Special Topics and General Characteristics

Special Topics and General Characteristics

Diseases Caused by Protista

1st Edition - January 1, 1968

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  • Editors: David Weinman, Miodrag Ristic
  • eBook ISBN: 9781483270661

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Infectious Blood Diseases of Man and Animals: Diseases Caused by Protista, Volume I: Special Topics and General Characteristics focuses on the critical analysis of metabolic, immuno-pathologic, taxonomic, ultrastructural, locomotor, ecologic, zoonotic, and other features of the protistan blood diseases. The selection first offers information on ecology and host-parasite relationship; basis of host cell-parasite specificity; and abrogation of immunological tolerance as a model for autoimmunity. Topics include interactions in disease transmission, types of host-parasite relationship, and experimental abrogation of tolerance. The text then takes a look at autoimmune response and pathogenesis of blood parasite disease and blood parasite antigens and antibodies. The publication examines the zoonotic potential of blood parasites, including diseases caused by bacteria and spirochetes and trypanosomiasis. The text then focuses on the cultivation and nutritional requirements and biological leads to chemotherapy of blood Protista. Discussions focus on organisms developing within the blood cells; energy metabolism and chemotherapeutic targets; and protozoa developing primarily in the plasma. The book is a valuable reference for readers interested in the diseases caused by Protista.

Table of Contents

  • List of Contributors



    Contents of Volume II

    Part I: Special Topics

    1. Ecology and Host-Parasite Relationship

    I. Types of Host-Parasite Relations

    II. Relation of Vertebrate Host Group to Parasite Group

    III. Patterns of Host Response to Blood Parasites

    IV. Relation of Parasite Group to Vector Group

    V. Interactions in Disease Transmission

    VI. Landscape Epidemiology


    2. Basis of Host Cell-Parasite Specificity

    I. Introduction

    II. Factors Affecting Host Cell-Parasite Specificity in the Vertebrate Host

    III. Susceptibility of Arthropod Vectors to Protozoan Parasites

    IV. Conclusion


    3. Abrogation of Immunological Tolerance as a Model for Autoimmunity

    I. Introduction

    II. The Immunological Recognition System

    III. Experimental Abrogation of Tolerance

    IV. Conclusions


    4. Autoimmune Response and Pathogenesis of Blood Parasite Diseases

    I. The Immunological Basis of Anemia in Erythrocytic Infections

    II. Concepts of Autoimmune Response

    III. Immunopathology

    IV. Protection Resulting from the Autoimmune Response


    5. Blood Parasite Antigens and Antibodies

    I. Plasmodia

    II. Trypanosomes

    III. Theileria

    IV. Babesia

    V. Anaplasma

    VI. Eperythrozoon and Haemobartonella


    6. Zoonotic Potential of Blood Parasites

    I. Introduction

    II. Definitions

    III. Diseases Caused by Bacteria and Spirochetes

    IV. Trypanosomiasis

    V. Malaria

    VI. Babesiosis


    Part II: General Characteristics of the Blood Protists

    7. Definition and Classification

    I. The Concept of Protista

    II. Problems of Protistan Taxonomy

    III. Rules of Nomenclature

    IV. Definition of Blood Protists

    V. Skeletal Scheme of Classification

    VI. Annotated Bibliography

    8. Cultivation and Nutritional Requirements

    I. Introduction

    II. Protozoa Developing Primarily in the Plasma: The Hemoflagellates

    III. Organisms Developing within the Blood Cells


    9. Some Biological Leads to Chemotherapy of Blood Protista, Especially Trypanosomatidae

    I. Introduction: Need for Better Screening Methods for Antiprotozoal Agents

    II. Pitfalls in Screening for Antiprotozoal Agents

    III. The Antimetabolite Approach: Ways to Identify New Metabolites as Potential Chemotherapeutic Targets

    IV. Seductions of Molecular Biology; DNA Binding

    V. Energy Metabolism and Chemotherapeutic Targets

    VI. Prospects


    10. The Fine Structure

    I. Introduction

    II. Protozoa Invading Blood Cells

    III. Protozoa Not Invading Blood Cells (Trypanosomes)

    IV. Conclusion and General Remarks


    11. Development and Reproduction (Vertebrate and Arthropod Host)

    I. Introduction

    II. The Trypanosomatidae

    III. The Plasmodiidae


    12. Preservation and Storage in Vitro

    I. Preservation by Freezing

    II. Preservation by Freeze-Drying

    III. Results Obtained


    13. Investigational Problems and the Mechanisms of Inheritance in Blood Protozoa

    I. Introduction

    II. Cytological Analysis of Genetic Systems

    III. Genetic Markers

    IV. Developmental Genetics

    V. Population Dynamics


    14. Locomotion of Blood Protists

    I. Hydrodynamic and Thermodynamic Problems

    II. Locomotion by Active Body Flections

    III. Locomotion of Flagellated Protozoa

    IV. Summary


    Author Index

    Subject Index

Product details

  • No. of pages: 508
  • Language: English
  • Copyright: © Academic Press 1968
  • Published: January 1, 1968
  • Imprint: Academic Press
  • eBook ISBN: 9781483270661

About the Editors

David Weinman

Miodrag Ristic

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