Responsible Genomic Data Sharing

Responsible Genomic Data Sharing: Challenges and Approaches brings together international experts in genomics research, bioinformatics and digital security who analyze common challenges in genomic data sharing, privacy preserving technologies, and best practices for large-scale genomic data sharing. Practical case studies, including the Global Alliance for Genomics and Health, the Beacon Network, and the Matchmaker Exchange, are discussed in-depth, illuminating pathways forward for new genomic data sharing efforts across research and clinical practice, industry and academia.

• Addresses privacy preserving technologies and how they can be applied to enable responsible genomic data sharing
• Employs illustrative case studies and analyzes emerging genomic data sharing efforts, common challenges and lessons learned
• Features chapter contributions from international experts in responsible approaches to genomic data sharing

Active clinical and translational researchers across genetics, genomics, molecular biology, molecular diagnostics, and bioinformatics; pharmacologists; genetic counselors. Students at the graduate level and above in genetics, genomics, bioinformatics, molecular biology, and pharmaceutical science

Section I: Privacy Challenges in Genomic Data Sharing

1. Criticality of Data Sharing in Genomic Research & Public views of genomic data sharing

2. Genomic data access policy models

3. Information leaks in aggregate genomic data, inference attacks

4. genealogical search using whole genome genotype profiles

Section II: Privacy-Preserving Techniques for Responsible Genomic Data Sharing

5. Homomorphic encryption

6. Secure Multiparty Computing (MPC)

7. Game-Theoretic Approaches (for Genomic Privacy)

8. Hardware (SGX)