Sleep, Epilepsies, and Cognitive Impairment discusses the brain mechanisms behind epilepsy by applying the results of contemporary neuroimaging and signal analysis. This book helps the reader view epilepsy from new perspectives, emphasizing the role of epilepsy-activation by NREM sleep in the cognitive impairment of certain major epilepsies. The authors describe the impact of activations of interictal and ictal events during NREM sleep, putting special emphasis on the cognitive impairment consequences. Epileptic disorders are approached by the network concept, especially in relation to the derailment of certain physiological systems transformed to epileptic networks.
The book looks at epilepsy with a fresh eye that is armed by contemporary neuroscience, trying to enlighten epilepsy syndromes in new aspects. Its aim is to interpret the major epileptic syndromes as system epilepsies involving brain physiological networks. The authors endeavor to reveal the links between brain plasticity, epilepsy and NREM sleep.
Neuroscientists, clinical epileptologists and neurologists interested in brain processes underlying brain plasticity, sleep and epilepsy will find this book thought provoking.
- Provides contemporary knowledge about the neurophysiological and functional anatomical background of major epilepsies
- Treats major epilepsies as system epileptic networks
- Reveals the interrelationship of sleep and epilepsy from new viewpoints
Researchers and clinicians focused on neurology, neuroscience, sleep, and neurophysiology
- General considerations
2. The network concept of epilepsy
3. Activation of epilepsy in sleep
4. Absence Epilepsy as system epilepsy of the sleep promoting function
5. Nocturnal Frontal Lobe Epilepsy as epilepsy of the arousal system from sleep
6. Juvenile Idiopathic Myoclonic Epilepsy as the common disorder of the cortoco-thalamic and motpr system
7. Reading Epilepsy as epilepsy of the speech function
8. Medial Temporal Lobe Epilepsy as epilepsy of the limbic system of declarative memory processing
9. Peri-sylvian epileptic network: childhood idiopathic benign regional hyperexcitability (HIEC) conditions (Rolandic Epilepsy, Panayitopoulos syndrome)- Common features in HIEC conditions
10. Malignant transformation of HIEC conditions to Electrical status Epilepticus in Sleep in global (ESES) and regional (Landai-Kleffner Syndrome ) forms.
11. The spectrum disorders of the peri-sylvian epileptic network
12. Epileptic Encephalopathies (West Syndrome, Lennox-Gastaut Syndrome – Common features of Epileptic Encephalopathies
13. The common mechanisms in childhood epileptic encephalopathies with immense sleep activation and cortical pathological HFO activity
14. The outstanding role of interictal dicharges (IEDs) in epileptic encephalopathies and in cognitive impairment of epilepsy
15. The role of slow wave sleep in the development and progression in system epilepsies
16. Epilepsy types in an other way
- No. of pages:
- © Academic Press 2018
- 15th January 2018
- Academic Press
- Paperback ISBN:
Dr. Halász is an acknowledged epileptologist, and sleep researcher. He is an emeritus professor of Neurology at the National Institute of Clinical Neuroscience, Budapest. He is the author of more than 200 international publication, mainly on epilepsy and sleep, and several books. He is also a life member of the Hungarian Epilepsy League leading board.
Emeritus Professor of Neurology, National Institute of Clinical Neuroscience, Budapest, Hungary
Dr. Szűcs is a neurologist and psychiatrist, and chief physician in the National Institute of Clinical Neuroscience. She is a sleep expert and neurophysiologist, as well as an author of 50 international publications and 2 books
Chief Physician, National Institute of Clinical Neuroscience, Budapest, Hungary