The Brain as a Drug Target

The Brain as a Drug Target

1st Edition - January 12, 2011

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  • Editor: Shafiqur Rahman
  • eBook ISBN: 9780123855077
  • Hardcover ISBN: 9780123855060

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The brain is protected by the blood-brain barrier and this barrier prevents many drugs from entering the brain. This volume discusses various drug delivery and targeting strategies that are being developed to enhance the transport and distribution of drugs into the brain.

Key Features

  • Discusses new discoveries, approaches, and ideas
  • Contributions from leading scholars and industry experts
  • Reference guide for researchers involved in molecular biology and related fields


Researchers, professors and graduate students in biochemistry, chemistry, molecular biology, biotechnology, and medicine

Table of Contents

  • 1. Monoamine Transporters: Vulnerable and Vital Doorkeepers
    Zhicheng Lin, Juan J. Canales, Thröstur Björgvinsson, Morgane M. Thomsen, Hong Qu, Qing-Rong Liu, Gonzalo E. Torres, and S. Barak Caine
    2. Therapeutic Targets in Alzheimer Disease and Related Tauopathies
    Christopher P. Corbo and Alejandra del C. Alonso
    3. Therapeutic Targets for Neuroprotection and/or Enhancement of Functional Recovery Following Traumatic Brain Injury
    Matthew L. Kelso and James R. Pauly
    4. Insulin, Synaptic Function, and Opportunities for Neuroprotection
    John G. Mielke and Yu-Tian Wang
    5. Molecular Alterations in Glioblastoma: Potential Targets for Immunotherapy
    Azizul Haque, Naren L. Banik, and Swapan K. Ray
    6. Molecular Signaling and Translational Significance of the Corticotropin Releasing Factor System
    Patrick J. Ronan, and Cliff H. Summers
    7. Molecular targets of alcohol action: translational research for pharmacotherapy development and screening
    Giorgio Gorini, Richard L. Bell, and R. Dayne Mayfield
    8. Brain Nicotinic Receptors as Emerging Targets for Drug Addiction: Neurobiology to Translational Research
    Shafiqur Rahman
    9. Glutamatergic Neuroplasticity in Cocaine Addiction
    Joachim D. Uys and Kathryn J. Reissner
    10. Role of the serotonergic system in alcohol dependence: from animal models to clinics
    Verity R. Johnson, Jason M. Weedman, Youssef Sari

Product details

  • No. of pages: 468
  • Language: English
  • Copyright: © Academic Press 2011
  • Published: January 12, 2011
  • Imprint: Academic Press
  • eBook ISBN: 9780123855077
  • Hardcover ISBN: 9780123855060

About the Editor

Shafiqur Rahman

Shafiqur Rahman, Ph.D. is Professor of Pharmacology in the Department of Pharmaceutical Sciences at South Dakota State University (SDSU) in Brookings, USA. He received his Ph.D. in Neuropharmacology from the Memorial University of Newfoundland, Canada. Dr. Rahman completed his post-doctoral fellowship in the Department of Psychiatry from Indiana University School of Medicine in Indianapolis in USA. Prior to joining SDSU, he worked as research scientist and faculty at the University of Kentucky in Lexington, USA and the University of Toronto, Canada. Dr. Rahman's research focus is drug discovery in neuropharmacology, i.e. the development of novel therapeutic candidates for the treatment of drug addiction and neuropsychiatric disorders. His research and scholarship has resulted in over 125 publications and 11 edited books/book chapters. Dr. Rahman served as editor, editorial board member and reviewer for numerous Scientific Journals and review panels related to drug addiction, neuropharmacology, and drug discovery research. Dr. Rahman is also a member of several professional societies or organizations, including Society for Neuroscience, American Society for Experimental Neurotherapeutics, and American Society for Pharmacology and Experimental Therapeutics.

Affiliations and Expertise

Professor, Department of Pharmaceutical Sciences, College of Pharmacy, South Dakota State University, Brookings, SD, USA

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