the protection of public health. The selection first discusses reviews of toxicological tests, including introductory remarks and comments on acute toxicity; problems associated with the testing of environmental mutagens; and the testing of carcinogenic potentials. The publication also examines the uncertainties related to the evaluation of the health hazards of environmental chemicals from toxicological data and epidemiological monitoring of indices of chemical hazards.
The book takes a look at safety factors and their application in toxicological evaluation; ecotoxicological approaches for the protection of environment and health; and use of biological materials as environmental pollution gauges. The text also discusses acute toxicity, teratogenic effects of pollutants, and examples of ecotoxicological research.
The selection is a dependable source of data for readers interested in the evaluation of toxicological data relative to the protection of public health.

Table of Contents


Editorial Note

Opening Session

Allocution D'ouverture

Opening Address

Introductory Report

Esposto Di Apertura

Introductory Report

Introductory Report

Critical Review of Toxicological Tests Currently in Use


Some Problems Associated with the Testing of Environmental Mutagens

A Critical Review of the Present State of the Testing for Carcinogenic Potentials

Influence De L'environnement Sur la Descendance

Influence of Environmental Factors On Offspring

Critical Review of Evaluation of Toxicological Data


Uncertainties Associated with the Evaluation of the Health Hazards of Environmental Chemicals From Toxicological Data

Critical Review of Evaluation of Toxicological Data: Biochemical Parameters

Morphologic Parameters of Hepatic Injuries

Epidemiological Monitoring of Indices of Chemical Hazards

Critical Review of the Concepts of Safe Levels


Critical Groups and the Size of the Population to be Considered for Pollutant Criteria

Problemès Que Pose Le Concept Du Seuil Dans L'évaluation Du Risque Radioactif

The Problems of the Threshold Level Concept in the Evaluation of Radioactivity Hazards

Safety Factors and Their Application in the Toxicological Evaluation

Ecotoxicological Approaches for the Protection of Environment and Health


Occurrence and Fate of Synthetic Chemicals in the Environment

The Use of Biological Materials as Environmental Pollution Gauges

Examples of Ecotoxicological Research

Ecotoxicology: Some Complexities of Effects on Ecosystems

Other Contributions

Acute Toxicity

Teratogenic Effects of Environmental Pollutants

The Role of the Administrator

Summary and Conclusions


Ecotoxicologie: Objectifs, Principes Et Perspectives

Ecotoxicology: Objectives, Principles and Perspectives

Statement on Behalf of the Food and Agriculture Organization

List of Participants


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© Pergamon 1977
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About the Editor

W. J. Hunter

J. G. P. M. Smeets

Ratings and Reviews