Single-Cell Omics

Single-Cell Omics: Technological Advances and Applications provides the latest technological developments and applications of single-cell technologies in the field of biomedicine. In the current era of precision medicine, the single-cell omics technology is highly promising due to its potential in diagnosis, prognosis and therapeutics. Sections in the book cover single-cell omics research and applications, diverse technologies applied in the topic, such as pangenomics, metabolomics, and multi-omics of single cells, data analysis, and several applications of single-cell omics within the biomedical field, for example in cancer, metabolic and neuro diseases, immunology, pharmacogenomics, personalized medicine and reproductive health.

This book is a valuable source for bioinformaticians, molecular diagnostic researchers, clinicians and members of the biomedical field who are interested in understanding more about single-cell omics and its potential for research and diagnosis.

• Covers not only the technological aspects, but also the diverse applications of single cell omics in the biomedical field
• Summarizes the latest progress in single cell omics and discusses potential future developments for research and diagnosis
• Written by experts across the world, bringing different points-of-view and case studies to give a comprehensive overview on the topic

Bioinformaticians, molecular diagnostic researchers, clinicians, geneticists

Section I Overview of Single Cell Omics
CHAPTER 1 Single Cell Omics: An Overview
CHAPTER 2 Recent Progress in Single-Cell Sequencing
CHAPTER 3 Cellular Heterogeneity and Single-Cell Omics
CHAPTER 4 Single-Cell Omics: Cellular Functions
CHAPTER 5 Single-Cell Omics: Deciphering Tumor Clonal Architecture

Section II Omics Technologies in Single Cell
CHAPTER 6 An Overview of Single-Cell Isolation Techniques
CHAPTER 7 Microfluidic Techniques for Single-Cell Culture
CHAPTER 8 Single-Cell Omics in Noninvasive Diagnosis and Testing—Surface-Enhanced Raman Spectroscopy-Based Approach
CHAPTER 9 Single-Cell Genomics: Technology and Applications
CHAPTER 10 Single-Cell Metagenomics
CHAPTER 11 Single-Cell Epigenomics: Technology and Applications
CHAPTER 12 Single-Cell Transcriptomics: Technology and Applications
CHAPTER 13 Single-Cell Transcriptomics of Skeletal Muscle: Technology and Applications
CHAPTER 14 Single-Cell Proteomics: Technology and Applications
CHAPTER 15 Single-Cell Metabolomics: Technology and Applications
CHAPTER 16 Single-Cell Phenomics in Budding Yeast: Technologies and Applications
CHAPTER 17 Robotics in Single Cell Omics
CHAPTER 18 Single-Cell Editing: The CRISPR/Cas9 and Applications
CHAPTER 19 Data Analysis in Single-Cell RNA-Seq
CHAPTER 20 Systems-Level Understanding of Single-Cell Omics