Spin Labeling - 1st Edition - ISBN: 9780120923526, 9781483216416

Spin Labeling

1st Edition

Theory and Applications

Editors: Lawrence J. Berliner
eBook ISBN: 9781483216416
Imprint: Academic Press
Published Date: 28th April 1979
Page Count: 374
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Spin Labeling II: Theory and Applications covers spin-labeled biopolymers and its importance to both macromolecular modeling as well as some industrially based problems. The book discusses the methods of saturation-transfer spectroscopy; the spin-probe-spin-label method; and new aspects of nitroxide chemistry. The text also describes the spin-labeled synthetic polymers; the impact that the technique of spin labeling has on pharmacology and on biomedicine; as well as the applications of spin labeling to nucleic acids. Chemists, pharmacologists, biochemists, and people working in the field of biological magnetic resonance will find the book invaluable.

Table of Contents

List of Contributors Preface

  1. Saturation-Transfer Spectroscopy I. Introduction II. Physics of the Very Slow Tumbling Domain III. Experimental Methods IV. Theory V. Computational Efficiency VI. Applications of Saturation-Transfer Electron Paramagnetic Resonance VII. Anisotropic or Special Motions References
  2. The Spin-Probe-Spin-Label Method I. Introduction II. Theory III. Survey of Chemical and Magnetic Properties of Paramagnetic Metal-Ion Probes IV. Applications of the Method References
  3. New Aspects of Nitroxide Chemistry I. Introduction II. Structural Features That Make a Nitroxide Stable III. Characterization of New Nitroxide Spin Labels and Nitroxide Spectra IV. Synthesis of New Stable Nitroxide Spin Labels V. Chemical Reactions Involving the Nitroxide Grouping VI. Chemical Reactions Not Involving the Nitroxide Grouping VII. Dinitroxide Spin Labels VIII. Experimental Procedures for the Synthesis of Selected Proxyl and Imidazolidine-Derived Nitroxide Spin Labels References
  4. Spin-Labeled Synthetic Polymers I. Introduction II. Sample Preparation III. Analysis in Polymeric Materials IV. Motion in Bulk Polymers V. Effect of Diluents VI. Conformation of Polymers Adsorbed at Solid-Liquid Interfaces VII. Conclusion References
  5. Spin Labeling in Pharmacology I. Introduction II. Drug Absorption, Distribution, and Excretion III. Drug Metabolism IV. Pharmacological Effects of Drugs V. Future of Spin-Labeling Studies in Pharmacology References
  6. Spin Labeling in Biomedicine I. Introduction II. Spin Assay III. Spin Immunoassay IV. Spin-Membrane Immunoassay V. Spin Labeling in Carcinogenesis VI. Spin Trapping VII. In Vivo Electron Spin Resonance References
  7. Applications of Spin Labeling to Nucleic A


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© Academic Press 1979
Academic Press
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About the Editor

Lawrence J. Berliner

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