This volume of Advances in Insect Physiology contains comprehensive interdisciplinary reviews on basic and practical aspects relevant to major target receptors for crucial physiological functions and mechanisms in prokaryotic and eukaryotic organisms, particularly insects. Chapters emphasize advanced genomic, molecular biology, chemical, and proteomic research on the receptors and their corresponding agonist and antagonist ligands. The book encompasses target systems such as sodium channels, octopamine/tyramine receptors, ABC transporters, acetylcholinesterase as a target enzyme, juvenile hormone receptors, and receptors targeted by neuropeptides.

Key Features

  • Contains important, comprehensive and in-depth reviews
  • An essential reference source for invertebrate physiologists and neurobiologists, entomologists, zoologists, and insect biochemists
  • First published in 1963, this serial is ranked second in the highly competitive ISI category of Entomology


Entomologists, zoologists, insect biochemists, insect physiologists

Table of Contents

  • Preface
  • Chapter One: ABC Transporters and Their Role in Protecting Insects from Pesticides and Their Metabolites
    • Abstract
    • 1 Introduction
    • 2 Structural Insights into the Mode of Action of ABC Transporters
    • 3 Evolution of ABC Transporters in Insects
    • 4 Physiological Functions and Metabolic Substrates in Insects
    • 5 Elimination of PSMs
    • 6 ABC Transporters and Insecticide Resistance
    • 7 ABC Transporters as Targets for Pest Control and Resistance Management
    • 8 Concluding Remarks
    • Acknowledgements
  • Chapter Two: Molecular Signalling, Pharmacology, and Physiology of Octopamine and Tyramine Receptors as Potential Insect Pest Control Targets
    • Abstract
    • 1 Introduction
    • 2 OA and TA
    • 3 Molecular Entity and Signal Transduction
    • 4 Pharmacology
    • 5 Physiology
    • 6 Summary and Future Perspectives
    • Acknowledgements
  • Chapter Three: Receptors for Neuronal or Endocrine Signalling Molecules as Potential Targets for the Control of Insect Pests
    • Abstract
    • 1 Introduction
    • 2 GPCRs and Their Functions in Signal Transduction Pathways
    • 3 (Neuro)peptides and Their Receptors: Possible Targets for Insect Pest Control
    • 4 Muscarinic Acetylcholine and Biogenic Amine Receptors
    • 5 Applicability of Neurohormone Receptors as Targets for Insecticides
    • 6 Concluding Remarks
    • Acknowledgements
  • Chapter Four: The Juvenile Hormone Receptor and Molecular Mechanisms of Juvenile Hormone Action
    • Abstract
    • 1 Introduction
    • 2 JH Signalling Through Membrane-Bound Receptors
    • 3 USP: An Intracellular MF Receptor
    • 4 MET: An Intracellular JH Receptor
    • 5 JH Target Genes
    • 6 Crosstalk of Signalling Pathways
    • 7 Concluding Remarks
    • Acknowledgements
  • Chapter Fiv


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© 2014
Academic Press
eBook ISBN:
Print ISBN:

About the serial-volume-editor

Ephraim Cohen

Affiliations and Expertise

Robert H. Smith Faculty of Agriculture, Food and Environment, The Hebrew University of Jerusalem, Rehovot, Israel