"Sun Protection in Man" looks at the beneficial and harmful effects of solar radiation. The physiological consequences of sun exposure have been systematically studied starting at the end of the nineteenth century and we now have accumulated knowledge about how Caucasian and Asian skins reacts to solar radiation. The chemical effects of solar ultraviolet radiation have been analyzed with particular emphasis during the second half of the twentieth century. Research on micro-organisms has allowed us to understand the mechanisms of UV-induced mutagenesis and photosensitization. Studies with laboratory rodents have opened the path to the understanding of UV-induced immune-depression, carcinogenesis, photo-damage and photo-aging. The results of these studies have enabled other scientists to investigate the same phenomena in human organs such as the skin and the eye. UV radiation damages hair, as well. The present knowledge in these fields is summarized in some of the chapters of this monograph.
Mass phenomenon in Europe with the generalization of summer vacations which were a consequence of social reforms introducing the concept of "paid vacations". This created a need for protection and opened a market for sunscreens.
This monograph is concerned with sun protection as a whole and is not just "another book on sunscreens". Nonetheless, in these days of general concern, it is important to learn about the efficiency of sunscreens. Several authors discuss how to reduce the number of impinging photons and explain why sunscreens seem to offer less protection than expected. Guidelines are given on how to use sunscreens in everyday life, which are expressed rigorously though clearly, for access to the common reader.
Our knowledge on the relationship between sun and humans is at the early stages of development. Industrial and commercial activities are concerned by the development of this k


For chemists, biochemists and dermatologists with an interest in photobiology, pharmacy and photomedicine.

Table of Contents

Chapter headings. Preface. Historical Perspective. Women (and men) and sun in ancient times (P.U. Giacomoni). The Advantages of Sunlight. A perspective on the beneficial effects of moderate exposure to sunlight: bone health, cancer prevention, mental health and well being (M. F. Holick). Clinical Effects of Solar Radiation. The negative effects of solar radiation: a clinical overview (F. Urbach). The effects of sunlight on the skin of Asians (J.H. Chung). Effects of solar radiation on the human immune system (M. Norval). The negative effects of solar and artificial irradiation: photoaging of the skin, its clinical appearance and underlying mechanisms (M. Wlaschek et al.). The epidemiology of solar radiation and skin cancer (B.K. Armstrong, A. Kricker). Hazards of sunlight exposure to the eye (J.E. Roberts). Photodegradation of human hair (S.B. Ruetsch et al.). Molecular Effects of Solar Radiation. UV damage to nucleic acid components (J.L. Ravanat et al.). Lipid photo-oxidative damage in biological membranes: reaction mechanisms, cytotoxic consequences and defense strategies (A. W. Girotti). Photo-oxidation of proteins and its consequences (M.J. Davies, R.J.W. Truscott). Cellular And Physiological Consquences Of Solar Radiation. Erythema: a link between UV-induced DNA damage, cell death and clinical effects? (M. Heenen). UV radiation, mutations and oncogenic pathways in skin cancer (F.R. de Gruijl, H.J. van Kranen). Modulation of gene expression by solar ultraviolet radiation (S. Basu-Modak, R.M. Tyrrell). Cytotoxicity and morphological endpoints of exposure to UV: cultured cells as a model system (E. Straface et al.). Drug-induced skin phototoxicity: lessons from the fluoroquinolones (N.K. Gibbs). Natural Defence against Solar Radiation. Pigmentation of human skin after UV (A. Young). Nucleotide excision repair of UV-radiation induced photolesions in human cells (A.A. Van Zeeland et al.). Natural defence aga


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© 2001
Elsevier Science
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About the editor

P.U. Giacomoni

Affiliations and Expertise

Clinique Laboratories, 125 Pinelawn Rd, Melville, NY 11747, USA


@from:P. Morganti - Editor-in-Chief @qu:As stated in the preface this interesting book is not "another book on sunscreens -" but a complete monograph concerning all the physical biological and dermatological aspects regarding sun protection and use of topical and systemic skin photoprotectants.
The beneficial and harmful effects of solar radiation are all well described and documented, the chemical effects of UV rays have been analyzed, investigating all the phenomena inducing immune-depression photoaging carcinogenesis.
The completeness of the topics treated and of the references reported for each chapter makes Sun protection in man a real unique textbook for chemists, bio-chemists and dermatologists involved in photobiology and photomedicine.
Pharmacy, Chemistry and Medicine students who wants to enlarge their knowledge on photobiology and sciences dealing with skin photoprotection problems should read this excellent textbook. @source:Journal of Applied Cosmetology