Introduction (Sir Derek Barton). General aspects of selenoorganic chemistry. Selenoorganic functional groups. Selenocarbonyl and selenocarboxylic functional groups. Synthesis and properties of selenides. Selenoxides and selenones. Selenonium salts and selenonium ylides. Addition reactions. Addition reactions with cyclization. Selenium-stabilized carbanions. Unsaturated selenides, selenoxides and selenones. Hydroxy- and carbonyl-selenium structures. Oxidation reactions. Reduction reactions and other uses of selenium reagents. Special structures and natural products and biologically active compounds. Author index. Subject index.
The explosive growth of organoselenium chemistry over the past 12 years can be attributed to the specific properties of organic selenium molecules, which fit the requirements of modern organic synthesis. Most of them are well adapted to chemo-, regio- and stereo-selectivities. In addition, they can be used in mild experimental conditions which are compatible with the stability of both substrates and products in the preparation of unsaturated and functional complex molecules, especially in the field of natural products. This book describes and illustrates different synthetic routes to organic structures using selenium reagents or intermediates. The approach emphasizes that such transformations are simple, efficient and often carried out at room temperature. The scope ranges from the preparation of both inorganic and organic selenium reagents, through descriptions of structure, toxicity, biological aspects and nuclear magnetic resonance, to applications of specific selenium compounds in various syntheses including natural products and biologically active compounds.
Of interest to graduate and advanced undergraduate chemistry students as well as researchers in organic chemistry.
- © Pergamon 1986
- 29th September 1986
- eBook ISBN:
@qu:A convenient and thorough compilation of the literature through 1983 on the preparative chemistry of this important group of compounds...exceptionally clear, and the material, although very specialized, is accessible to undergraduate as well as graduate chemistry students. @source:Choice @qu:This book maintains the high standard set by earlier publications in the Pergamon Press Organic Chemistry Series. Professor Paulmier provides an extensive and well organized coverage of the relevant chemical literature up to December 1984... This excellent text represents good value for money and will be an important, if not essential, acquisition for any chemistry library. @source:Chemistry in Austrlaia
Université de Rouen, France