Rio-Hortega's Third Contribution to the Morphological Knowledge and Functional Interpretation of the Oligodendroglia

Rio-Hortega's Third Contribution to the Morphological Knowledge and Functional Interpretation of the Oligodendroglia

1st Edition - June 3, 2013

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  • Authors: Jose Iglesias-Rozas, Manuel Garrosa
  • eBook ISBN: 9780124116085
  • Hardcover ISBN: 9780124116177

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Pío del Rio-Hortega, one of the pioneering neuroscientists and discoverer of microglia, has been recognized as one of the most important Spanish neurohistogists of the past century. His landmark research on oligodendroglia, originally published in Spanish in 1928, has been translated into English for the first time by Dr. José R. Iglesias-Rozas and Prof. Manuel Garrosa. The book establishes definitively the concept of oligodendroglia and describes in great detail its structure, varieties, function, origin and pathology, providing a thorough review. The entire 1928 writing is presented, including the 79 excellent drawings and photographs from the original publication. To complement the original book and provide historical context, the translators have also included an introduction to the research and a biography of Pío del Rio-Hortega. This book constitutes a milestone in the history of neuroscience, biology and medicine, and it will be valuable reading for researchers and practitioners in these fields.

Key Features

  • First English translation of seminal 1928 research
  • Contains the broad descriptions and interpretations of the normal and pathological oligodendroglia
  • Full original text and new introductory sections


Researchers and practitioners working on Neuroscience, Glia, Neuroglia, and Oligodendroglia.

Table of Contents

  • Dedication



    Pío del Río-Hortega (1882–1945): A Biographical Sketch


    Preface references

    1. Introduction



    2. Bibliographic Background

    The “Mesoglia Cells” of Robertson

    Cajal’s Adendritic Corpuscles

    Initial Studies About Oligodendroglia

    Confirmation and Discussion

    Contradictory Ideas

    On the Functional Concept

    Relations Between Oligodendroglia and Nerve Fibers

    Abnormal Variations

    3. Material and Technique

    4. Morphological Characteristics of the Oligodendroglia




    Connections with Nerve Fibers and Vessels

    Expansional Plexus

    5. Textural Characteristics of Protoplasm in the Oligodendrocytes



    6. Morphological Varieties of Oligodendrocytes

    First Type

    Second Type

    Third Type

    Fourth Type

    Myelin Sheaths and Septa

    7. Abnormal Changes in the Oligodendroglia


    Progressive Phenomena

    Degenerative Phenomena

    Phagocytic Intervention


    8. Morphological and Genetic Kinship Between Astrocytes and Oligodendrocytes


    Transitional Forms

    9. Morphological and Physiological Parallelism of the Oligodendrocytes and Schwann Cells



Product details

  • No. of pages: 124
  • Language: English
  • Copyright: © Elsevier 2013
  • Published: June 3, 2013
  • Imprint: Elsevier
  • eBook ISBN: 9780124116085
  • Hardcover ISBN: 9780124116177

About the Authors

Jose Iglesias-Rozas

Affiliations and Expertise

Eberhard Karls Universität Tübingen, Germany

Manuel Garrosa

Affiliations and Expertise

Dept. Biología Celular, Histología y Farmacología. Facultad de Medicina, INCYL , Universidad de Valladolid, Spain.

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