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Tantalizing Therapeutics in Bronchopulmonary Dysplasia is a concise reference that provides an overview of emerging concepts in the understanding of lung development and injury from a molecular and cellular point-of-view, including exciting pathways that are paving the way for new options to prevent or treat Bronchopulmonary Dysplasia (BPD). The book's chapters are written by experts who are at the forefront of BPD research. Coverage includes chapters on exosomes, stem cells and miRs, as well as a section on new discoveries in BPD research with translational potential. This is a must-have reference for researchers, physicians and trainees working on BPD, lung developmental biology, and more.
- Includes discussions on which aspects of the bench research in Bronchopulmonary Dysplasia are the most promising areas
- Offers insights into the latest research being conducted that could potentially move to the bassinet (in the NICU)
- Contains evidence-based summaries and informed opinions about existing therapies
Researchers and physicians interested in diseases of the developing lung, including trainees (scientists doing their MS degrees, PhD-candidates pediatric residents and neonatal fellows)
Section 1: Current Therapeutics: State of the Art
1. Systemic and topical glucocorticoids to prevent BPD
Kristi Watterberg and Olivier Baud
2. Use of caffeine for prevention of BPD
Abhay Lodha, Stefani Doucette, and Vineet Bhandari
3. Next Generation ventilator strategies to prevent/manage BPD
Martin Keszler and Ashish Gupta
Section 2: Ongoing Therapeutic Studies with Translational Potential
4. End points for therapeutic trials for BPD: lessons learned from clinical trials
Judy L. Aschner and Cynthia T. McEvoy
5. What can exogenous surfactant provide in the fight against BPD?
Peter A. Dargaville
6. Stem cells in the treatment of BPD
So Yoon Ahn, Yun Sil Chang, Won Soon Park
Section 3: Future Therapeutic Directions
7. Extracellular vesicles in the therapy of BPD
Flore Lesage and Bernard Thebaud
8. Growth factors in the therapy of BPD
Heber C. Nielsen, Anne Chetty, and Vineet Bhandari
9. Antenatal approaches in the therapy of BPD
Andre Gie, Ignacio Valenzuela, Thomas Salaets, Jan Deprest, and Jaan Toelen
10. miRs –mere hype or master regulators in the therapy of BPD?
Charitharth Vivek Lal, Vivek Shukla, Namasivayam Ambalavanan, and Vineet Bhandari
11. Immune modulators for the therapy of BPD
Margaret Gilfillan and Vineet Bhandari
- No. of pages:
- © Academic Press 2020
- 2nd June 2020
- Academic Press
- eBook ISBN:
- Paperback ISBN:
Dr. Bhandari is the Division Head of Neonatology at The Children’s Regional Hospital at Cooper/Cooper Medical School of Rowan University, Camden, NJ. He previously served as a Professor in the Department of Pediatrics at Drexel University College of Medicine, Philadelphia, PA and an Associate Professor of Pediatrics and Obstetrics, Gynecology and Reproductive Sciences at Yale University School of Medicine, New Haven, CT. Dr. Bhandari has been awarded three patents, with a fourth pending. He is an Associate Editor of Pediatric Research, BMC Pediatrics, Frontiers in Pediatrics and Internet Journal of Medical Update. He is on the editorial board of Journal of Perinatology. He has also served as Guest Editor, Managing Editor and Contributing Editor of several other publications. He is a manuscript reviewer for almost 100 research publications and has published over 290 peer-reviewed articles and chapters in books.
Department of Pediatrics (Neonatology), The Children’s Regional Hospital at Cooper/Cooper Medical School of Rowan University, Camden, NJ
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