
Rosenberg's Molecular and Genetic Basis of Neurological and Psychiatric Disease
Volume 1
Resources
Description
Key Features
- Comprehensive coverage of the neurogenetic foundation of neurological and psychiatric disease
- Detailed introduction to both clinical and basic research implications of molecular and genetic understanding of the brain
- Detailed coverage of genomics, animal models and diagnostic methods with new coverage of evaluating patients with biochemical abnormalities or gene mutations
Readership
Clinical neurologists, psychiatrists, psychologists, neuroscience researchers, clinical neurology researchers, general medical practitioners, and genetic and molecular biologists with an interest in neurogenetics
Table of Contents
Introduction to the 5th Edition
Roger N. Rosenberg and Juan M. PascualSection I. GENERAL CONCEPTS AND TOOLS
1. Mendelian, nonmendelian, multigenic inheritance and epigenetics
Tamar Harel, Davut Pehlivan, C. Thomas Caskey and James Lupski
2. Genotype-phenotype correlations
Thomas D. Bird and Marie Davis
3. Immunogenetics of neurological disease
Ramyiadarsini I. Elangovan, Sreeram V. Ramagopalan and David A. Dyment
4. Pharmacogenomic Approaches to the Treatment of Sporadic Alzheimer's Disease using Cholinomimetic Agents
Judes Poirier, Justin Miron and Cynthia Picard
5. Application of Mouse Genetics to Human Disease: Generation and Analysis of Mouse Models
Teresa M. Gunn and Brenda Canine
6. DNA sequencing and other methods of exonic and genomic analysis
Jin Mitsui, Hiroyuki Ishiura and Shoji Tsuji
7. Association, cause and causal association: means, methods and measures
Walter Anthony Kukull
8. Gene Therapy for Neurological Disease
Theodore Friedmann
9. Direct induction of neural stem cells from somatic cells
Hideyuki Okano
10. Neuroimaging in Dementias
Prashanthi Vemuri, Melissa E. Murray and Clifford R. Jack
11. Cognitive Enhancers and Mental Impairment: Emerging Ethical Issues
Fabrice Jotterand, Jennifer McCurdy and Bernice Elger
12. Genetic counseling
Wendy R. UhlmannSection II. NEUROLOGIC DISEASES
13. Cerebral Malformations
William David Graf and Shihui Yu
14. Global Developmental Delay and Intellectual Disability
Michael Shevell and Myriam Srour
15. Down syndrome
Allison M. Caban-Holt, Elizabeth Head and Frederick Schmitt
16. An Overview of Rett Syndrome
Kristen L. Szabla and Lisa M. Monteggia
17. Fragile X-associated Disorders
Reymundo Lozano, Emma Hare and Randi J. Hagerman
18. Autism Spectrum Disorders: Clinical Considerations
Patricia Evans, Sailaja Golla and Mary Ann Morris
19. Metabolic and Genetic Causes of Autism
Sailaja Golla and Patricia Evans
20. Angelman syndrome
Charles A. Williams and Jennifer M. Mueller
21. Prion diseases
James A. MastrianniNEUROMETABOLIC DISORDERS
Mitochondrial Disorders
22. The Mitochondrial Genome
Eric A. Schon
23. Mitochondrial Disorders Due to Mutations in the Mitochondrial Genome
Salvatore DiMauro and Carmen Paradas
24. Mitochondrial Disorders Due to Mutations in the Nuclear Genome
Patrick Chinnery
25. Pyruvate dehydrogenase, pyruvate carboxylase, Krebs cycle and mitochondrial transport disorders
Mireia Tondo, Isaac Marin-Valencia, Qian Ma and Juan M. PascualLysosomal Disorders
26. Gaucher Disease – Neuronopathic Forms
Raphael Schiffmann
27. The Niemann-Pick Diseases
Edward H. Schuchman and Robert J. Desnick
28. GM2-Gangliosidoses
Gregory M. Pastores and Gustavo H.B. Maegawa
29. Metachromatic Leukodystrophy and Multiple Sulfatase Deficiency
Florian S. Eichler
30. Krabbe Disease: Globoid Cell Leukodystrophy
David A. Wenger and Paola Luzi
31. The Mucopolysaccharidoses
Reuben Matalon, Kimberlee Michals Matalon and Geetha L. Radhakrishnan
32. Mucolipidoses
Reuben Matalon, Kimberlee Michals Matalon and Geetha L. Radhakrishnan
33. Disorders of Glycoprotein Degradation: Sialidosis, Fucosidosis, Alpha-Mannosidosis, Beta-Mannosidosis and Aspartylglycosaminuria
William G. Johnson
34. Beta-Galactosidase Deficiency: GM1 Gangliosidosis, Morquio B Disease
William G. Johnson
35. Acid Ceramidase Deficiency: Farber Lipogranulomatosis and Spinal Muscular Atrophy Associated with Progressive Myoclonic Epilepsy
Michael Beck, Hugo W. Moser, and Konrad Sandhoff
36. Wolman Disease
Isaac Marin-Valencia and Juan M. Pascual
37. Lysosomal Membrane Disorders: LAMP-2 Deficiency
Kazuma Sugie and Ichizo Nishino
38. Fabry Disease: α-Galactosidase A Deficiency
Robert J. Desnick
39. Schindler Disease: Deficient-N-Acetylgalactosaminidase Activity
Detlev Schindler and Robert J. DesnickMetal Metabolism Disorders
40. Wilson Disease
Golder North Wilson
41. Menkes disease and other ATP7A disorders
Juan M. Pascual and John H. Menkes
42. Neurodegeneration with Brain Iron Accumulation
Susanne A. Schneider
43. Pantothenate-kinase associated neurodegeneration
Michael C. Kruer
44. Disorders of manganese transport
Isaac Marin-Valencia
45. Aceruloplasminemia
Satoshi Kono and Hiroaki MiyajimaVitamin Disorders
46. Genetic and Dietary Influences on Life Span
Yian Gu, Nicole Schupf and Richard Mayeux
47. Vitamins: Cobalamin and Folate
David Watkins, Charles Venditti and David S. Rosenblatt
48. Disorders of Biotin Metabolism: Treatable Neurologic Syndromes
Sara Elrefai and Barry Wolf
49. Disorders of Pyridoxine Metabolism
Clara van Karnebeek and Sidney M. Gospe Jr.Lipid metabolism disorders
50. Disorders of Lipid Metabolism
Stefano Di Donato and Franco Taroni
51. Lipoprotein Disorders
Mary J. Malloy and John P. Kane
52. Cerebrotendinous xanthomatosis
Vladimir Berginer, Gerald Salen and Shailendra B. Patel
Other Metabolic Disorders
53. Organic acid disorders
Margretta Reed Seashore
54. Glycogen Storage Diseases
Salvatore DiMauro and Hasan Orhan Akman
55. Disorders of Galactose Metabolism
Gerard T. Berry
56. Inborn Errors of Amino Acid Metabolism
William L. Nyhan and Richard Haas
57. The Urea cycle disorders
Nicholas Ah Mew, Maria Belen Pappa and Andrea Lynne Gropman
58. Glucose transporter type I deficiency and other glucose flux disorders
Juan M. Pascual, Dong Wang and Darryl De Vivo
59. Maple Syrup Urine Disease: Clinical and Therapeutic Considerations
David T. Chuang, R. Max Wynn, Rody P. Cox and Jacinta L. Chuang
60. Congenital Disorders of N-linked Glycosylation
Marc C. Patterson
61. Disorders of Glutathione Metabolism
Koji Aoyama and Toshio Nakaki
62. Canavan Disease
Reuben Matalon
63. Neurotransmitter disorders
Á. García-Cazorla and R. Artuch
64. Peroxisomal Disorder
Gerald V. Raymond
65. Disorders of Purine Metabolism
William L. Nyhan
66. The Porphyrias
D. Montgomery BissellDEGENERATIVE DISORDERS
67. Alzheimer's disease
Dennis J. Selkoe
68. Genetics of Parkinson Disease and Related Diseases
Jill Goldman and Stanley Fahn
69. Frontotemporal dementia
Shunichiro Shinagawa and Bruce Miller
70. THE Neuronal Ceroid-Lipofuscinoses (Batten Disease)
Sara E. Mole and Matti J. HaltiaMOVEMENT DISORDERS
71. The Inherited ataxias
Roger N. Rosenberg and Pravin Khemani
72. Friedreich ataxia
Massimo Pandolfo
73. Ataxia-telangiectasia
Shuki Mizutani
74. Dystonia
Katja Lohmann and Christine Klein
75. Huntington’s disease
Andrew McGarry, Frederick J. Marshall and Kevin Michael Biglan
76. Non-Parkinsonian Movement Disorder
Stanley Fahn and Jill Goldman
77. Hereditary Spastic Paraplegia
John K. FinkNEURO-ONCOLOGY
78. Glioblastoma
Elizabeth Maher and Robert BachooNEUROCUTANEOUS DISORDERS
79. Neurofibromatoses
David H. H. Gutmann and Adam Ostendorf
80. Tuberous Sclerosis Complex
Monica P. Islam and E. Steve Roach
81. Sturge-Weber Syndrome
Anne Comi, Douglas A. Marchek and Jonathan Pevsner
82. Hemangioblastomas of the Central Nervous System
Ana Metelo and Othon Iliopoulos
83. Incontinentia pigmenti
A. Yasmine Kirkorian and Bernard A. CohenEPILEPSY
84. The Genetic Epilepsies
Robert Macdonald and Martin J GallagherWHITE MATTER DISEASES
85. Multiple sclerosis
Stephen Lawrence Hauser, Jorge R. Oksenberg and Sergio E. Baranzini
86. Vanishing White Matter Disease
Orna Elroy-Stein and Raphael SchiffmannNEUROPATHIES AND NEURONOPATHIES:
87. The Genetics of Amyotrophic Lateral Sclerosis
Jemeen Sreedharan and Robert Brown
88. Peripheral Neuropathies
Steven S. Scherer, Kleopas A. Kleopa and Merrill D. Benson
89. Spinal Muscular Atrophy
Bakri Elsheikh, William David Arnold and John T. Kissel
90. Pain Genetics
William RenthalMUSCLE AND NEUROMUSCULAR JUNCTION DISORDERS
91. Dystrophinopathies
Eric P. Hoffman
92. Limb-Girdle Muscular Dystrophy
Wen-Chen Liang and Ichizo Nishino
93. The Congenital Myopathies
Heinz Jungbluth, Caroline Sewry and Francesco Muntoni
94. The Distal Myopathies
Ami Mankodi, Bjarne Udd and Robert C. Griggs
95. Hereditary Inclusion-Body Myopathies
Massimilliano Mirabella and Aldobrando Broccolini
96. The Myotonic Dystrophies
Richard Thomas Moxley III, James Hilbert and Giovanni Meola
97. Facioscapulohumeral Dystrophy
Rabi Tawil
98. Muscle Channelopathies: Periodic Paralyses and Nondystrophic Myotonias
Jeffrey Ralph and Louis Ptáček
99. Congenital Myasthenic Syndromes
Andrew G. EngelSTROKE
100. Cerebral Vasculopathies
Michael M. Dowling
101. Coagulopathies
Fenella Jane Kirkham
102. Sickle Cell Disease
Fenella Jane KirkhamSection III. PSYCHIATRIC DISEASE
103. Depression
Steven T. Szabo and Charles B. Nemeroff
104. Bipolar Disorder
Scott C. Fears and Victor I. Reus
105. Schizophrenia
David W. Volk and David A. Lewis
106. Obsessive-Compulsive Disorder
Michael Bloch, Jessica Lennington, Gabor Szuhay and Paul J. Lombroso
107. Tourette Syndrome
Jessica Lennington, Michael Bloch, Lawrence Scahill, Gabor Szuhay, Paul J. Lombroso and Flora Vaccarino
108. Addiction
Scott D. Philibin and John C. CrabbeSection IV. A NEUROLOGIC AND PSYCHIATRIC GENE MAP
109. A Neurologic Gene Map
Saima N. Kayani, Kathleen S. Wilson and Roger N. Rosenberg
Product details
- No. of pages: 1464
- Language: English
- Copyright: © Academic Press 2014
- Published: October 28, 2014
- Imprint: Academic Press
- eBook ISBN: 9780124105492
About the Editors
Roger N. Rosenberg

Affiliations and Expertise
Juan M. Pascual

Affiliations and Expertise
Ratings and Reviews
There are currently no reviews for "Rosenberg's Molecular and Genetic Basis of Neurological and Psychiatric Disease"