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Sex and Gender Differences in Alzheimer’s Disease: The Women's Brain Project offers, for the first time, a critical overview of the evidence documenting sex and gender differences in AD neurobiology, biomarkers, clinical presentation, treatment, clinical trials and their outcomes and impact on caregivers. This knowledge is crucial for clinical development, digital health solutions, and as social and psychological support to AD families.
- Presents comprehensive and critical reviews of sex differences in Alzheimer’s disease
- Combines the knowledge and points-of-view of neuroscientists, medical doctors, psychologists and AI experts for a 360 degree view on the topic and its possible implications
- Edited by the Women’s Brain Project, the leading NGO in the field of sex differences in neuroscience
Neurologists, neuroscientists, psychiatrists, psychologists, nurses, advanced practice practitioners and medical ethicists
Introduction Part 1 Sex differences in fundamental neurobiological processes that are relevant to Alzheimer’s disease
1. Sex differences in Alzheimer’s disease animal model
2. Sex and sex hormone differences in hippocampal neurogenesis and their relevance to Alzheimer’s disease
3. Sex differences in microglia as a risk factor for Alzheimer’s disease
Introduction Part 2 Sex and gender differences in clinical aspects of Alzheimer’s disease
4. Sex differences in CSF biomarkers of Alzheimer’s disease
5. Sex differences in neuroimaging biomarkers in healthy subjects and dementia
6. Sex differences in neuropsychological symptoms for clinical diagnosis of Alzheimer’s disease
7. Sex differences in psychiatric disorders and their implication for dementia
8. Sleep disorders and dementia
9. Hormones and dementia
10. Sex and gender differences in genetic and lifestyle risk and protective factors for dementia
11. Sex and gender considerations in clinical trials for Alzheimer’s disease: Current state and recommendations
Introduction Part 3 Gender differences in the socio-economic factors linked to Alzheimer’s disease
12. Gender and socioeconomic differences in modifiable risk factors for Alzheimer’s disease and other types of dementia throughout the life course
13. Living with dementia and caregiving: Psychosocial considerations through the gender lens
14. Sex and gender differences in caregiving patterns and caregivers’ needs
15. Gender barriers to communication in Alzheimer’s disease
16. Women and dementia policy: Redressing imbalance through gender transformative policies
- No. of pages:
- © Academic Press 2021
- 1st July 2021
- Academic Press
- Hardcover ISBN:
Dr. Maria Teresa Ferretti is a neuroscientist and neuroimmunologist with expertise in Alzheimer’s disease and gender medicine. After graduating in Chemistry and Pharmaceutical Technologies from the University of Cagliari (Italy), Dr Ferretti started a career as a researcher in the field of neurodegeneration, working in England (for the company Glaxo Smith and Kline), Canada (where she earned a PhD in Pharmacology and Therapy from McGill University of Montreal in 2011) and Switzerland (where she was Group Leader at University of Zurich). She has published numerous scientific papers in prestigious journals including Nature, Science and PNAS; passionate about scientific communication and outreach, she was a TED-x speaker in 2019. Currently, she is the Chief Scientific Officer and co-Founder of the Women’s Brain Project; in addition, she is an external lecturer at the Medical University of Vienna, Austria.
Co-founder and Chief Scientific Officer, Women’s Brain Project, Switzerland
Dr. Annemarie Schumacher Dimech serves as President of the Women’s Brain Project, and is also one of the organization’s co-founders. She heads the new Certificate of Advanced Studies in Palliative Care and the further education programme in Healthcare and Medical Leadership at the University of Lucerne. She graduated in psychology from the University of Malta and further to receiving a Chevening Scholarship, completed an MSc in Health Psychology from the University of Surrey (UK). In 2010, she obtained her PhD at the University of Bern. Today, she is employed at the University of Lucerne where she developed and is heading its programme of further education in Palliative Care and works in the development of further education programmes in healthcare and medicine. Her fascination with the interaction between body and mind motivates her to study physical and environmental factors affecting mental health. Sex and gender differences in various factors, including socioeconomic and psychological factors, affecting brain and mental health was her motivation to join forces with Antonella Santuccione Chadha, Maria Teresa Ferretti, and Gautam Maitra to found the Women’s Brain Project. This approach forms the basis of her work with the Women’s Brain Project, where she contributes to educational and scientific events as well as various projects including publications, research, and other scientific events."
Co-founder and President, Women’s Brain Project, Switzerland Program Manager, Palliative Care, University of Lucerne, Lucerne, Switzerland
Dr. Antonella Santuccione Chadha is a medical doctor with expertise in clinical pathology, neuroscience and psychiatric disorders. She is head of stakeholder engagement for Alzheimer’s disease at Biogen. She is co-founder and CEO of the non-profit organization “Women’s Brain Project” which is addressing the influence of sex and gender on mental and brain diseases. She is the Vice-president of Euresearch. As a medical doctor, Antonella has decades of experience in preclinical research, patient treatment, clinical development, medical affairs and setting up the international regulatory framework for Alzheimer’s disease. Always focused on solving the puzzles related to Alzheimer’s and other psychiatric diseases, she has worked with Swissmedic, the Bill and Melinda Gates Foundation, several European universities, the EU Commission Directorate for Health and Food Safety, the World Health Organization, the CEOi and several Alzheimer’s’ disease Organizations. Since 2018 she is listed among the top 100 Women in Business in Switzerland and in 2019 she has been elected Woman of the Year in Switzerland by the Magazine "Women in Business". In 2020, she received the World Sustainability Award for her involvement in advancing Precision Medicine. She also received the award “Premio Medicina Italia” for her contribution to the management of the pandemic. Dr. Santuccione Chadha is keenly interested in removing bias when developing solutions for mental and neurological diseases to achieve precision medicines.
CEO pro Bono Women’s Brain Project Head of Stakeholder Engagement for Alzheimer’s Disease Biogen International. Vice-President at Euresearch
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