Self-assembling Biomaterials - 1st Edition - ISBN: 9780081020159

Self-assembling Biomaterials

1st Edition

Molecular Design, Characterization and Application in Biology and Medicine

Editors: Helena S. Azevedo Riccardo M. P. da Silva
Hardcover ISBN: 9780081020159
Imprint: Woodhead Publishing
Published Date: 1st April 2018
Page Count: 810
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Self-assembling Biomaterials: Molecular Design, Characterization and Application in Biology and Medicine provides comprehensive information on an emerging area of biomaterials science. It presents conceptual designs and advanced characterization tools, presenting the features of self-assembly. The book begins by separately addressing the theoretical and practical aspects of self-assembly. Further chapters look at the use of dynamic self-assembly (out of equilibrium), an emerging and exciting area that could revolutionize the field of self-assembling biomaterials. In addition, characterization techniques are discussed, as is the dissemination of self-assembling biomaterials in specific applications.

Written by researchers working in self-assembling biomaterials, this approach guarantees that even the more theoretical aspects of self-assembly are described according to the specific needs of the biomaterials scientific community.

Key Features

  • Explores both theoretical and practical aspects of self-assembly in biomaterials
  • Includes a dedicated section on characterization techniques, specific for self-assembling biomaterials
  • Examines the use of dynamic self-assembling biomaterials


Materials scientists, biomedical engineers, chemists working in the field of soft-matter, biomaterials and stem cells for tissue engineering

Table of Contents

Part 1 - Molecular building blocks for self-assembly of biomaterials
1. Nucleic acids
2. Peptides
3. Proteins
4. Saccharides
5. Synthetic polymers
6. Lipids
7. Hybrids
8. Synthetic supramolecular systems
9. Host-guest interactions

Part 2 - Mechanisms of self-assembly: controlling driving forces and boundaries for self-assembly across scales
10. Discrete (soluble/particulate) vs continuous (bulk materials/ hydrogels)
11. Shear/field-induced self-assembly
12. Self-assembly in confined environments
13. Interfacial self-assembly
14. Bulk/solution
15. Orthogonal self-assembly

Part 3 - Unique properties of self-assembling biomaterials: blurring the frontiers between biomaterials and biology
16. Nanostructuring
17. Reversibility
18. Easy incorporation of chemical functionality with great spatial control
19. Adaptability
20. Dynamic/Dissipative self-assembly (out of equilibrium) applications

Part 4 - Nanoscale characterization of self-assembling biomaterials
21. Nanoscale Imaging
22. Nanoscale structural organization
23. Molecular simulations

Part 5 - Applications of self-assembling biomaterials
24. Cell-nanobiomaterials interactions
25. 3D cell culture
26. Regenerative medicine
27. Drug delivery
28. Diagnosis and biosensing
29. Surface modification of implants


No. of pages:
© Woodhead Publishing 2018
Woodhead Publishing
Hardcover ISBN:

About the Editor

Helena S. Azevedo

She has more than 15 years of research experience, in particular in biomaterials engineering, and has developed significant work on the development of self-assembling biomaterials (membranes, capsules) for biomedical applications (cell culture, regenerative medicine).

Affiliations and Expertise

Senior Lecturer in Biomedical Engineering and Biomaterials and Director of Operations of the Institute of Bioengineering, Queen Mary University of London, UK

Riccardo M. P. da Silva

His research work covers thermo-responsive polymeric nanoparticles for drug delivery, peptide self-assembly and supramolecular chemistry. Dr. da Silva has been invited by the European Research Executive Agency to evaluate research proposals and ongoing projects since 2011, and regularly reviews research papers in the Biomaterials Science field.

Affiliations and Expertise

12 years of research experience in the field of Biomaterials for Regenerative Medicine applications