Sleep Disorders Part I, Volume 98

1st Edition

Editors: Pasquale Montagna Sudhansu Chokroverty
Hardcover ISBN: 9780444520067
eBook ISBN: 9780444534811
Imprint: Elsevier
Published Date: 16th December 2010
Page Count: 720
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Table of Contents

Foreword Preface Acknowledgments List of contributors Section 1 History of sleep medicine

1. History of sleep medicine

Section 2 Basic science and methods

2. Normal sleep-recording and scoring techniques 3. Assessment of daytime sleepiness 4. Actigraphic monitoring of sleep and circadian rhythms 5. Video recordings and video polysomnography 6. Functional neuroimaging in sleep, sleep deprivation, and sleep disorders

Section 3 Basic mechanisms of sleep

7. The phylogeny of sleep 8. Ontogeny of EEG sleep from neonatal through infancy periods 9. Neurobiology of waking and sleeping 10. Neurobiology of REM sleep 11. Neurochemistry of sleep: an overview of animal experimental work 12. Molecular neurobiology of sleep 13. Manifestations and functional implications of sleep homeostasis 14. Thermoregulation in wakefulness and sleep in humans 15. Cytokines in immune function and sleep regulation 16. Endocrine and metabolic changes during sleep 17. Sleep, memory, and molecular neurobiology

Section 4 Clinical aspects of sleep disorders

18. Epidemiology of sleep disorders 19. Cardiovascular and cerebrovascular physiology in sleep 20. Cardiovascular diseases and sleep apnea 21. Alterations in gastrointestinal functioning during sleep 22. Sleep and genitourinary systems: physiology and disorders 23. Sleep enuresis 24. Respiratory physiology in sleep and wakefulness 25. Obstructive sleep apnea: diagnosis, risk factors, and pathophysiology 26. Upper-airway resistance syndrome 27. Central sleep apnea 28. Positive-pressure treatment of obstructive sleep apnea syndrome 29. Medical and surgical treatment of obstructive sleep apnea syndrome, including dental appliances 30. Noninvasive positive ventilation in the treatment of sleep-related breathing disorders 31. Sleep and pulmonary diseases 32. Sleep-associated respiratory dis


Sleep Disorders Part 1 offers a glimpse of developments that focus on diagnostic techniques in the field of neurobiology of sleep. This part discusses the models of the rapid eye movement (REM) sleep mechanism; issues regarding sleep states, stages, and memory consolidation; and advances in the understanding of the sleep-wake genes, gene products, the circadian clock, and the role of sleep duration.
This book explains noninvasive neuroimaging studies, particularly positron emission tomographic and single photon emission computed tomographic scans. It further discusses advances in clinical science, including concepts about neurobiology of sleep, narcolepsy-cataplexy, therapy, and laboratory techniques. The significant advances in therapy have led to the addition of new drugs for the treatment of different sleeping disorders, as described in this book. Sleep is essential to humans. Awareness of its true importance leads to the development and acceptance of sleep medicines in the market.

Key Features

  • Clinical data on groundbreaking advancements in the understanding of basic sleep science
    Invaluable information on new therapies and drug protocols for sleep disorders
    A state-of-the-art reference that includes the role of genetics in sleep medicine


Neuroscience research workers


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© Elsevier 2011
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About the Editors

Pasquale Montagna Editor

Affiliations and Expertise

Department of Neurological Sciences, University of Bologna, Italy

Sudhansu Chokroverty Editor

Affiliations and Expertise

Professor and Co-Chair of Neurology, Program Director, Clinical Neurophysiology and Sleep Medicine, New Jersey Neuroscience Institute at JFK Medical Center and Seton Hall University, Edison, New Jersey; Clinical Professor of Neurology, Robert Wood Johnson Medical School, New Brunswick, New Jersey