The Biochemistry of Foreign Compounds

The Biochemistry of Foreign Compounds presents the various aspects of biochemistry of foreign compounds in relation to toxicology, pathology, and pharmacology. This book discusses the classification of foreign compounds according to usage, namely, food additives, drugs, pesticides, industrial chemicals, and natural foreign compounds. Organized into two sections encompassing 12 chapters, this book starts with the absorption and secretion of foreign compounds. This text then discusses the two phases of reaction in the metabolism of foreign compounds. Other chapters consider the rate at which each reaction proceeds wherein its relative significance may be affected by many factors that may result in changes in the pattern of metabolism and differences in toxicity. This book discusses as well the physiological factors that affect metabolism, including age, sex, pregnancy, disease, and the nutritional state of the animal. The final chapter deals with the metabolism of some of the commonly used industrial chemicals. This book is a valuable resource for biochemists, chemists, toxicologists, pharmacologists, and pathologists.

Preface

Foreword

Section I. Biochemical Mechanisms

Chapter 1. Introduction

Chapter 2. Absorption, Excretion and Tissue Distribution

Chapter 3. Metabolic Transformations Catalyzed by Hepatic Microsomal Enzymes

Chapter 4. Other Metabolic Transformations

Chapter 5. Conjugation Mechanisms

Chapter 6. Factors Affecting the Metabolism of Foreign Compounds

Chapter 7. Comparative Metabolism

Section II. Applications

Chapter 8. Foreign Compounds of Natural Origin

Chapter 9. Food Additives

Chapter 10. Drugs

Chapter 11. Pesticides

Chapter 12 Industrial Chemicals

List of References

Author Index

Subject Index