Stress in Health and Disease
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Stress in Health and Disease presents the principal pathways mediating the response to a stressor. It discusses the clinical background of cross-resistance and treatment with stress-hormones. It addresses the diseases of adaptation or stress diseases, diagnostic indicators, and functional changes. Some of the topics covered in the book are the concept of heterostasis; stressors and conditioning agents; morphology of frostbite; characteristics manifestations of stress; catecholamines and their derivatives; various hormones and hormone-like substances; FFA, triglycerides and lipoproteins; morphologic changes; and hypothalamo-hypophyseal system . The gastrointestinal diseases of adaptation are covered. The schizophrenia and related psychoses is discussed. The text describes the manic-depressive disease and senile psychosis. A study of the experimental cardiovascular diseases and neuropsychiatric diseases is presented. A chapter is devoted to the diseases of adaptation in animals. Another section focuses on the shift in adenohypophyseal activity and catatoxic hormones. The book can provide useful information to scientists, doctors, students, and researchers.
Table of Contents
Foreword
Purpose and Scope
Prefatory Remarks on the Style of this Book
General Structure
References
Critique and Personal Observations
Reviews
Our Earlier Stress Monographs
General
Popular
Foreign Languages
How to Use This Book
Glossary
Stress Tests
I. History and General Outline of the Stress Concept
History
Prescientific Intuitive Feelings Foreshadowing the Existence of Stress
Beginnings of a Scientific Analysis
The General Adaptation Syndrome (G.A.S.)
General Outline
Definition and Terminology of Biologic Stress
Principal Pathways Mediating the Response to a Stressor
Conditioning
Degrees of Specificity, Relationship between the G.A.S
and L.A.S
Cross Resistance and Treatment with Stressors or Stress Hormones
The Diseases of Adaptation or Stress Diseases
Syntoxic and Catatoxic Responses
The Concept of Heterostasis
Behavioral Implications
II. Stressors and Conditioning Agents
Trauma
Generalities
→ ACTH and Corticoids
→ Catecholamines (EP, NEP)
→ STH
→ Insulin
→ Sex Hormones
→ Other Hormones
→ Histamine and 5-HT
→ Enzymes
→ Other Metabolites
→ Other Targets
+ Age
+ Anesthesia
+ Temperature
+ Season
+ Diet
+ Genetics
Drugs
AMP, ADP, ATP
Alloxan
Aminoglutethimide
Amphenone
Anesthetics and Analgesics
Antiadrenergics
Antibiotics
Anticholinergics
Antihistamines
Asiaticoside
Benzol
Cannabis
Chlorpromazine
CNS Stimulants
Colchicine
Cysteamine
DDD
DDT
DNA, RNA
Dibenzyline
Diphenylhydantoin
DMSO
DOPA
Electrolytes, Water, Osmotic Pressure
Ethanol
Ethionine
α-Ethyltryptamine, α-Methyltryptamine
Formaldehyde
Glucose
6-Hydroxydopamine
Insecticides
Isethionate
MAO Inhibitors
Meprobamate
Methadone
Methamphetamine
Metrazol
Metyrapone (Metopirone)
Morphine
α-MT
Mustards
Narcotics and Other Psychotropic Drugs
Nialamide
Nicotine
Nicotinic Acid
Nitrous Oxide
PCPA
Pimozide
Poly chlorinated Biphenyls
Psychotropic Drugs
Reserpine
Ricin
Salicylates
Tranquilizers
Vitamins
Various Drugs or Drug Combinations Not Previously Mentioned
Hormones and Hormone-like Substances
Catecholamines
Corticoids
Glucagon
Gonadotropic and Gonadal Hormones
Histamine and 5-HT
Insulin
Pineal Hormones
Renin, Angiotensin
STH
Thymus Hormones
Thyroid Hormones
Vasopressin.
Diet
Generalities
→ Hormones
→ Varia
+ Temperature Variations
+ Restraint
+ Other Stressors
Physical Agents
Temperature, including Frostbite
Burns
Sound
Ultrasound, Sonic Booms
Ionizing Rays
Light Rays
Ultraviolet Rays
Vibration
Air Blasts
Compression, Decompression
Gravity
Electricity, Electroshock
Magnetism
Osmotic Pressure
Microorganisms and Their Toxins
Generalities
→ Hormones
+ Varia
Immunity
Hypoxia, Decreased Barometric Pressure including Hyperbaric Oxygenation
Generalities
→ Morphology
→ Hormones
→ Enzymes and Other Metabolites
→ Nervous Changes
→ Varia
+ Varia
Hemorrhage
Muscular Exercise
Generalities
→ Hormones
→ Enzymes and Other Metabolites
+ Varia
Restraint
Generalities
→ Hormones
→ Enzymes and Other Metabolites
→ Varia
+ Varia
Athletics
Generalities
→ Hormones
+ Varia
Neuropsychologic Stimuli
Generalities
Pain and Grief
Anxiety, Anticipation, Fear, Arousal
Public Speaking
Sleep Deprivation
Motivation
Cognition
Fighting, Anger, Hate
Sensory Deprivation, Boredom, Monotony
Pleasure
Handling and Gentling
Varia
Climate, Environment
Generalities
Pollution
Social, Cultural, Family
Crowding
Isolation
Captivity
Concentration Camps, POWs
Relocation and Travel
Urbanization
Catastrophe, Accidents
Biorhythms
Circadian
Seasonal Variations
Hibernation
Meteorologic Influences
Occupation
Aerospace
Parachute Jumping
Air Traffic Control
Navy, Marine, Submarine
Diving
Military Life, including Combat
Automobile Driving
Industry, Labor, Business, Finance
Executive Life
Medicine, Dentistry, Nursing
Law
Police Work
Shift Work
Telephone and Telegraph Operators
Various Other Occupations
Unemployment, Retirement
Physiologic States
Age
Sex (Including the Sexual Cycle)
Pregnancy and Lactation
Genetics, Race, Constitution
Generalities
Vertebrates
Mammals
Birds
Reptiles
Amphibians
Fish
Invertebrates
Plants and Microorganisms
Tumors
Combined Effect of Various Agents
Multiple Stressors (Cross-resistance and Cross-sensitization)
III. Characteristic Manifestations of Stress
Chemical Changes
Body Weight
Basal Metabolic Rate (BMR)
Other Metabolites
Morphologic Changes
Hypothalamo-hypophyseal System
Adrenals
Thyroid
Sex Organs (including Pregnancy and Lactation)
Pancreas
Pineal Gland
Thymicolymphatic and Hematopoietic Organs
Blood Cells, Blood Volume
Cardiovascular System
Gastrointestinal System
Oral (Teeth, Periodontal) Structures
Salivary Glands
Lung
Ocular Structures
Kidney
Liver
Connective Tissue, Wound Healing, Regeneration and Inflammation
Skin
Reticuloendothelial System (RES)
Tumors
Other Morphologic Changes
Functional Changes
Resistance
Nervous System
Stress Tests
Body Temperature
Cardiovascular System, including Blood Pressure, ECG
Muscular System
Blood Coagulation
Immunology
Death
Varia
IV. Diseases of Adaptation
Generalities
Shock
Gastrointestinal Diseases of Adaptation
Peptic Ulcers
Experimental Peptic Ulcers
Ulcerative Colitis
Varia
Cardiovascular Diseases (including Hypertension, Cardiac Infarcts, Periarteritis Nodosa)
Generalities
History
← Stressors in General
← Psychogenic Stressors
← Conditioning
Diagnostic Indicators and Other Changes Characteristic of Stress-induced Cardiovascular Disease
Experimental Cardiovascular Diseases
Neuropsychiatric Diseases
Generalities
Psychosomatic
Neuroses
Schizophrenia and Related Psychoses
Manic-depressive Disease
Toxicomanias (including Alcoholism)
Senile Psychosis
Other Neuropsychiatric and Psychosomatic Diseases
Experimental Neuroses (including Toxicomanias)
Other Diseases of Adaptation
Diabetes Mellitus
Hypoglycemia and Hyperinsulinism
Thyroid Diseases
Cushing's Disease
Immunity, Allergy and Infections
Tumors
Pancreatitis
Renal Diseases
Gynecologic Diseases
Oral, Dental Diseases
Ocular Diseases
Skin Diseases
Gastrointestinal Diseases
Nutritional Diseases (including Kwashiorkor)
Ménière's Disease
Varia
Pluricausal Diseases
Diseases of Adaptation in Animals
Generalities
Shipping Fever
Varia
V. Treatment
Generalities
Rest and Leisure
Psychotherapy in General
Handling and Gentling
Transcendental Meditation (TM) and Related Techniques
Zen and Yoga
Hypnosis
Psychoanalysis
Acupuncture and Moxibustion
Chiropractic
Osteopathy
Various Stressors (Mental and Physical)
Diet
Hormones and Related Substances
Vitamins
Psychotropic Drugs in General
Autonomic Blocking Agents
Ginseng, Eleutherococcus
Ethanol
Other Drugs
Smoking
VI. Theories
General Mechanisms
Nervous Mechanisms
Dictionary
Anatomic Drawings and Explanatory Tables
General Discussion of CRF and the Results of Experiments
Deafferentation of the Hypophysiotrophic Area
Abstracts of Literature on Various Nervous Mechanisms
Hormonal Mechanisms
Anterior Lobe of the Hypophysis
Middle {Intermediate) Lobe of the Hypophysis, MTH (MSH)
Posterior (Neural) Lobe of the Hypophysis
Adrenals
The Shift in Adenohypophyseal Activity
Syntoxic and Catatoxic Hormones
Other Hormones and Hormone-like Substances
Various Mechanisms
The First Mediator
General Adaptation Syndrome (G.A.S.) vs Local Adaptation Syndrome (L.A.S.)
Conditioning
The Three Phases of the G.A.S., Adaptation Energy, Aging
Stress and Fatigue
Various Other Theories
VII. Various Other Related Topics
Legal Implications
Philosophic Implications
Institutes, Laboratories, and Societies Primarily or Exclusively Devoted to Stress Research
Epilogue
Author Index
Subject Index
Product details
- No. of pages: 1300
- Language: English
- Copyright: © Butterworth-Heinemann 1976
- Published: January 1, 1976
- Imprint: Butterworth-Heinemann
- eBook ISBN: 9781483192215
About the Author
Hans Selye
Latest reviews
(Total rating for all reviews)
Dr D. Tue Apr 07 2020
the General adaptation syndrome by Hans Selye
the book is a compilation of the experiences and inquiries of a medical mind of Dr Hans Selye since he was a medical student. He has thought on the patho - physiology of a disease in a totally different way , considering the role of learning and behaviour in the genesis of a disease , its course and outcome.