Sialic Acids and Sialoglycoconjugates in the Biology of Life, Health and Disease

Sialic Acids and Sialoglycoconjugates in the Biology of Life, Health and Disease

1st Edition - January 8, 2020

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  • Author: Shyamasree Ghosh
  • Paperback ISBN: 9780128161265
  • eBook ISBN: 9780128161272

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Sialic Acids and Sialoglycoconjugates in the Biology of Life, Health and Disease enables the reader to understand the role of sialylation as a post translational modification. The book provides insights on the latest knowledge in the field of sialoglycobiology. Sialic acids as terminal residues of oligosaccharide chains play crucial roles in several cellular recognition events. Synthesized post translationally, they play an important role in recognition, signaling, immunological response and cell-cell interaction. Improper sialylations have been associated with several diseases including cancer. In the post genomics and proteomics era, sialoglybiology has become more and more important in deciphering health and disease conditions.

Key Features

  • Discusses the sialic acids and their role in different diseases (other than cancer)
  • Provides an understanding of sialylations as post translational modifications (PTM)
  • Demonstrates the impact sialylation has on infectious diseases, the autoimmune system and health
  • Gives insights on the importance of sialic acid biology through animal models


Masters, Graduate Students of life sciences, microbiology, immunology, biochemistry, biology, glycobiology, medicine; doctors, medical professionals, researchers

Table of Contents

  • 1. Sialic Acid and Biology of Life: An Introduction
    2. Sialoglycans and Genetically Engineered Plants
    3. Sialic Acid, Sialoglycans, Sialylation: A Study in Insects
    4. Sialoglycoconjugates and Human Physiology
    5. Pathogens, infectious disease biology and Sialic acid
    6. Sialic acids in autoimmune disorders
    7. Lysosomal Storage Disorders: Disorders Related to Glycans and Sialic Acid
    8. Sialic Acids and its Conjugates in Cancer
    9. Sialic Acids and its Conjugates in Endocrinal Disorders
    10. Sialic Acids and Xenotransplantation
    11. Nanotechnology and Sialic Acid Biology

Product details

  • No. of pages: 362
  • Language: English
  • Copyright: © Academic Press 2020
  • Published: January 8, 2020
  • Imprint: Academic Press
  • Paperback ISBN: 9780128161265
  • eBook ISBN: 9780128161272

About the Author

Shyamasree Ghosh

Dr. Shyamasree Ghosh (MSc, PhD, PGDHE, PGDBI) has worked and published extensively in glycobiology, biology of sialic acids, immunology, stem cells, nanotechnology and computational biology and is currently working as the Scientific Officer, since 2009 in the School of Biological Sciences, National Institute of Science Education and Research (NISER), Bhubaneswar, under Department of Atomic Energy, Govt of India currently located in Jatni, Orissa. ty. She has authored several publications that include books and encyclopedia chapters in reputed journals and books. Research that tries to decode the complexity of life with hopes for a better living forms her research interest.

Affiliations and Expertise

School of Biological Sciences, NISER, Bhubaneswar, Govt of India, Dept of Atomic Energy (DAE), Jatni Campus, PO- Bhimpur-adanpur, Via-Jatni, District- Khurda, India

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