Textbook of Medicinal Chemistry Vol II - 1st Edition - ISBN: 9788131221907, 9788131232590

Textbook of Medicinal Chemistry Vol II

1st Edition

Authors: V Alagarsamy
Paperback ISBN: 9788131221907
eBook ISBN: 9788131232590
Imprint: Elsevier India
Published Date: 25th October 2009
Page Count: 548

Description

Dr Alagarsamy's Textbook of Medicinal Chemistry is a much-awaited masterpiece in its arena. Targeted mainly to B. Pharm. students, this book will also be useful for M. Pharm. as well as M. Sc. organic chemistry and pharmaceutical chemistry students. It aims at eliminating the inadequacies in teaching and learning of medicinal chemistry by providing enormous information on all the topics in medicinal chemistry of synthetic drugs.

Key Features

Salient Features

    • Contains clear classification, synthetic schemes, mode of action, metabolism, assay, pharmacological uses with the dose and structure–activity relationship (SAR) of the following classes of drugs:
      • Drugs acting on inflammation
      • Drugs acting on respiratory system
      • Drugs acting on digestive system
      • Drugs acting on blood and blood-forming organs
      • Drugs acting on endocrine system

    • Contains a complete section on chemotherapy and the various classes of chemotherapeutic agents. Also includes recent topics like anti-HIV agents
    • Contains brief introduction about the physiological and pathophysiological conditions of diseases and their treatment under each topic
    • Provides well-illustrated synthetic schemes and alternative synthetic routes for majority of drugs that help in quick and enhanced understanding of the subject
    • Covers the syllabi of majority of Indian universities

Table of Contents

Preface v

Acknowledgements vii

SECTION I Drugs Acting on Inflammation/Allergy 1

Chapter 1 Antihistamines 3

• Structure–Activity Relationship—H1 Receptor

Antagonists • Classification • Synthesis and Drug Profile

Chapter 2 Prostaglandins 46

• Functions of PGs • Biosynthesis • Synthesis

and Drug Profile

Chapter 3 Analgesics, Antipyretics, and NSAIDs 56

• Classification • SAR of Salicylates; Synthesis

and Drug Profile; SAR of p-Amino Phenol

Derivatives; SAR of 3,5-Pyrazolidine Diones;

SAR of Anthranilic Acid Derivatives;

SAR of Aryl Alkanoic Acid Derivatives;

SAR of Indole Acetic Acid Derivatives; SAR of Oxicams

SECTION II Drugs Acting on Respiratory System 107

Chapter 1 Expectorants and Antitussives 109

• Introduction to Respiratory System • Expectorants and

Antitussives • Classification • Synthesis and Drug Profile

Section III Drugs Acting on Digestive System 119

Chapter 1 Antiulcer Agents 121

• Classification • Synthesis and Drug

Profile • SAR of H2-Receptor Antagonists

Chapter 2 Antidiarrhoeals 137

• Synthesis and Drug Profile

SECTION IV Drugs Acting on Blood and Blood-Forming Organs 143

Chapter 1 Coagulants 145

• Classification • Anticoagulants;

Classification; Synthesis and Drug Profile

Chapter 2 Plasma Expanders 160

SECTION V Drugs Acting on Endocrine System 163

Chapter 1 Oral Hypogylcaemic Drugs 165

• Classification • Synthesis and Drug

Profile • SAR of Sulphonyl Ureas

Chapter 2 Steroids 192

• Steroid Nomenclature and Structure

• Proge

Details

No. of pages:
548
Language:
English
Copyright:
© Elsevier India 2009
Published:
Imprint:
Elsevier India
eBook ISBN:
9788131232590
Paperback ISBN:
9788131221907

About the Author

V Alagarsamy