The Alkaloids, Volume 72

1st Edition

Serial Volume Editors: Hans-Joachim Knölker
Hardcover ISBN: 9780124077744
eBook ISBN: 9780124078529
Imprint: Academic Press
Published Date: 1st March 2013
Page Count: 310
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Table of Contents



Chapter One. Lycopodium Alkaloids – Synthetic Highlights and Recent Developments

1 Introduction

2 General Background

3 Isolation of Lycopodium Alkaloids and Their Biological Properties

4 Total Synthesis of Lycopodium Alkaloids – Historic Aspects

5 Total Synthesis of Lycopodium Alkaloids – Recent Developments

6 Conclusion



Chapter Two. Cephalostatins and Ritterazines

list of Abbreviations

1 Introduction

2 Occurrence

3 Sample Collection and Isolation. Structures and Properties of Bis-steroidal Pyrazine Alkaloids

4 Structure–Activity Relationship

5 Pyrazine Synthesis

6 Synthesis of Common Core Units

7 Synthesis of Cephalostatins and Ritterazines by Coupling of Left and Right Halves

8 Synthesis of Cephalostatin and Ritterazine Analogs

9 Physical and Spectral Data of Cephalostatins and Ritterazines

10 Summary


Cumulative Index of Titles



This series is world-renowned as the leading compilation of current reviews of this vast field. Internationally acclaimed for more than 40 years, The Alkaloids, founded by the late Professor R.H.F. Manske, continues to provide outstanding coverage of this rapidly expanding field. Each volume provides, through its distinguished authors, up-to-date and detailed coverage of particular classes or sources of alkaloids.

Key Features

  • Up-to-date reviews on a large and very important group of natural products from both a chemical and biological perspective
  • Comprehensive, dynamic reviews written by leading authors in the respective fields
  • Broad coverage on the biological aspects


Chemists, biochemists, and pharmacologists


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© Academic Press 2013
Academic Press
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About the Serial Volume Editors

Hans-Joachim Knölker Serial Volume Editor

Curriculum Vitae: Hans-Joachim Knölker born on July, 29th 1958 in Rehren (Germany) ________________________________________________________________________________ 10.1978 – 02.1983 Chemistry studies at the Universities of Göttingen and Hannover; diploma thesis on “Regioselective Transformations of Bicyclo[3.3.0]octanes” in the research group of Prof. Dr. E. Winterfeldt, University of Hannover 03.1983 – 05.1985 Ph.D. thesis on "Stereoselective Cyclopentanone Annulations" with Prof. E. Winterfeldt at the University of Hannover 12.1985 – 12.1986 Postdoctoral studies with Prof. K. P. C. Vollhardt at the Department of Chemistry, University of California, Berkeley, USA, working on "Cobalt-Mediated [2+2+2] Cycloadditions of Imidazoles" 01.1987 – 02.1990 Habilitation at the University of Hannover on "Transition Metal-Mediated Syntheses of Heterocycles" 03.1990 ADUC award 1989 of the German Chemical Society 07.1990 Lecturer award of the Fund of German Chemical Industry 01.1991 Gerhard-Hess award of the Deutsche Forschungsgemeinschaft (DFG) 02.1991 Offer of a professorship for Organic Chemistry at the University of Münster 02.1991 Offer of a chair for Organic Chemistry at the University of Karlsruhe 04.1991 Offer of a professorship for Organic Chemistry at the University of Bonn 05.1991 Offer of a chair for Organic Chemistry at the University of Marburg 08.1991 – 11.2001 Full professor of Organic Chemistry at the University of Karlsruhe 10.1995 – 09.1997 Chairman of the Chemistry Department at the University of Karlsruhe 10. – 11.1998 Visiting professor at the University of Tsukuba, Japan, as fellow of the Japan Society for the Promotion of Science (JSPS) 01.2000 Visiting professor in India on invitation of the Indian National Science Academy (INSA) 11.2000 Offer of a chair of Organic Chemistry at the Technical University of Dresden 02.2001 Offer of the Regius Chair of Chemistry at the University of Glasgow 07.2001 Offer of a chair in Synthetic Organic Ch

Affiliations and Expertise

Department of Chemistry, Technical University of Dresden, Germany