Somatosensory Feedback for Neuroprosthetics

Somatosensory Feedback for Neuroprosthetics

1st Edition - July 19, 2021

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  • Editor: Burak Guclu
  • eBook ISBN: 9780128230008
  • Paperback ISBN: 9780128228289

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Although somatosensory system works in tandem with the motor system in biology, the majority of the prosthetics research and commercial efforts had focused on accommodating movement deficits. With the development of neuroprostheses in the last 15 years, it has become evident that somatosensory input (mainly as touch and proprioception) is essential for motor control, manipulating objects, and embodiment, in addition to its primary role for sensory perception.Somatosensory Feedback for Neuroprosthetics covers all relevant aspects to facilitate learning and doing research and development in the field.To understand the properties of the body to create viable solutions, this book starts with chapters reviewing the basic anatomy, physiology, and psychophysics of the somatosensory system, sensorimotor control, and instrumentation. Some sections are dedicated to invasive (peripheral and central, mainly cortical) and noninvasive (vibrotactile, electrotactile, etc.) approaches. Final chapters cover future technologies such as novel sensors and electrodes, safety, and clinical testing, and help to make up future prospects for this field with an emphasis on development and end use. With contributions from renowned experts, the contents include their recent findings and technical details necessary to understand those findings.

Key Features

  • Provides a concise review of the somatosensory system and latest advances in the use of somatosensory feedback for neuroprosthetics
  • Analyzes many approaches to somatosensory feedback
  • Provides the most detailed work on somatosensory neuroprostheses, their development, and applications in real life work


Graduate students, post-doctoral fellows, professors, R&D engineers working on the neurobiology of somatosensory system, neurophysiology, psychophysics, biomedical signal processing, computational science, bio-robotics, MEMS design, bioelectronics, nanotechnology, mechanical design, prosthetics, medical specialties (especially neurosurgery, neurology, physical medicine and rehabilitation)

Table of Contents

  • Part I Background and fundamentals
    1. Introduction to somatosensory neuroprostheses
    Burak Guclu
    2. Proprioception: a sense to facilitate action
    Kyle P. Blum, Christopher Versteeg, Joseph Sombeck, Raeed H. Chowdhury and Lee E. Miller
    3. Electrodes and instrumentation for neurostimulation
    Daniel R. Merrill
    4. Stimulus interaction in transcutaneous electrical stimulation
    Sigrid Dupan, Leen Jabban, Benjamin W. Metcalfe and Kianoush Nazarpour

    Part II Non-invasive methods for somatosensory feedback and modulation
    5. Supplementary feedback for upper-limb prostheses using noninvasive stimulation: methods, encoding, estimation-prediction processes, and assessment
    Jakob Dideriksen and Strahinja Dosen
    6. Noninvasive augmented sensory feedback in poststroke hand rehabilitation approaches
    Leonardo Cappello, Rebecca Baldi, Leonard Frederik Engels and Christian Cipriani
    7. Targeted reinnervation for somatosensory feedback
    Jacqueline S. Hebert and Paul D. Marasco
    8. Transcranial electrical stimulation for neuromodulation of somatosensory processing
    Sacit Karamursel and Ezgi Tuna Erdogan

    Part III Peripheral nerve implants for somatosensory feedback
    9. Connecting residual nervous system and prosthetic legs for sensorimotor and cognitive rehabilitation
    Giacomo Valle, Greta Preatoni and Stanisa Raspopovic
    10. Biomimetic bidirectional hand neuroprostheses for restoring somatosensory and motor functions
    Francesco Iberite, Vincent Mendez, Alberto Mazzoni, Solaiman Shokur and Silvestro Micera

    Part IV Cortical implants for somatosensory feedback
    11. Restoring the sense of touch with electrical stimulation of the nerve and brain
    Thierri Callier and Sliman J. Bensmaia
    12. Intracortical microstimulation for tactile feedback in awake behaving rats
    Ismail Devecioglu, Sevgi Ozturk and Burak Guclu
    13. Cortical stimulation for somatosensory feedback: translation from nonhuman primates to clinical applications
    Marion Badi, Simon Borgognon, Joseph E. O’Doherty and Solaiman Shokur
    14. Touch restoration through electrical cortical stimulation in humans
    David J. Caldwell, Jeneva A. Cronin, Lila H. Levinson and Rajesh P.N. Rao
    15. Design of intracortical microstimulation patterns to control the location, intensity, and quality of evoked sensations in human and animal models
    David A. Bjanes and Chet T. Moritz

    Part V Future technologies
    16. Neural electrodes for long-term tissue interfaces
    Jaume del Valle, Bruno Rodriguez-Meana and Xavier Navarro
    17. Challenges in neural interface electronics: miniaturization and wireless operation
    Senol Mutlu
    18. Somatosensation in soft and anthropomorphic prosthetic hands and legs
    Oguzhan Kirtas and Evren Samur
    19. Prospect of data science and artificial intelligence for patient-specific neuroprostheses
    Buse Buz Yalug, Dilek Betul Arslan and Esin Ozturk-Isik
    20. Modern approaches of signal processing for bidirectional neural interfaces
    Andrea Cimolato, Natalija Katic and Stanisa Raspopovic
    21. Safety and regulatory issues for clinical testing
    Daniel R. Merrill

Product details

  • No. of pages: 716
  • Language: English
  • Copyright: © Academic Press 2021
  • Published: July 19, 2021
  • Imprint: Academic Press
  • eBook ISBN: 9780128230008
  • Paperback ISBN: 9780128228289

About the Editor

Burak Guclu

Prof. Burak Güçlü has an engineering background (BS in 1997: Control and Computer Engineering, Istanbul Technical University; MS in 1999: Bioengineering, Syracuse University), completed PhD (2003, Syracuse University) and postdoctoral work (University of Rochester) in neuroscience mostly with specialization on the somatosensory system. He has over 20 years of experience in theoretical and experimental research involving the sense of touch in animals, humans, and for engineering applications such as neuroprosthetics and tactile sensors/displays. He has 51 articles published in refereed journals and over 120 publications in conferences. He has worked in grant projects funded by NIH, TÜBİTAK, European Union, and university agencies; is currently part of an EU consortium for the use of graphene electrodes in neuroprosthetics, and has established Tactile Research Laboratory and the animal facility (Vivarium) at Boğaziçi University. He has taught courses on sensory systems, computational neuroscience, biophysics, and biomedical instrumentation, and gave numerous lectures and provided media coverage on somatosensory feedback in neuroprosthetics.

Affiliations and Expertise

Professor, Institute of Biomedical Engineering, Bogazici University, İstanbul, Turkey

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