The Antigens

List of Contributors

Preface

Contents of Other Volumes

Chapter 1 Dynamic Aspects of Antibody Function

I. Introduction

II. Structure of Immunoglobulins

III. Folding of Immunoglobulin Domains

IV. The Association between Domains and Chains

V. Dynamics of Segmental Flexibility

VI. Kinetics of Antibody-Hapten Association

VII. Kinetic Expression of Elementary Interactions

VIII. Conformational Transitions Induced by Hapten Binding

References

Chapter 2 Parasite Antigens and Their Immunogencity in Infected Hosts

I. Introduction

II. Classification of Parasite Antigens

III. Accessibility of Parasite Antigens

IV. Some Parasite Antigens and Antigenic Preparations with Proved Immunoparasitological Unity and for Which Some Immunochemical Information Is Available

V. Concluding Comment: Parasite Immunochemistry in the Early 1980's

References

Chapter 3 Immunological Tolerance

I. Introduction

II. General Methodology

III. Tolerance Induction

IV. Tolerance Duration

V. The Effect of Tolerance on the Specificity of the Immune Response

VI. Tolerance at the Cellular Level

VII. Mechanism and Molecular Basis of Unresponsiveness—Pathways of Inhibition

VIII. Split Tolerance

IX. The Effect of External Agents on Tolerance Induction

X. Cellular Aspects of Tolerance Circumvention

XI. Tolerance and Immunity to Autologous Molecules

XII. Barriers against Destruction of the Fetus

XIII. Animal Models for Autoimmunity

XIV. Autoimmune Disease

XV. Tolerance as a Potential Tool for Heterotransplantation

XVI. Concluding Remarks

References

Author Index

Subject Index